Santee vacation rentals

Book unique vacation rentals, houses, and more on Airbnb

0 of 0 items showing
1 of 3 pages
0 of 0 items showing
1 of 12 pages

Popular amenities for Santee vacation rentals

Stay near Santee's top sights

Clark's Restaurant11 locals recommend
Captains Quarters Seafood and Steak11 locals recommend
Lonestar BBQ & Mercantile10 locals recommend
Armando’s Mexican Restaurant10 locals recommend
Lake Marion Golf Course7 locals recommend
Food Lion7 locals recommend

Santee house rentals

Top guest favorite
A cozy living area features a light-colored sectional sofa adorned with colorful throw pillows, accompanied by two wooden chairs. A vibrant red patterned rug covers the floor, while a wooden sideboard and a large flat-screen TV are positioned along the wall.
Home in Sumter
5 out of 5 average rating, 68 reviews

The Oasis

ErinRating, 5 stars6 days ago
We stayed while visiting family in the area with our two boys. The space overall was perfect for our family of 4. It was close to all the places we were visiting and the hosts also provided great recommendations for restaurants. The neighborhood was very quiet as well! Only downside would be that the front room did not have black out curtains, otherwise a wonderful stay.
Top guest favorite
A spacious patio area features a round dining table surrounded by metal chairs. Nearby, a swing chair and a lawn are visible, framed by trees with hanging Spanish moss. A shed is situated in the background, complementing the tranquil outdoor setting.
Home in Goose Creek
4.98 out of 5 average rating, 96 reviews

Charming Ranch House

JamesRating, 5 stars2 weeks ago
Finding a affordable place to stay to visit Charleston at a affordable price is extremely difficult. That is what I discovered. You can either get scalped downtown paying thousands - maybe a night - for a mediocre hotel, or take a chance to get a vrbo or airbnb close to town and get junk house in a slum neighborhood. I had to go to a wedding. So did other family members. I tailored my search for highest guest ratings and this property came up. Yeah it took 30 minutes to drive to town. but again - anything closer was a slum or a 1000+ a night in town. I was pleasantly surprised. This property is a older ranch in a middle class neighborhood that has been COMPLETELY remodeled - and I mean COMPLETELY. New appliances, new flooring, new paint, the furniture may be original but it was comfortable. The neighborhood was quiet and safe, and it was easy to travel to the city and easy to get back. My other family members picked a airbnb rental in Mt Pleasant - spent $3000 on a dump.
Guest favorite
Home in North Charleston
4.91 out of 5 average rating, 105 reviews

NEAR HISTORIC DOWNTOWN | LAKE ACCESS + BALCONY

PhoenixRating, 5 stars2 weeks ago
We had a great stay at Daniel place. Everything was in order and it allowed to have an awesome weekend for the Cooper River Bridge Run.
Superhost
A cozy living room is presented with red walls and hardwood flooring. Two comfortable sofas and a coffee table with a decorative surface are arranged, complemented by a floor lamp and an entertainment center. Natural light flows through multiple windows, enhancing the welcoming ambiance.
Home in Cayce
4.77 out of 5 average rating, 151 reviews

3/1.5 house in Cayce Close to USC, Ft Jackson, CAE

JoseRating, 5 stars1 week ago
Joseph place was really comfortable and cozy. Joseph is a great host very responsive and accommodating. House has everything you need. Thanks Joseph!
Top guest favorite
A spacious living area features a high ceiling, two lamps providing warm lighting, and a comfortable seating arrangement that includes a large sofa and armchairs. A coffee table occupies the center, adorned with decorative items. Natural light enters through a nearby window.
Home in Sumter
4.95 out of 5 average rating, 43 reviews

LODGING @ OLD TOWNE LANDING SUITE A

DemitriusRating, 5 stars1 week ago
Very nice house, quiet neighborhood. Also military friendly, would definitely stay again!!
Superhost
A living room features natural light flowing through large windows, illuminating a cozy seating arrangement with a white sofa adorned with colorful cushions. A glass coffee table sits atop hardwood flooring, accompanied by a decorative plant. A comfortable chair and gray couch add to the inviting atmosphere.
Home in Park Circle
4.88 out of 5 average rating, 256 reviews

Island House Blue

MadelynnRating, 5 stars1 week ago
Was a great place to stay! Very cute and cozy. Although it was off a busier road you couldn’t really tell from inside and it felt pretty quiet. Would recommend!
Guest favorite
A single-story brick home is featured, showcasing large blue shutters on the front windows. A green lawn leads to a covered porch with steps. An attached garage is visible on the right, with vehicles parked inside.
Home in Dalzell
4.86 out of 5 average rating, 21 reviews

Beautiful Home Away from Home Near Shaw AFB

FranciscoRating, 5 stars7 months ago
Great location, we had no problems at all with this beautiful home and host!
Guest favorite
The exterior of a single-story brick house is depicted, featuring a covered carport and a concrete driveway. Large windows provide natural light to the interior. The surrounding grass and landscaping are well-maintained, contributing to a neat appearance in a quiet residential area.
Home in North Charleston
4.95 out of 5 average rating, 216 reviews

FANTASTIC PRICE!! FOR CHARLESTON 2 BEDROOM HOUSE

D.MRating, 5 stars1 month ago
Tony's place was exactly what we needed. Very close to the Art Center, Coliseum and an Shopping Outlet. The host was very friendly, responsive and understanding. We appreciate the details he puts to have his guests feels at home. We love the background music when you first get to the house..... was a nice welcoming after a long drive.

