
Lake house vacation rentals in Santee
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Top-rated lake house rentals in Santee
Guests agree: these lake houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santee lake house rentals
Waterfront lakehouse rentals

Dream nest water-front stay
Great place to stay for the Masters.

Lovin’ Lake Life
This was such a nice little stay! It was a bit chilly most mornings of our trip, but the enclosed porch was great for coffee and morning conversation. Beds were super comfy too!

Off The Mainland with Optional Pontoon Rental
Took my wife,daughter, dogs and in laws to visit family over Thanksgiving break, what a great stay! Loved the location on the water, amazing view, comfortable home, great game room upstairs and easy parking. I can't say enough good things about our stay. Kitchen was fully stocked with enough to cook a whole Thanksgiving dinner. We made some great family memories here, thank you! I could write a short book about all the great things this property has but I'll finish here, well worth the money and the hosts were great too. Stay here for a great time!

The Lakeside Haven
Me and my family had stayed here before right after the hurricane in October of 2024. Not much has changed since then, which is amazing! Dan and Linda are the sweetest hosts and an amazing couple! We definitely can't wait to stay again and enjoy the water once more.

Peaceful lake house near Columbia - sleeps 7
We had an amazing stay! The property offers breathtaking views and is perfectly situated near a beautiful lake—ideal for a peaceful getaway. The home was clean, cozy, and had everything I needed. The owner was incredibly responsive and easy to communicate with, making the entire experience seamless. We highly recommend this place for anyone looking for a serene and relaxing retreat. Would definitely stay here again!

Cozy 3 bed 2 bath on the waterfront
From first reaching out to Kathy about parking for our group, to her reaching back out to check on us day before coming in...Kathy was a very responsive host. Her property was as advertised and was a perfect location for our group of fisherman. Everything we needed for a relaxing 3 day weekend was provided including a bowl of snacks!! We didn't use the boat ramp on property, but that along with the dock was a plus for boaters. Ample parking for 4 bass boats on trailer. With the impending bad weather she was very accommodating for us to possibly check out late if needed. Only thing I will point out is master bath has a senior style walk in tub. A little tight for a big fella like myself. If available on our next trip, won't hesitate to rent this property again. Thank you again Kathy!!

Sunrise and Sunset on the Lake
Beautiful home. Surrounding outdoors were stunning. Home was comfortable and warm. Plenty of room for a group of 6 (+ baby).

Casa Azul - Lake Murray - Close in - Spa like bath
We enjoyed our week at the lake and found the home well-stocked. We ate most of our meals at home and had everything we needed. The kitchen was nicely appointed, and the appliances were high quality. There is a Publix grocery store 10 minutes away and several local restaurants to enjoy. We used the charcoal grill for several meals and sat outside as much as possible. The whole family enjoyed the kayaks, paddle boards, canoes, and swimming in the lake. A ladder on the dock would make it easier to get out of the lake, but we made due.
Pet-friendly lake house rentals

Private ramp and dock, 5 mins from Liberty marina
Really enjoyed our stay. Host very communicative during our stay. Beautiful home with lots of space.

Lakehouse
Great cabin by the lake and close to lake access! Clean cabin with all you need for a fishing trip. Great restaurant within 75 yards of the cabin open from breakfast at 7 till 9-10 at night. Great fishing in the area!! Boat parking is a little tight with a 20 ft rig on the back but we made it work by backing in. All in all a great place to stay!!

The Heron Lake House
The perfect stay! Beautiful lake, clean and gorgeous house, quiet neighborhood and amazing bang for your buck. We've stayed at a dozen Air B&B's and this was top 3! Plenty of space for our family of 5 (though could have EASILY fit another 3-5 guests). Never felt like we were falling over one another. Great fishing location (though we only caught one fish, haha), calm waters and breathtaking sunrise/sets. About an hour drive from the beach at Charleston (highly suggest Folly Beach). Morgan was responsive when we had questions and was always super kind.

3 BR - 10 Minutes to Downtown w/ Lakefront Deck
Clean easy budget friendly stay. Nice to relax on the deck with the water.

A Lake Slice of Heaven
Place was very nice. Convenient for our bass tournament. Carlos was an excellent host.

Hideaway on Lake front for 7 guests
Very clean and spacious house with more than reasonable stocked items made us feel at home the minute we stepped in. Inside, tasteful furnitures and decoration gave us a cozy feel as if we are staying at my grandmother’s house. Outside, you can spend all day relaxed with the sounds of nature - water, wind, and birds. I tried kayaking for the first time. Water is calm, nothing else is around me except water. What a soothing experience! And the sunset is breathtaking.

Cozy 3 bed 2 bath waterfront lake house
The host was great and the place was as described. We had enough space for everyone to sleep. I wish we had more time to enjoy the water but our schedule did not allow.

Nordic Haus: Modern and Peaceful Central Location
David’s place was great- spacious, bright, and comfy. We would definitely stay there again!
Private lake house rentals

The Fishnet
Perfect place to stay for quick access to the lake and very clean. Great neighborhood.

Shady Cove on Fountain Lake
Plush and perfect. Loved every inch of this comfortable home. If you love to cook great prep space. Host responsive and always helpful. Will always try to stay here when in town.

Paradise on Lake Marion
I travel a lot for fishing tournaments and typically stay at AirBNB or VRBO places instead of hotels. This place was as pictured. This is the first one that I’ve stayed at that was actually someone’s “home”. It appears as if the owners just move into a small outbuilding in the back yard while their home is rented out. This didn’t bother me, but it may bother some. It seemed to be a safe place to plug the boat up and is close to boat ramps.

Located on big water with private dock
We stayed for the weekend of our daughter’s wedding at Heron Hill Venue. The location was great and the scenery beautiful. The lake house is well equipped, comfortable, and decorated but not cluttered. The deck overlooking the lake was the perfect place to sit in the morning and relax with my hot cup of tea before wedding preparations got crazy. Only wish we’d had more time to enjoy it. Kim was very helpful and responsive. I would come back again even without a wedding to attend. High marks for this lake house retreat!

SANTEE LAKE MARION GOAT ISLAND AREA NEWLY UPDATED
Responsive host by text and phone. Super helpful with the questions I had about parking. The house was clean and everything we used worked as it should. We will be back next year for sure.

Charming two bed one bath
We had a wonderful stay at this Airbnb. It looked like the photos. Lori was very responsive and helpful. Prime location near shops and resturants. GORGEOUS water view. We will be back!

Heated Indoor Pool on Lake Marion with Dock
It was a great place for our whole family. It checked all the boxes for everyone. Fishing was our #1 box, having the boat dock was wonderful. They didn't have to take the boat in and out of the water everytime they fished. The indoor swimming pool was great for the kids and adults because you didn't have to wait for warm weather. The pool table was fun for all and we could all hang together in the spacious area. The kitchen was large and clean with everything you would need. We all had a great relaxing vacation. Would highly recommend this place! Working with Ingrid was wonderful! She was extremely helpful and was available when we needed her. Would love to check out her other properties. Thank you for everything Ingrid!

Enjoy Lake front access @Baylife_LakeMurray
Garrett was very responsive and friendly. We rented this place to bass fish Lake Murray. The driveway was big enough to hold our trucks and trailers. We were able to tie our boats at the docks or beach behind the house. Very nice! The house was exactly as described in the pictures and we have no complaints. I also want to say the residents of Lake Murray were the friendliest folks we have ever met! People on docks just come out to talk and welcome us to their Lake. I highly recommend Garrett and this house for your next stay in Lake Murray.
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