House vacation rentals in Lake City

Find and book unique houses on Airbnb

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Popular amenities for Lake City house rentals

House rentals with a pool

Guest favorite
Home in Gainesville
5 out of 5 average rating, 8 reviews

3bed 2 bath with POOL!

LauraRating, 5 stars3 weeks ago
Such a lovely home! We loved using the pool. The kitchen is well-stocked with gear! The beds were super-comfy. Slept like a dream!
Guest favorite
Home in Gainesville
5 out of 5 average rating, 13 reviews

Private Home with Covered Pool

KimberlyRating, 5 stars4 days ago
Beautiful spacious home in quiet neighborhood. Home was very clean! Has everything you need! 10/10 would recommend.
Superhost
Home in Steinhatchee
4.83 out of 5 average rating, 12 reviews

Pura Vida House with pool

JaciaRating, 5 stars4 months ago
It was a beautiful home and quiet neighborhood. Lots of room inside and out.
Top guest favorite
Home in Southwest Jacksonville
4.96 out of 5 average rating, 162 reviews

+A Taste of Britain entire house / heated pool+

Ashley Rating, 5 stars2 days ago
Stay was amazing, had no issues and James was easy to reach and excellent with responses, house was clean, nice in a great area and very well equipped with everything we needed! Will use again!
Superhost
Home in Gainesville
4.65 out of 5 average rating, 83 reviews

Gator Pool and Hot Tub House -1.5 miles to Stadium

KathRating, 5 stars2 months ago
Stayed for an only a few days as I was visiting family around area and it was so peaceful and quiet and amazing for only a few days . It was well taken care of and spotless when I walked in and anytime i had a question I always received a response requested pool heat to be turned on and Hot tub sometimes too and then was quickly answered and action was taken. Ten out of ten I would LOVE to stay here again ! Not even just because it’s nearby family but because it was so peaceful and relaxing to just stay in general . I would definitely recommend !!
Top guest favorite
Home in Live Oak
4.92 out of 5 average rating, 12 reviews

Spacious Privacy Party Pool Home

LauraRating, 5 stars1 month ago
Cozy family house with plenty of room for the family.
Superhost
Home in Alachua
4.82 out of 5 average rating, 222 reviews

Gated Golf Getaway close to Springs and UF

AmandaRating, 5 stars2 weeks ago
We were in Gainsville for a competition, and it was home.
Guest favorite
Home in Gainesville
4.86 out of 5 average rating, 65 reviews

Vacation home, Pool,gazebo, yard

BryantRating, 5 stars1 month ago
Ravit was a great host, I told her I may need to check in early because I arrive earlier than expected. She was able to accommodate me. I ended up running errands and checked in late anyway. It was nice to know that I could. House was immaculate. King size bed was extremely comfortable. I was here for business and I slept like a baby. I definitely recommend that you see it for yourself. The price was nice as well.

Weekly house rentals

Top guest favorite
Home in Fort White
5 out of 5 average rating, 18 reviews

FL Springs Retreat for Diving, Art, & Photography

LashbrookeRating, 5 stars1 month ago
We had a great stay and really enjoyed our selves. Great communication and always helpful.
Guest favorite
Home in Gainesville
4.8 out of 5 average rating, 189 reviews

Very Spacious house 6 miles from U of FL VA/Shands

AngelaRating, 5 stars3 weeks ago
Linda’s place was exactly what I needed for my vacation. It was close to my event that was going on, very comfortable, and had everything we needed for our stay. Linda responded very quickly to any questions I had. I would definitely recommend staying here to anyone looking for a place in this area. I will book again next time I am in the area!
Top guest favorite
Home in Alachua
5 out of 5 average rating, 23 reviews

Retro Revival - Mid-Century Refuge w/a '70s Twist!

ArnoldRating, 5 stars4 days ago
This is a very beautiful home. Very spacious and clean. Lots of bedrooms with a bunk bed. There’s TV in every bedroom.
Top guest favorite
Home in Gainesville
4.99 out of 5 average rating, 121 reviews

The Mangrove Suite. Newly Built, Upscale, Central

JulieRating, 5 stars1 month ago
The Mangrove Suite was so beautiful, clean, and comfortable. We especially enjoyed the adorable balcony, great showers, and super comfortable beds. We also appreciated the labeled drawers and lights, recommendations, ease of check in/out, and a very helpful delayed check out. We will definitely stay again when in the Gainesville area!
Guest favorite
Home in Gainesville
4.79 out of 5 average rating, 135 reviews

Beautiful Family home located downtown & VA, UF🏈

ChadRating, 5 stars1 month ago
Myself and three friends were there for one night. Yenni was clear on check-in instructions and the place was exactly as listed. It was very close to any and everything in Gainesville! Thank you for your hospitality!
Guest favorite
Home in O'Brien
4.86 out of 5 average rating, 119 reviews

The Hidden Palms

TimothyRating, 5 stars3 weeks ago
Randy was an awesome host, and an exemplary example of true hospitality. After checkout, we unexpectedly needed to stay another night in the area. we assumed we wouldn’t be able to rebook with Randy after just checking out the same day but, after reaching out, he quickly replied and let us come right back for the night.  He was extremely communicative throughout our entire stay. We accidentally left a few belongings behind which Randy promptly offered to ship out to us. Randy’s daughter was very kind and, had she not offered us a hand when looking for the light switch to the grill area, we never would’ve known she was there. The home is beautifully situated on a private and peaceful lot in the country, but close to local Springs and restaurants. We felt right at home and thoroughly enjoyed our stay. I highly recommend Randy’s home to anyone looking to stay in the area, and definitely plan to stay again in the future. Thank you!
Top guest favorite
Home in Gainesville
5 out of 5 average rating, 13 reviews

A Dream Getaway Family-Friendly near UF Stadium!

