Vacation rentals with lake access in Santee

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Popular amenities for Santee lake access rentals

Lake access house rentals

Top guest favorite
Home in Eutawville
5 out of 5 average rating, 12 reviews

Lake House at Lake Marion

HopeRating, 5 stars1 week ago
What a dream! Beautiful location. Amazing views of the lake. Sunrises and sunsets were spectacular. Clean home with everything you can think of to make your stay cozy and welcoming. Our girls getaway was perfect. And we will definitely make plans to stay again.
Top guest favorite
A serene view of a private dock extending into a calm lake, leading to a gazebo surrounded by lush green trees. Reflections of the trees are visible on the water's surface, enhancing the tranquil atmosphere of the lakefront setting.
Home in Irmo
4.98 out of 5 average rating, 60 reviews

Livin' the Lake Life! Home w/dock/gazebo-Sleeps 8

MaryRating, 5 stars4 days ago
The lake house was great. Everything was very clearly labeled, organized, and well thought out. Sara thought of everything. It was very comfortable, and check out was especially easy. It was so nice to not have to strip the beds, wash the towels, take the trash to the curb, etc that so many other airbnbs make you do.
Top guest favorite
A private dock extends over still waters, surrounded by lush greenery. The deck offers wooden railings and ample space for seating, providing views of boats secured in the distance. Reflections on the water enhance the serene atmosphere of the lakeside setting.
Home in Chapin
5 out of 5 average rating, 25 reviews

The Lakeside Haven

RubyRating, 5 stars1 week ago
Me and my family had stayed here before right after the hurricane in October of 2024. Not much has changed since then, which is amazing! Dan and Linda are the sweetest hosts and an amazing couple! We definitely can't wait to stay again and enjoy the water once more.
Guest favorite
An aerial view captures the property layout along Lake Moultrie. A dock extends into the water, surrounded by lush greenery and trees. The home and additional buildings are visible, highlighting the spacious lawn and natural surroundings.
Home in Bonneau
4.91 out of 5 average rating, 32 reviews

Hideaway on Lake front for 7 guests

MasaRating, 5 stars3 weeks ago
Very clean and spacious house with more than reasonable stocked items made us feel at home the minute we stepped in. Inside, tasteful furnitures and decoration gave us a cozy feel as if we are staying at my grandmother’s house. Outside, you can spend all day relaxed with the sounds of nature - water, wind, and birds. I tried kayaking for the first time. Water is calm, nothing else is around me except water. What a soothing experience! And the sunset is breathtaking.
Superhost
A wooden dock extends into the calm water, leading to a viewing platform at the end. Green grass borders the shore, and the sky is filled with fluffy white clouds, creating a serene backdrop for the tranquil lake scene.
Home in Manning
4.86 out of 5 average rating, 7 reviews

Cozy 3 bed 2 bath waterfront lake house

KissahRating, 5 stars3 weeks ago
The host was great and the place was as described. We had enough space for everyone to sleep. I wish we had more time to enjoy the water but our schedule did not allow.
Guest favorite
Home in Chapin
4.91 out of 5 average rating, 81 reviews

Casa Azul - Lake Murray - Close in - Spa like bath

ScottRating, 5 stars8 months ago
We enjoyed our week at the lake and found the home well-stocked. We ate most of our meals at home and had everything we needed. The kitchen was nicely appointed, and the appliances were high quality. There is a Publix grocery store 10 minutes away and several local restaurants to enjoy. We used the charcoal grill for several meals and sat outside as much as possible. The whole family enjoyed the kayaks, paddle boards, canoes, and swimming in the lake. A ladder on the dock would make it easier to get out of the lake, but we made due.
Guest favorite
A wooden dock extends over still waters, showcasing a tranquil lakefront scene. An umbrella provides shade, while lush green trees surround the area, reflecting gently on the water's surface. Several boats can be seen nearby, highlighting the access to recreational activities.
Home in Manning
4.88 out of 5 average rating, 48 reviews

Cozy Church Branch Cabin

BarbaraRating, 5 stars5 days ago
The cabin is very cozy. We felt at home the moment we walked in. Morning coffee and evening cocktails on the deck overlooking the water was amazing. Catelyn thought of everything. Fully equipped kitchen and plenty of towels in the bathrooms.
Guest favorite
A scenic view of a lake house property set against a backdrop of dense trees. The main house is visible, featuring a covered deck and large windows. A dock extends into the lake, with a boat house positioned to the left, enhancing the outdoor setting.
Home in Chapin
4.86 out of 5 average rating, 71 reviews

Best View on Lake Murray located in Chapin SC

KimRating, 5 stars3 weeks ago
My husband and his friends have stayed multiple times at Chris's house and love it. Great location and love the house. Perfect location for their annual spring fishing trip. Chris is always quick to respond and help in any way. Thank you for sharing your home! Kim Cash

Lake access apartment rentals

Guest favorite
A serene lakeside view features colorful Adirondack chairs positioned on a grassy area. The sun sets in the background, casting warm hues over the water. Large trees provide shade, enhancing the peaceful atmosphere of the outdoor space.
Apartment in Moncks Corner
4.79 out of 5 average rating, 14 reviews

Ophir Oasis Unit #1

LeeRating, 5 stars2 weeks ago
Not my first time here, great place, frank is a great host. On top of everything, answers whenever you need him. See you next time, Frank.
Top guest favorite
Apartment in Chapin
5 out of 5 average rating, 14 reviews

Luxe Lakefront Apartment w/ Shared Pool & Dock!