Other great vacation rentals in Santee

Guest favorite
The kitchen features gray cabinetry complemented by light-colored countertops. A sink is positioned between the countertop and a white oven. A refrigerator and a microwave are also visible. The floor is laid with tiled patterns, and a small mat is placed in front of the sink.
Home in Sumter
4.93 out of 5 average rating, 100 reviews

Welcome! a relaxing retreat...home away from home

BrendaRating, 5 stars1 month ago
I have no complaints. The home was very nice and clean. We're we're very satisfied.
Top guest favorite
A scenic view from the balcony shows a tranquil lake and adjacent pool area. Palm trees and lush landscaping frame the space, creating a relaxing outdoor environment. The calm water reflects the sky, enhancing the serene lakeside atmosphere of the property.
Condo in Santee
4.96 out of 5 average rating, 144 reviews

Beautiful lakefront condo overlooking Lake Marion.

GloriaRating, 5 stars1 week ago
If you're looking for a place to be relaxed and revitalized ,this is your destination! It's 💯 for me!!
Top guest favorite
The image showcases a scenic view of a calm lake from a deck area. Several outdoor chairs are positioned along a railing, with lush green grass and trees framing the water. A private dock is visible, extending into the lake.
Home in Summerton
4.99 out of 5 average rating, 106 reviews

Cheerful 3 bedroom home on the lake

HollyRating, 5 stars2 weeks ago
Absolutely beautiful! The place was clean and inviting. The hosts had provided everything you could possibly imagine, even personal items if you forgot anything. There was so much to do for entertainment both inside and outside the home. We had a great time!
Top guest favorite
An electric fireplace is framed by a black surround, featuring glowing blue and orange flames. A decorative log piece lies within the firebox, and a sign reading 'HOME SWEET HOME' rests below, adding a touch of warmth to the living area.
Condo in North Charleston
4.96 out of 5 average rating, 50 reviews

2 Beautiful Master Suites

EthelRating, 5 stars1 day ago
Kathy’s place was very nice and comfortable. Close to Brecks where we got a 30 oz steak for $32.99 was not a fancy place, but it was worth it and the steak was awesome. Another place we ate on the way out was in Somerville. Shuckin shack oyster bar. They had a great menu low price for the best oysters, clams and mussels. Steamed or raw also a great fried cod sandwich. I am sure everything there was awesome!! Oh good Bloody Mary too! The proximity of Karen’s place to a lot of things to do was nice. She also left us much appreciated wine and a gift. Thank you Kathy for a great stay!
Guest favorite
A view of several homes along the shoreline, surrounded by trees, is captured from the water. The calm surface of the lake reflects the clear blue sky and lush greenery. Various docks and boats are visible near the water's edge.
Home in Chapin
4.88 out of 5 average rating, 34 reviews

Summerset The Heart of Lake Murray

StaceyRating, 5 stars7 months ago
We had a great weekend at this lovely lake house. Multiple outdoor areas to enjoy the water and the view! Loved the property and all it had to offer. Curt was a great host, as well!
Guest favorite
The exterior of a modern log home is visible by the water, surrounded by tall trees. A wooden fishing pier extends toward the water, leading to a sandy area with seating. The sky exhibits shades of purple and pink during sunset, creating a serene atmosphere.
Home in Summerton
4.97 out of 5 average rating, 147 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

DeannaRating, 5 stars1 week ago
Our stay at Stuart’s place was nothing short of amazing. Property was just as described and had absolutely everything you could think of. We have stayed at Santee for the last 5 years and Stuart’s place was by far the best! We look forward to staying here again!
Superhost
The exterior of a two-story house is displayed, featuring light siding and dark shutters. A two-car garage is visible, along with a manicured lawn and landscaping. The driveway is spacious, leading to the entrance, while additional homes are seen in the background.
Home in Summerville
4.69 out of 5 average rating, 103 reviews

Low Country Living by Low Country BNB

ErinRating, 5 stars2 weeks ago
I can't say enough good things about Iris and this place! They were extremely kind and helpful. Would recommend staying with them anytime you are in the area! I know we will be!
Superhost
A modern kitchen features stainless steel appliances, including a stove and dishwasher. White cabinetry contrasts with a textured tile backsplash in soft gray tones. A spacious island provides additional counter space, and natural light illuminates the space from nearby windows. Stairs lead to the upper level.
Condo in North Charleston
4.74 out of 5 average rating, 66 reviews

Tranquil Condo w/ Pond View

PhilRating, 5 stars2 weeks ago
The property more than met our needs and the host was very responsive. The floor plan is outstanding

Quick stats about vacation rentals in Santee

  • Total rentals

    20 properties

  • Nightly prices starting at

    $100 before taxes and fees

  • Total number of reviews

    170 reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Rentals with a pool

    20 properties have a pool

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

Frequently Asked Questions

  • Are there vacation rentals with a dedicated workspace in Santee?

    Yes! Work meets play with ease at over 10 vacation rentals in Santee featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • How much does it cost to stay in apartment rentals in Santee?

    Experience the best of Santee with our apartment rentals, starting at about $190 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Do apartment rentals in Santee have a gym?

    Absolutely! We offer over 10 apartment rentals with a gym in Santee. Enjoy a tailored experience with all the comforts you desire.

  • Do apartment rentals in Santee have wifi?

    Absolutely! We offer over 10 apartment rentals with wifi in Santee. Enjoy a tailored experience with all the comforts you desire.

  • Are there Santee apartment rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 10 apartment rentals with pools in Santee, available on Airbnb. Make a splash and soak up the sun in style!

  • Are there family-friendly apartment rentals in Santee?

    Santee has more than 10 family-friendly apartment rentals. Amenities on the property may include high chairs, travel cribs, or strollers.

Destinations to explore