Some info has been automatically translated. Show original language

Guesthouse vacation rentals in Charleston

Find and book unique guesthouse rentals on Airbnb

0 of 0 items showing
1 of 3 pages

Popular amenities for Charleston guesthouse rentals

Family-friendly guest house rentals

Guest favorite
An open living space is seen with a brown leather sectional sofa adorned with colorful throw pillows. A wooden coffee table sits in front of the sofa on a blue area rug. The kitchen features white cabinetry and modern appliances, with natural light filtering through a nearby window.
Guesthouse in James Island
4.91 out of 5 average rating, 704 reviews

Island Oasis—Near Downtown

JuliaRating, 5 stars1 week ago
Enjoyed our stay with our dog. Would love to stay again! The distance to folly beach and downtown charleston was ideal.
Top guest favorite
A cozy living area is visible, featuring a soft beige couch and a wooden coffee table. A clear vase holds dried flowers, adding a touch of nature. In the background, modern kitchen elements, including a coffee maker and green tile backsplash, can be seen.
Guesthouse in West Ashley
4.93 out of 5 average rating, 759 reviews

Charleston's Coolest Neighborhood

JohnRating, 5 stars4 days ago
Brett’s place was awesome!!close to everything and super clean!!Definitely would recommend and will stay again next time we are in the area!!!
Top guest favorite
Two classic cars are parked in front of a detached garage, showcasing a vintage white convertible and a sleek gray vehicle. The garage features two closed doors, framed by light green siding and surrounded by trees, adding to the serene environment.
Guesthouse in Summerville
4.88 out of 5 average rating, 795 reviews

New Loft in Historic Summerville

BrandenRating, 5 stars4 days ago
Jacquelynn is a very responsive and helpful host and everything about the loft was great. The check in and out instructions were clear and easy to follow. The Loft itself was clean and all the amenities were easy to find.
Guest favorite
A studio apartment is shown, featuring a king bed with decorative pillows and a comfortable couch. A wooden dining table and chairs are visible, alongside a chest of drawers. Natural light enters through two windows, creating a bright and inviting space.
Guesthouse in Mount Pleasant
4.94 out of 5 average rating, 250 reviews

Green Garden Studio @greengardenstudio2017

JosephRating, 5 stars1 month ago
Roomy clean and comfortable studio in a location that made it easy to get to all of the attractions surrounding Charleston. Would definitely stay again.
Top guest favorite
The living area features comfortable leather seating, a wooden coffee table, and a television on a wooden console. Natural light enters through large windows, and a subtle rug adds warmth to the hardwood floor. A separate entry door leads outside.
Guesthouse in Charleston
4.99 out of 5 average rating, 292 reviews

Spacious Daniel Island Apartment

JohnRating, 5 stars1 month ago
We had a great stay on Daniel Island. The neighborhood is quiet and attractive with miles of walking or biking paths. Beautiful pond 1 block away. The apartment is clean and bright, bed was super comfortable. Be prepared for a fairly long flight of stairs going up. The Charleston area has many great historical attractions plus many nice restaurants. We would recommend David and Shirlie’s place to anyone!
Guest favorite
A lush backyard features a wooden pergola draped with greenery, providing a shaded seating area. The well-maintained garden includes a variety of plants and flowers, enhancing the natural surroundings. The grass is neatly trimmed, offering a spacious area for relaxation.
Guesthouse in James Island
4.91 out of 5 average rating, 361 reviews

Mother in Law in James Island Riverland Terrace

SteveRating, 5 stars6 days ago
We enjoyed our stay. The location was excellent to go into downtown Charleston and the French Quarter. Very private.
Superhost
A charming yellow cottage is framed by lush greenery, with a cozy seating area featuring bright blue chairs. A colorful hammock hangs nearby, creating an inviting space for relaxation. Sliding glass doors lead into the cottage, promoting a cheerful and welcoming atmosphere.
Guesthouse in James Island
4.84 out of 5 average rating, 117 reviews

Romantic Beach Style Cottage close to everything!

DanielRating, 5 stars6 months ago
If you’re looking for a unique place to stay, that’s well situated between the beach and downtown, this is a great option. Anything this place lacks in square footage, it makes up for in character, charm and overall vibe. October mornings with the outdoor shower are not for the faint of heart, but I wouldn’t have it any other way. My wife loved the decor, outdoor lighting, plants in the shower, windows looking out to green-spaces. The bed is super comfy and cozy. Kokomo is awesome, we want to check out Roatan.
Top guest favorite
The entryway showcases an open door revealing a private deck with two outdoor chairs, framed by lush greenery. A modern kitchen area with dark cabinetry is visible, while a welcoming rug lies at the entrance.
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 133 reviews

5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!

AndrewRating, 5 stars5 days ago
Amazing treehouse in quiet and beautiful neighborhood, just wow! Short distance to shem creek that has plenty of restaurants, night life, and views. We took the bikes down a few times, only 5-10 minutes. Then you get to come home to peace and quiet. One of the most beautiful neighborhoods we have ever been in. Easy Uber into Charleston. If you want to be close to the action but not right in the middle of it, this is the place for you!