AnielaRating, 5 stars5 months ago
Jeff and Elizabeth are great hosts! They made us feel incredibly welcome from the moment we walked through the door. They made fresh bread and had it waiting for us, along with an invite to a community event. Elizabeth and Jeff are lovely people and made us feel right at home. My teenage son told me to definitely book with them again next time I’m in town.
Guest favorite
Apartment in Gilbert
4.98 out of 5 average rating, 42 reviews

Lakefront Luxury Apartment ~ Lake Murray by Marina

JessicaRating, 5 stars3 days ago
We booked a last minute stay because we were in town for a funeral..Mark & Ruth were very accommodating. As for cleanliness probably one of the cleanest places I’ve stayed..the beds super comfy & just the best hosts! I hope we can come back again some time for a more relaxing reason :)
Guest favorite
An outdoor balcony features a dining table surrounded by four mesh chairs. A ceiling fan is visible above, and the view includes a serene lake framed by trees under a clear blue sky.
Apartment in Santee
5 out of 5 average rating, 5 reviews

Relaxation is the plan

TInaRating, 5 stars2 weeks ago
We stayed for one night on our trip from FL to PA to take a break from traveling. I wish we would have had more days to stay. The location right off of I-95 next to the lake was so refreshing. Everything was just as described , super clean and decorated nicely. I accidently left a necklace there and they communicated with me immediately and had it in the mail with tracking the same day. We would definitely stay here again !!
Top guest favorite
A serene lakeside view captures a colorful sunset sky reflecting on calm waters. A fountain gently spouts in the distance, while wooden docks and metal chairs are visible in the foreground, creating a peaceful ambiance for relaxation.
Apartment in North Charleston
5 out of 5 average rating, 8 reviews

Rest & Ripples

BillieRating, 5 stars1 week ago
The place is beautiful. The patio was wonderful for relaxing and morning coffee. the layout of the home is amazing for a group with everything spacious and spread out and having individual bathrooms!
Guest favorite
A single-story building features a light-colored exterior with a metal roof and an attached carport. The adjacent area includes a small outdoor seating arrangement with four chairs surrounding a table, situated on a well-maintained lawn with tall grass.
Apartment in Pineville
5 out of 5 average rating, 7 reviews

Our Place at the Lake.

SusanRating, 5 stars6 months ago
Perfect place to unplug and relax for the weekend. Fire pit was fantastic and the outside table was a great place to sit enjoy the perfect weather.
The three-story brick property is situated along Lake Murray, featuring a striking blue metal roof. Lush green landscaping surrounds the home, which includes multiple balconies and a spacious front yard. A boat is moored nearby, providing easy access to the water.
Apartment in Irmo
4.91 out of 5 average rating, 22 reviews

Large 1 bedroom apt/boat ramp &dock on Lake Murray

AprilRating, 5 stars8 months ago
It was very comfortable and homey. Quick drive to Columbia, very peaceful to come back to and relax after exploring. Beautiful view of Lake Murray with plenty to do and stores very close by. The hosts were very accommodating. They had refreshments, snacks, and basic necessities needed. Would highly recommend and would stay at again. ….thank you very much!!!!!!!

Lake access cottage rentals

Guest favorite
A wooden dock extends over calm waters, leading to a spacious green lawn surrounded by trees. A screened-in porch with seating is visible in the background, providing a relaxing space to enjoy the tranquil lakeside atmosphere.
Cottage in Chapin
4.93 out of 5 average rating, 86 reviews

Waterfront Cottage on Lake Murray w/private dock

RogerRating, 5 stars3 months ago
The Sandbar Cottage was everything we wanted it to be. Candy was very responsive before our visit answering any questions that I had about the location and stay. During our visit she was super responsive as well, allowing me to modify and stay a bit lengthier than we had planned. We traveled as a couple, with our two dogs and bass boat. The accommodations for all were great and just has had been explained. The pet area was super convenient and on the property boat ramp worked out great for us. I recommend getting there in daylight the first day just to take a look around as to how you need to pull in for the ramp and such, my outfit is around 50’ total length. We were able to get settled in make great use of all. I can’t say enough how comfortable the cottage was and warming atmosphere. The first two days of our stay the weather didn’t cooperate. But the cottage was set up with a warm Christmas appearance and the open porch leading to a fenced in area was great for our pups.
Top guest favorite
Cottage in Columbia
4.97 out of 5 average rating, 510 reviews