ReggieRating, 5 stars4 days ago
Great location close to UF. Private fenced lot. Would definitely stay again
Superhost
Home in Branford
4.88 out of 5 average rating, 104 reviews

Ichenucknee/Ginnie Springs & Divers woods retreat

UrsulaRating, 5 stars1 month ago
The host behaved excellently in addition to her kindness she was extremely collaborative in a mishap that happened. The house and place are cozy and close to all the Springs we wanted to visit.

Private house rentals

Top guest favorite
Home in Live Oak
4.97 out of 5 average rating, 106 reviews

Your home when ur gone from urs

TanyaRating, 5 stars1 week ago
Anita's Airbnb was lovely. Everything was spotless and in order. I was cycling daily nearby at Florida Bike Safari, and the idea to stay here in the evening was perfect. If you need a place for a few days in Live Oak, this is an excellent choice. Thanks, Anita!
Guest favorite
Home in Jennings
4.94 out of 5 average rating, 148 reviews

Gated 5 Acres "Walkers Run"

AdamRating, 5 starstoday
Airbnb can be a train wreck so our family feels blessed to have found Cynthia’s place. We couldn't possibly say enough nice things about this 5-star home! The house is new construction and literally belongs in a Martha Stewart Magazine. Comfy beds, plush sofa, amazing kitchen, endless hot water (I’m 6’4” and could even fit under the shower head), cold A/C, huge fridge, coffee, Netflix, fireplace and fire pit, screened in patio, parking for our trailer, exercise equipment, BBQ, gated security, board games and fast Wi-Fi for the kids. On top of it all, Cynthia was super responsive with any questions. She is the exact reason we prefer Airbnb over hotels. Thank you for creating a home away from home for those of us on the road!
Top guest favorite
Home in Live Oak
4.79 out of 5 average rating, 107 reviews

Pharmhouse

ChristiRating, 5 stars1 week ago
We loved this place. It was very clean, private, and peaceful, which was just what we were looking for to celebrate my daughter's birthday. We loved the peacocks too. We would definitely book here again.
Superhost
Home in Lake City
5 out of 5 average rating, 10 reviews

Charming & Quaint Home in a quiet Cul De Sac

JamesRating, 5 stars25 months ago
The housewas spotless and had everything we needed. Very quiet neighborhood. And Kimberly was very responsive. Will definitely try staying here againwhen we are working in the area.
Guest favorite
Home in Perry
4.87 out of 5 average rating, 23 reviews

Cozy & peaceful house in Perry Florida

KatriceRating, 5 stars1 month ago
Great home and hosts! Looked just like the pictures! We would stay here again!
Top guest favorite
Home in O'Brien
4.97 out of 5 average rating, 122 reviews

Good country living scuba diving capital

JustinRating, 5 stars4 months ago
Michael’s place was perfect for what we needed. It’s in the country with a decent amount of space outside for bonfires or hanging out. Had 3 beds and a couch, kitchen with the necessities, laundry and a couple of bathrooms that had towels and body wash. Michael lives in a house just behind the airbnb so you’ll see him as he works in the yard and his dogs will come greet you. There is plenty of parking space even for a truck and trailer plus a couple cars. The house was simple but tidy. And for cave divers it’s in a central location to some of Florida's best known cave systems.
Top guest favorite
Home in Southwest Jacksonville
4.97 out of 5 average rating, 254 reviews

Single House: 12guests/4beds/2baths/huge backyard

LaurieRating, 5 stars2 weeks ago
Wonderful stay! We only needed to stay for one night but would have been extremely comfortable if we had needed to stay longer. We had five in our party. The house is very spacious and is exactly as described. Host was helpful with questions and helpful with other accommodations that were needed. Quiet area and absolutely perfect for a family. I highly recommend this house. We will be returning. Thank you for a perfect place.
Top guest favorite
Home in Citra
5 out of 5 average rating, 9 reviews

Charming farm ~5 bedroms + pool + stables near WEC

KevinRating, 5 stars1 month ago
The property is peaceful, and Sam is very accommodating.

Quick stats about house rentals in Lake City

  • Total rentals

    30 properties

  • Nightly prices starting at

    $40 before taxes and fees

  • Total number of reviews

    810 reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Pet-friendly rentals

    10 properties allow pets

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

Destinations to explore

  1. Airbnb
  2. United States
  3. Florida
  4. Columbia County
  5. Lake City
  6. House rentals