Guest house rentals with a patio

Guest favorite
Guesthouse in Harleston Village
4.94 out of 5 average rating, 36 reviews

Secret Garden Guesthouse

PatsyRating, 5 stars1 week ago
Lovely tucked away carriage house within walking distance of King Street, College of Charleston and very close to Colonial Lake. Wonderful stay very cozy and comfortable.
Guest favorite
An outdoor lounge area features a spacious sectional sofa in dark upholstery, surrounding a low wooden coffee table. Potted plants add greenery around the space. A shed with blue siding and double glass doors sits in the background, framed by tall trees and a wooden fence.
Guesthouse in West Ashley
4.94 out of 5 average rating, 236 reviews

Quaint Cottage Studio in Ashley Forest (Avondale), New Zealand

JenniferRating, 5 stars5 days ago
John and his family offer a cozy place to rest after exploring the nearby neighborhoods by foot and the region by car. A comfy bed, a responsive host, a central location and great local recommendations were highlights.
Top guest favorite
Guesthouse in Summerville
4.99 out of 5 average rating, 72 reviews

Hearts & Dreams Peaceful Family Retreat w/ pool

PaulaRating, 5 stars2 weeks ago
Welcoming, spacious, comfortable and everything you need. Enjoyed the natural, peaceful surroundings only a few minutes from historic Summerville. Perfect for our family of four with everyone having his/her own space. Easy drive to Charleston if timing is right. Holly is very responsive and helpful - much appreciated. :) Thank you for everything!!
Guest favorite
Guesthouse in West Ashley
5 out of 5 average rating, 5 reviews

Stylish Carriage House+Pool House

KylieRating, 5 stars1 week ago
Jessie & Robin were PHENOMENAL hosts. Our stay wasn’t long but it was peaceful, clean and just what we were looking for. The space was exactly as described. They were quick to respond and were proactive at check in and check out. Our time in Charleston was wonderful and the stay only added to that! If we find our way back to Charleston I will be booking with them again.
Guest favorite
A red efficiency building with a covered porch is surrounded by trees. Outdoor seating is arranged on the patio under the roof, complemented by potted plants. A barbecue grill is positioned nearby, providing a cozy area for sharing time outdoors.
Guesthouse in James Island
4.95 out of 5 average rating, 64 reviews

Country in the City, "The Outback"

SummerRating, 5 stars1 week ago
Fantastic host. Sue's Outback really is a little slice of heaven. The Outback was well equipped, as shown and very tidy. The pool was a HUGE bonus for our daughter. We can't forget Mr. Dobby, he's a wonderful pup with lots of personality. Thank you again for all your hospitality, Sue. Our family will be back soon.
Top guest favorite
A light-filled living area features a comfortable sectional sofa and a ceiling fan. Two windows provide natural light, while a TV is mounted on the wall. A decorative painting adds color above the sofa, and a woven area rug lies underfoot.
Guesthouse in Johns Island
4.96 out of 5 average rating, 113 reviews

Driftwood Cottage

RobertRating, 5 stars4 days ago
Terry’s place was even nicer than the photos. It was extremely clean with helpful instructions listed on the sideboard, even told us where to find the hair dryer (which I usually have to search for). The bed was very comfortable and the place was very quiet, so thankful to get a good nights sleep. Terry greeted us and asked if there was anything we needed. He was very friendly and thanked us for staying with him. We would love to stay there again.
Guest favorite
A shaded outdoor seating area is furnished with a comfortable couch and chairs, surrounded by tropical plants. A flat-screen TV is mounted on the wall, while a dining table awaits nearby. The entrance door adds a touch of charm to the inviting space.
Guesthouse in Park Circle
4.92 out of 5 average rating, 130 reviews

My Happy Place

HeidiRating, 5 stars1 week ago
Great place to stay at. had a amazing outdoor area and pool if only it was warm enough to have enjoyed it. there even was a TV outside but it was to chilly for us to sit out there. she had a heater if we needed it. super cute spot to stay and not far from downtown. Highly recommend
Top guest favorite
Guesthouse in James Island
4.99 out of 5 average rating, 152 reviews

The James: “Tiny” Home b/w Downtown & Folly

Mary JoAnnRating, 5 stars3 days ago
I almost hate to write this review. It was so wonderful that I’m afraid that once it gets out there, I won’t be able to book it again! Our experience completely matched the description of the place. Everything was top of the line from the make your own sparkling water to the wonderful mattresses on the beds. The decor was beautiful. Caitlin was very responsive & an excellent host. Most of all, I adored the location. It was peaceful with plenty of local restaurants. We thoroughly enjoyed James County Park. When you want to enjoy downtown Charleston, it’s just a quick Uber ride. All this & you can bring your dogs. Loved it & can’t wait to stay again.