The Historic Selwood Cottage @theselwoodcottage

DeannaRating, 5 stars2 days ago
Highly recommend! Needed a place to stay on my trip home from the Blue Ridge Mountains and this was perfect. The place was absolutely adorable and very clean. The neighborhood is quiet and peaceful and within close proximity to many restaurants. Would definitely stay again!
Top guest favorite
A cozy living area features large windows providing views of the waterfront. A plush sofa and swivel chair are arranged around a coffee table, with a flat-screen TV visible on a stylish media console. A sleek granite countertop is positioned at the kitchen's edge.
Cottage in Chapin
4.97 out of 5 average rating, 150 reviews

Gamecock Cottage @ Lake Murray-Waterfront w/ Dock

CaitlinRating, 5 stars3 days ago
This is one of our favorite places to spend a weekend on Lake Murray! It’s such a comfortable space with an incredible view and we enjoyed spending the day enjoying the lake and relaxing. The cottage has everything you could possibly need, and the check in was so easy. The hosts were kind and accommodating and we will definitely be back! Grocery store is only 5 minutes away if you need to grab anything on the way in. If you’re looking for the perfect lakefront getaway—This is it!!!
Superhost
A cozy living room is depicted with neutral-toned walls and soft carpeting. A green-patterned sofa is complemented by a textured armchair, while a light-colored coffee table sits at the center. A floor lamp provides warm lighting, and decorative elements include wall art and potted plants.
Cottage in Summerton
4.61 out of 5 average rating, 99 reviews

The Fish House

DawnRating, 5 stars34 months ago
Great place to stay with dock access. We enjoyed ourselves and had a wonderful weekend. Everyone in the neighborhood was very polite and kind. My family would love to spend time here again. Kayaking from the boat ramp was a bonus.
Guest favorite
The exterior of the lake cottage is shown, featuring a screened porch with multiple windows. A grassy lawn surrounds the home, with a few trees in the background. A wooden deck and steps lead away from the cottage, providing access to the outdoor area.
Cottage in Prosperity
4.92 out of 5 average rating, 36 reviews

Private cottage w/a view, Dock, SUPs, Kayaks

LourdesRating, 5 stars3 months ago
We had an amazing stay at this beautiful place located right in front of a stunning lake! The views were absolutely breathtaking and made our time there so peaceful and refreshing. Lauren was incredibly responsive and made sure we had everything we needed during our stay. She also provided a great list of nearby places to visit, which was super helpful for exploring the area. The little touches really made a difference – there was coffee, spices, and even games to enjoy, which added to the cozy, home-like feel of the space. Plus, the place is very kid and pet-friendly, which was perfect for our family. We truly loved our stay and would highly recommend this spot to anyone looking for a relaxing getaway!
Top guest favorite
A view of Lake Murray is framed by tall pines, with a wooden dock extending into the water. A stone firepit is positioned on the shore, providing a gathering spot. The cloudy sky adds a calming atmosphere to the lakeside setting.
Cottage in Lexington County
4.94 out of 5 average rating, 52 reviews

Entire Cottage on Lake Murray

ChristopherRating, 5 stars2 weeks ago
We had a very pleasant stay at Sheri's place. We were fishing a tournament out of Dreher Island and this location was perfect for launching our boat and driving to the ramp by water. It was a very quiet and peaceful area. Sheri was very helpful with her knowledge of this location. She even went as far as helping me locate the exact type of oil needed for my motor. If you are looking for a place to stay with a really nice view of the lake with a ramp and dock this place is where you will find it.
Guest favorite
A wooden deck offers a clear view of the serene canal, surrounded by lush greenery and scattered trees. Sunlight filters through the branches, casting playful shadows on the deck. A canoe can be seen gently floating on the water, adding to the peaceful scene.
Cottage in Bonneau
5 out of 5 average rating, 19 reviews

Three Little Birds Canal Cottage

JodiRating, 5 stars1 month ago
Our whole family loved the stay at Kim and Lee’s home. Such a beautiful location and a lovely house! The house is clean and stocked with everything you could ask for, the beds and furniture are very comfortable, and the view from the backyard is beautiful. Even our pets loved sitting in the sun and watching the animals outside! Very much a perfect stay and great hosts.
Top guest favorite
An aerial view of a waterfront property showcases the private dock extending into Lake Moultrie, surrounded by lush greenery. The cabin and neighboring structures are visible in the background, framed by tall trees and open spaces, emphasizing the serene lakeside environment.
Cottage in Bonneau
4.95 out of 5 average rating, 194 reviews

Relax at the Lakehouse with a dock

MarciaRating, 5 stars2 weeks ago
Michael is A+ host ! He was super helpful with instructions as well as things to know about the house & the area.

Quick stats about vacation rentals with lake access in Santee

  • Total rentals

    20 properties

  • Nightly prices starting at

    $100 before taxes and fees

  • Total number of reviews

    40 reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Rentals with a pool

    10 properties have a pool

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

Destinations to explore