Lake house vacation rentals in South Carolina

Find and book unique lake houses on Airbnb

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Popular amenities for South Carolina lake house rentals

Waterfront lakehouse rentals

Guest favorite

Home in Anderson

4.75 out of 5 average rating, 51 reviews

Anderson-Lakefront* Near Greenpond*Pontoon Rental

JesseRating, 5 stars2 months ago
Very relaxing location, and cozy house
Guest favorite

Home in Saluda County

5 out of 5 average rating, 44 reviews

Lake Murray Paradise/Lakefront/Dock/Wifi/Sunrise

AprilRating, 5 stars4 weeks ago
We had a wonderful stay!! Very clean, comfortable, beautiful views, and very friendly and responsive host!! We will definitely be back!!
Guest favorite

Home in Lexington

4.97 out of 5 average rating, 150 reviews

Lakefront home on Lake Murray with private dock

DaniceRating, 5 stars2 months ago
This was one of the nicest Airbnbs we have ever stayed in! We immediately felt right at home and the house had every amenity you could think of needing. We loved how organized the kitchen was and it had everything we needed. The setting on the lake is beautiful, with the perfect indoor and outdoor spaces for our group to relax and spend time together. The house was so clean and comfortable. Chris was a wonderful host - friendly and responsive. We would absolutely recommend this house 1000% and hope we can stay here again sometime!
Guest favorite

Home in Ridgeway

5 out of 5 average rating, 16 reviews

Lake Front Log Cabin

Jo AnnRating, 5 stars1 month ago
Fantastic home in a beautiful location! Comfortable beds and all the needed amenities. Five stars!!
Guest favorite

Home in Iva

4.95 out of 5 average rating, 55 reviews

NEW Waterfront Lake Secession with Dock

ShannonRating, 5 stars2 months ago
House perfect for our Thanksgiving stay with family! Beautiful home, well appointed, clean, and private and serene location!
Guest favorite

Home in Anderson

4.95 out of 5 average rating, 110 reviews

Clemson ,Lake Hartwell, Waterfront, pontoon rental

MikeRating, 5 stars2 months ago
The house was exactly as billed. Tina was amazingly responsive. I contacted her about finding a tea pitcher. She showed up 10 minutes later with a tea pitcher AND some wonderful Asian tea. The house was clean and had plenty of room for a large number of guests. Two full kitchens. We were not able to take advantage of the outdoor attractions due to a cold snap in the weather. But, the outdoor features of the rental were great. And, the view was very nice. I liked it so much that I have recommended to my extended family that we use the place as a place for a staycation! Very impressed, and will rent again.
Guest favorite

Home in Townville

4.88 out of 5 average rating, 25 reviews

Relax on the lake in a home built to make memories

CaroleRating, 5 stars2 months ago
We loved this house. The beds were very comfortable and the house was immaculate. The setting is beautiful and so peaceful. Would definitely stay there again. Highly recommend!
Guest favorite

Home in Chapin

4.98 out of 5 average rating, 57 reviews

Lake front home, private dock, water toys, kayaks

AndreaRating, 5 stars3 months ago
Coastal chic with a twist of lake. The peaceful setting and modern conveniences of the “shack” were exactly what we were looking for (the heated bathroom floors and lights controlled by Alexa were some of our favorites). Our group of 8 had plenty of room to spread out and never felt cramped. Michell was very responsive and left great suggestions for exploring the area. I would not hesitate to book again!

Pet-friendly lake house rentals

Guest favorite

Home in Westminster

4.99 out of 5 average rating, 106 reviews

Dream Weaver: Lakefront• jacuzzi• dog friendly

CurtRating, 5 stars4 weeks ago
Our stay was peaceful & relaxing. Home & property was perfect! Thank you for hosting!!
Guest favorite

Home in Iva

4.98 out of 5 average rating, 176 reviews

Moonshine Bay

MargaretRating, 5 stars1 month ago
Moonshine Bay was the perfect place to spend the holidays. Very clean and comfortable with a beautiful view of the lake. We loved the outdoor space and hope to return when the weather warms up for the water sports! Thank you Jamie for a memorable vacation.
Guest favorite

Home in Anderson

4.99 out of 5 average rating, 193 reviews

Lake Escape

CoreyRating, 5 stars2 months ago
Such a beautiful place! Marissa was such a great host, very responsive and detailed. Cant wait to come back and stay again!
Guest favorite

Home in Townville

5 out of 5 average rating, 41 reviews

Best Times House-Lake Hartwell-Pontoon for Rent

EmilyRating, 5 stars3 months ago
Johanna was a lovely host and we had a great visit. There was plenty of space for our group of 10 and the driveway comfortably fit 3 cars. We loved the extra fridge for food/drinks storage and easy access to the water. Thanks so much!
Guest favorite