Guest house rentals with a washer and dryer

Top guest favorite
A detached two-car garage is visible, featuring brown doors and white siding. Above the garage, a cozy guest house is present, capped with a pitched roof and adorned with multiple windows. Lush greenery surrounds the structure, enhancing the outdoor space.
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 146 reviews

Groves Carriage House, near Shem Creek

JimiRating, 5 stars4 days ago
Wonderful, responsive hosts. This above garage unit has everything you need. The neighborhood is very accessible to anywhere you want to go. 5 minutes from Shem Creek. 15 minutes to Sullivan’s Island or Isles of Palms. Roughly 10-15 minutes from Downtown Charleston. The hosts were very helpful with any of my simple needs. I would definitely stay here again.
Top guest favorite
A serene waterfront view is presented, featuring calm waters reflecting the soft colors of sunset. Lush green grass and trees frame the scene, while a wooden pier extends into the distance. A gathering area with shelter is visible, adding to the inviting landscape.
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 148 reviews

Beach, downtown, Alhambra Hall weddings so close!

ChrisRating, 5 stars3 weeks ago
Very accommodating. Felt like home. Beautiful, peaceful neighborhood in a convenient location. Great communication with host and easy check in/out. Would definitely choose to stay here if in the area again. Recommend!
Top guest favorite
The exterior of the garage apartment is presented with a light grey facade. A gabled roof enhances the structure's height. The garage door features three sections with paned windows at the top, while surrounding greenery and a simple front pathway contribute to a welcoming atmosphere.
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 245 reviews

Cozy Apartment in Mount Pleasant

LisaRating, 5 stars1 month ago
Dottie’s place was as described and had everything we needed. It was comfortable and in a quiet neighborhood. We will definitely come back when visiting the area.
Guest favorite
A colorful row of historic buildings features facades painted in pastel hues, including green, blue, and pink. Windows adorned with shutters and wrought iron accents contribute to the charm of this Charleston street. A few vehicles are parked along the curb, and trees provide a natural border.
Guesthouse in West Ashley
4.9 out of 5 average rating, 616 reviews

Cozy Cottage Escape Near Avondale w Bike Path!

JessilynRating, 5 stars1 week ago
Loved staying here! I have booked this place multiple times because we enjoyed it so much. Great hosts!
Guest favorite
The cottage's exterior features a welcoming front porch with two chairs flanking the entrance. Wooden double doors are framed by two lanterns, while neat landscaping includes a grassy area and stone pathway leading to the entry.
Guesthouse in Mount Pleasant
4.94 out of 5 average rating, 107 reviews

Private Coastal Cottage-Near Beaches & Charleston!

ZacharyRating, 5 stars8 months ago
Thank you again for hosting us. The place was in a perfect location, and you all were very accommodating. Great storage if bringing a boat down, and Jaime and her husband are very welcoming. Would recommend this place to all
Top guest favorite
A well-lit entrance features a white door with a lantern light above. Two stylish chairs and a small round table sit on a wooden deck, which is bordered by lush greenery that offers privacy and a serene atmosphere.
Guesthouse in James Island
5 out of 5 average rating, 250 reviews

James Island "La Casita" Nestled btw Beach & City

MichaelRating, 5 stars4 weeks ago
John and Leah's apartment was a wonderful place for us to stay during our visit to Charleston. It was very clean and bright with very attractive furnishings. It was about a 20 minute drive to the center of the city but was a nice, quiet respite when we weren't touring. John and Leah very very responsive to our questions and very accomodating to our needs. We would love to stay there again.
Top guest favorite
A charming street scene features a collection of historic buildings with warm-colored facades and elegant shutters. Tall trees provide shade, while window boxes with greenery add a touch of vibrancy. A passerby strolls along the sidewalk, embodying the inviting atmosphere of the neighborhood.
Guesthouse in Summerville
4.97 out of 5 average rating, 258 reviews

Summerville’s Tiny Oak Hideaway

BrittanyRating, 5 stars5 days ago
Loved staying in this cute little cottage! Perfect amount of space for myself, a friend, and her newborn! Very peaceful and in walking distance to local coffee shops + more! Justin sent recommendations and the check in was easy. Will be back :)
Top guest favorite
A charming outdoor patio area features two white folding chairs and a small round table, surrounded by vibrant greenery. The entrance is framed by wooden fencing and a decorative fish has been mounted on the wall above the door, adding a unique touch to the space.
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 287 reviews

#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!

KathleenRating, 5 stars1 week ago
Paige and Perry were excellent hosts. The apartment is exactly as described and more. Spotlessly cleaned with nice extras like coffee/tea and creamer. Perfect for us and our baby. Paige even set up the pack n play for us as we were arriving late at night. Having baby essentials like that and the high chair was hugely helpful. The location is perfect, easy drive downtown and close to beaches. We can’t want to stay here again!

Quick stats about guesthouse rentals in Charleston

  • Total rentals

    220 properties

  • Total number of reviews

    25K reviews

  • Family-friendly rentals

    40 properties are a good fit for families

  • Pet-friendly rentals

    60 properties allow pets

  • Rentals with a pool

    10 properties have a pool

  • Rentals with dedicated workspaces

    100 properties have a dedicated workspace

Destinations to explore