
Panacea vacation rentals
Book unique vacation rentals, houses, and more on Airbnb
Top-rated vacation rentals in Panacea
Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panacea vacation rentals
Panacea beach vacation rentals

*Beach House w TIKI BAR*
Great house! Easy walk to public beach access.

April 26 - May 3 is ON SALE! 1st Tier-Private Pool
One level. Split masters, beach path as shown. Always stayed in the Plantation, pleasantly surprised with close proximity to everything.

Oceanfront | 2 Balconies | BONUS $150/day | Dog-Fr
The Airbnb was nice, clean and organized with a great view of the ocean. My kids loved the arcade games and had so much fun at the beach. We loved watching the sunrise and sunset from the balcony. We enjoyed the easy access to the beach. Alexandra was so responsive and gave us some nice recommendations around the area.

100 STEPS TO THE GULF-CONTEMPORARY-SOARING CEILING
Our family had a great time at Molcie's. The location is very conveniently located near the beach. It takes no time at all to get there by foot, even while carrying beach chairs and pulling a wagon. The place was as described and checking in/out was a breeze. I love that she allowed us to bring our fur babies for an extremely fairly priced dog fee. We will be back!

Family Tree
Beautiful home. We loved all the marine life we were able to find. The only complaints we had was there wasn’t a grill and the pool not being in the neighborhood. Overall a great week. Would definitely recommend.

Walk to Beach & Attractions! Remodeled & Spacious
Ruth is a wonderful host, very responsive, kind and helpful with any questions you have about Saint George. It’s a beautiful place especially if you are looking to be in walking distance of restaurants, shopping, and other family attractions. The rentals are walking distance too. It is above a Subway, which I didn’t mind and neither did my kids that were down there everyday we were there. Lol! The management there was very nice upon arrival letting us know if there was anything we needed to let them know which was very kind. It’s very quiet at night. We enjoyed our stay and recommend.

CR Beach
We had a wonderful family vacation on St. George Island. The kitchen and common areas were great. We were able to have meals together, play games, and watch the Olympics. We had the beach to ourselves! The pool was right out the back door!

Shell Point Beach 2BR condo | Balcony views
It was a lovely place.
House rentals in Panacea

Beautiful home with room for the entire family!
This was a nice home for my family to visit FSU for my upcoming Freshman. Neighborhood was very quiet and clean. Very close to the school than I expected. Home had everything you need with little to nothing to add during your stay. Definitely first in an Airbnb home to have everything available from towels to remove makeup to spices to make your favorite meal along with bakeware and dishes. Would recommend and will consider staying here again when visiting my daughter in school.

Intimate 3/3 by FSU, FAMU, & downtown Tallahassee
We were in town for a wedding, the home was welcoming, within walking distance of the venue, very clean with a pretty backyard. If we were to come to the area again we would definitely rebook.

My House, Your House
SPECIAL Thanks to JENN! I am deployed to Tallahassee for work and Jenns's place made me feel comfortable, safe at home, and relaxed after a 10hr work day. The home is just as pictured. My furbaby enjoyed the private fenced backyard. And there's a safe walking path right across the street; which I loved! Jenn"s communication is TOP notch. She's very responsive and accommodating. I have already rebooked. THANK YOU JENN!

Quiet Cul de sac;1mile I-10;6 miles FSU; 6.5 FAMU.
Great price for the money, particular for dog owners. Henry was very responsive even on a holiday weekend. Plenty of space, comfortable, quiet safe neighborhood, good internet speeds. Loved being close to FSU for our student. Starting to show wear due to consistent rentals but overall great.

Brand NEW House-.5Mi to FSU/1.6Mi to FAMU
Very happy with my stay here! The nightly rate is a great value considering the location and everything provided in the house. Ameer and Tacorra answered messages quickly and seem like awesome people. Ameer and the house definitely exceeded expectations.

3 Bedroom Trendy Elegant Vibe close to Colleges
Stayed the weekend for a soccer tournament. A very short 2 minute commute to our soccer fields. Great house, very cozy and comfortable. All kids had their own beds and weren’t climbing into ours. We had a great weekend and loved our stay.