Home in Fair Play

4.93 out of 5 average rating, 27 reviews

Pet Friendly Lake House w/ Fenced in Yard

DavidRating, 5 stars1 month ago
Enjoyed our stay in a quiet and clean space. Appreciated host responsiveness- any issue was resolved immediately. Would love to stay here again!
Guest favorite

Home in Liberty Hill

4.93 out of 5 average rating, 59 reviews

Waterfront Lake Wateree / Simply Perfect (5 Star)

JeromyRating, 5 stars2 weeks ago
Amazing stay at this beautiful house. Everything was absolutely perfect.
Superhost

Home in Inman

4.92 out of 5 average rating, 78 reviews

Napoli family lake house. Our home is your home.

MelissaRating, 5 stars3 months ago
Had a great time and can not wait to come back . Interior was beautiful and very comfortable. Lake view is wonderful and we enjoyed it on their nice deck and screened in porch . Hosts were welcoming and gave great instructions for our arrival and getting settled . So sad we didn’t get to use the kayaks but maybe next time . Thanks for sharing your lake home with us !!!
Superhost

Home in Seneca

4.86 out of 5 average rating, 201 reviews

Cozy Lake House 5 miles from Clemson w Dock

ChristopherRating, 5 stars2 months ago
Awesome place only about 10 minutes from downtown Clemson. Well worth the visit.

Private lake house rentals

Superhost

Home in Anderson

4.8 out of 5 average rating, 10 reviews

Gorgeous Cabin by the Lake

GregoryRating, 5 stars3 months ago
Excellent place to stay. As advertised. Plenty of room for the 10 people we had. Quiet, private location. Great spot for a weekend Clemson football game!
Guest favorite

Home in Seneca

4.92 out of 5 average rating, 37 reviews

Beautiful Lakefront Home on Lake Keowee w/ dock

JarretRating, 5 stars2 months ago
Absolutely lovely home, highly recommend
Guest favorite

Home in Fair Play

4.84 out of 5 average rating, 19 reviews

Bobber Bungalow *level lot*fire pit*kayak*canoe

JessicaRating, 5 stars2 months ago
Beautiful house and scenery. Had a nice family vacation on the water. The house was perfect for a family. The boat bed was a hit with our daughter, she thought it was so cool. Nice patio with fire pit which is a plus. Neighborhood seems very safe. Very quaint town so it’s more of a relaxing and outdoorsy kind of vacation spot. Hosts are very responsive and friendly. Would definitely stay here again!
Guest favorite

Home in Cross Hill

5 out of 5 average rating, 16 reviews

Cabin Cove on Lake Greenwood

CindyRating, 5 stars4 weeks ago
Thoroughly enjoyed our stay at this spacious lake front home! The kitchen was so well appointed for our crew of 6. Spacious and livable with enough privacy for all! Awesome back porch overlooking the lake, and would definitely rent again! Thank you Marsela for your wonderful communication and accommodations!
Superhost

Home in Chappells

5 out of 5 average rating, 4 reviews

Private, Cozy Lakehouse

AlyssaRating, 5 stars2 months ago
Staying in this lakeside cabin was an unforgettable escape. Surrounded by breathtaking views and peaceful nature, it offered the perfect retreat. The cabin itself was charming and cozy, with large windows that framed the serene lake and its golden sunsets. Each morning, waking up to the sounds of birds and mist rising from the water was magical. Whether kayaking, hiking, or simply relaxing on the deck, it was a true sanctuary. This peaceful getaway was the ideal spot to reconnect with nature and unwind from the stresses of daily life.
Guest favorite

Home in Westminster

4.92 out of 5 average rating, 24 reviews

Peaceful 4 bedroom Lakehouse with no neighbors

MarquitaRating, 5 stars2 months ago
Perfect getaway for Thanksgiving with the family. The views, the lake, and the amenities were perfect and fit the descriptions listed. Andrew was an awesome host, very responsive and proactive. Highly recommend!
Guest favorite

Home in Starr

5 out of 5 average rating, 25 reviews

lakefront Home with million dollar view

JenniferRating, 5 stars3 months ago
Bruce was amazing!! The house on the lake was peaceful and relaxing.
Guest favorite

Home in Townville

4.95 out of 5 average rating, 41 reviews

Cozy cottage on deep water cove.

BrettRating, 5 stars2 months ago
We had a wonderful time in the Airbnb! The house was absolutely stunning and offered a great chance for us to catch the Clemson Vs. Citadel football game. Thank you for having us and have a wonderful holiday season!

Destinations to explore