Tranquility Meets Convenience
Our crew of four had a comfortable stay. There is plenty of space and they want me to reserve it again as we have work in the area.

Modern Luxury House with Prime Time Convenience
We had the pleasure of staying at Anthony's Airbnb home in Tallahassee during our company's team offsite. Despite a minor address mix-up (quickly resolved by the host), the house matched the pictures exactly. Its location was within walking distance of the downtown core, Saturday Farmer's Market, and Cascades Park. It spans three floors and has two staircases. There are no carpet runners, which is something to consider for anyone traveling with young children or older family members. Although we didn't use the hot tub, the host had thoughtfully removed its cover. I recommend this clean, modern & conveniently located home for anyone visiting Tallahassee.
Beach house rentals in Panacea

Face in the Wind
The house was in near new condition and very well appointed with everything needed and more. The location is a short walk to beach access and is located on the bike/walk path. Our group loves the area and Patrick's place was perfect and super clean. Patrick was a great communicator and we appreciated that so much. I highly recommend to other guests.

Pure Bliss
Shelbey’s place was beautiful. The beach was so calm and perfect for the little kids to play in. It was the perfect place for a relaxing vacation. Any time we had a question Shelbey was very quick to respond and she was very accommodating. We will definitely be coming back!

Tucked Away Private Beachfront Home
Beautiful home on private beach. Our second time here. Highly recommend for a peaceful beach getaway

Oceanview, Private beach in gated community
This is our 2nd time staying at Zenghai’s place and we enjoyed it as much as the first time. This visit, we were 3 couples, so each couple had a private room + bath. Importantly, the kitchen was well-equipped and the DR had a large table, which worked well for group meals. The house was spotless and the beach, a short walk away, was lovely. Hope to return again!

Cozy coastal cottage w/pool and dogs are welcome!
We loved our trip to Summer Camp. The house was beautiful and comfortable. Our host was very responsive and helpful. The location is amazing if you are looking for a sense of seclusion and relaxation. The screened back porch and private backyard space are wonderful. The beach is natural and seems like a private oasis. The kids enjoyed the shallow water and finding a variety of marine life. St. George Island is beautiful and close by as well as the aquarium and several cute small towns. Angelo’s Seafood is a wonderful place for delicious seafood and steaks. Wonderful vacation. Will definitely return.

Reel Paradise beachfront House
Saw lots of sea life - dolphins, pelicans, sea gulls, otter, herons, eagles. We saw the dolphins swarming the fish. Awesome sight. Lots of deer in the park across the road. Plenty of privacy. House very spacious - plenty of storage areas. Lots of windows for viewing the gulf activity. Great deck.

Direct beachfront private luxury villa Sea La Vie
We were looking for a quiet place to enjoy widlife, sea, sun and beach with our 2 boys and we found Marcin's Sea La Vie House. That's was a perfect match. This house is very nice, well maintained, well equipped and well organized. I could spend all my time taking pictures of Dolphins and birds from the wonderful porch. We enjoyed being there and we will certainly be back.

Eastpoint on the Bay- Private Beach, Pool, Sunsets
What a wonderful place to create lifelong memories with family and friends! The home was very spacious and was furnished with almost everything you need for your stay! Our family throughly enjoyed our time!
Quick stats about vacation rentals in Panacea
Total rentals
20 properties
Nightly prices starting at
$80 before taxes and fees
Total number of reviews
790 reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Wifi availability
20 properties include access to wifi
Frequently Asked Questions
Are there pet-friendly vacation rentals in Panacea?
Four-legged friends are welcome in Panacea. Choose from more than 10 vacation rentals for guests traveling with pets.
How much does it cost to stay in hotel rentals in Panacea?
Experience the best of Panacea with our hotel rentals, starting at about $150 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Destinations to explore
- Panama City Beach Vacation rentals
- Destin Vacation rentals
- Florida Panhandle Vacation rentals
- Seminole Vacation rentals
- Tampa Vacation rentals
- St Petersburg Vacation rentals
- Tampa Bay Vacation rentals
- Saint Johns River Vacation rentals
- Four Corners Vacation rentals
- Central Florida Vacation rentals
- Orlando Vacation rentals
- Kissimmee Vacation rentals
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes