House vacation rentals in Orangeburg

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Top-rated house rentals in Orangeburg

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Guest favorite

An aerial view captures a diverse neighborhood with a mix of homes, showcasing various roof colors and styles. Lush greenery surrounds the buildings, while tree canopies provide natural shade. Streets are low-traffic, enhancing the tranquil residential setting.

Home in North Charleston

4.95 out of 5 average rating, 118 reviews

Charming, bright, modern home near Park Circle

Our home is a completely remodeled gem in the midst of an older, quiet neighborhood in N. Charleston. It really sparkles with new granite countertops, appliances, washer/dryer, tankless water heater and more! Brand-new king and queen beds; new top-of-the-line automatic air mattress. • 21 mins to beach (Sullivan's Island) • 13 mins to downtown • 9 mins to Park Circle • 10 mins to Riverfront Park • 9 mins to airport • 9 mins to Tanger outlets Perfect for couples, families, traveling nurses, etc

Top guest favorite

A hallway connects an inviting living space to an open kitchen and dining area. Exposed wooden beams line the ceiling, adding character. A comfortable sofa with cushions is positioned beside a wooden coffee table, while a guitar rests against the wall, highlighting a welcoming atmosphere.

Home in Park Circle

4.97 out of 5 average rating, 140 reviews

Nordic Haus: Modern and Peaceful Central Location

Welcome to our beautifully renovated home located right above downtown Charleston in desirable neighborhood of Park Circle. A fully equipped kitchen with all amnesties to cook for friends and family. A kitchen island with 6 seats and a spacious living room with 75” TV is waiting for you. The beds are of the highest quality and the bathrooms are designed luxuriously. A Scandinavian inspired home with games to bond! Enjoy a lively dining and nightlife scene! Walk to the US-largest kids playground

Guest favorite

Home in North Charleston

4.97 out of 5 average rating, 118 reviews

Hobson House ~ 15min to DT ~ Game Room ~ Fire Pit

Home and neighborhood are featured in Netflix’s Hit Show Outer Banks Season 4. House is a Historic (1940's) 2 story 4000 sq ft, 5 BR (7 beds), 2.5 BA Panama House. Located in the former Naval Officers Quarters within walking distance to Riverfront Park + a short drive to Park Circle restaurants. 10 min to airport, 15 to dwtn, 25 to beaches. Very private; giant oaks and plenty of space for a wonderful stay with friends and family. City of North Charleston Short - term rental permit 2025-0077

Guest favorite

Home in Park Circle

4.85 out of 5 average rating, 136 reviews

Walk to Playground & Dining|Game Room|Pet Friendly

Across the street from the largest adaptive playground in the US and a frisbee golf course - an incredible location and home for families. This charming, park-front home sits on a quiet street under a beautiful live oak tree in the heart of Park Circle. Plenty of play space for the kids in the game room and bunk room, while the adults can relax in the backyard or rest of the cozy home. A short walk to restaurants, only 15 min drive to Historic Downtown Charleston, and 20 minutes to the beaches.

Guest favorite

A bright entryway features light blue walls complemented by white wainscoting. Plantation shutters allow natural light to enter, while a decorative mirror and framed coral prints adorn the walls. A stylish chandelier provides additional illumination, enhancing the welcoming atmosphere of the space.

Home in Park Circle

4.96 out of 5 average rating, 122 reviews

Kappi’s Luxury Coastal Retreat

This beautiful modern 2210 sqft house is blocks away from breweries, restaurants/bars, wine shops, and shopping of downtown Park Circle. It is a 8 minute walk to Firefly Distillery (home of Sweet Tea Vodka) and Holy City Brewery! The home is centrally located and is 8 miles to historic downtown Charleston, 16 miles to the beaches of Sullivan’s Island, and 5 minutes from Top Golf and Coliseum! You’ll love the outdoor space, which is complete with two seating areas, pergola and a gas grill!

Guest favorite

A comfortable living space features a black leather sofa draped with a soft throw blanket. A round black coffee table with gold accents is positioned in front of the seating. A tan armchair completes the arrangement, set against soft beige carpet and light gray walls.

Home in Cayce

4.91 out of 5 average rating, 145 reviews

Columbia’s Best Airbnb

Take it easy at this unique and tranquil getaway. Our Airbnbs are the nicest in each town. From our known luxurious mattresses to the best kept secret… 3D luxury digital Massage chairs relax you from any stressful situation. See why we are ambassador Airbnb host. Stay at this location and you are 5 to 10 minutes to the USC baseball, basketball and Football. Campus is same. Airport is 4 miles. Great kid activity at EdAdventure kid museum. I 26, I-77 and downtown Columbia are minutes away. G

Top guest favorite

A charming blue house showcases a welcoming front porch with white railings. Lush greenery surrounds the home, enhancing its inviting facade. The yellow door adds a pop of color, while well-maintained landscaping provides a pleasant entrance.

Home in Sumter

4.97 out of 5 average rating, 115 reviews

The Parkside Retreat

Welcome to our beautiful Airbnb! Located next to a serene and picturesque park, our home is perfect for families or groups looking for a comfortable stay. With two king master suites and a cozy kids room, we can accommodate up to 6 guests, making it an ideal choice for a family or a group getaway. Each master suite features a comfortable king-sized bed, plush linens, and ample storage space providing a tranquil retreat after a day of exploring the local attractions. Book your stay today!

Guest favorite

A spacious living area features large windows providing ample natural light. Comfortable seating arrangements include a grey sofa, an orange accent chair, and patterned chairs. A coffee table is placed centrally on a soft rug. The open concept allows for visibility of the kitchen area in the background.

Home in Lexington

4.97 out of 5 average rating, 154 reviews

Lakefront home on Lake Murray with private dock

Lakefront home on Lake Murray in Lexington, SC on over 1/2 an acre, 166 feet of waterfront with deep water, private dock, and entertainment space- perfect for an unforgettable vacation or weekend. Entire home for rent-4BR, 3 Bath +2 half baths, 2 sofa sleepers, sleeps 12. Breathtaking kitchen & large living space, perfect for the entire family. 2 single person kayaks, outdoor grill, 65 inch and 55 inch TV, washer/dryer, and fast wifi. Master suite with a lavish bathroom and soaking tub.

Guest favorite

A fire pit surrounded by several dark chairs is set on a grassy area by the water's edge. The calm lake reflects the trees and distant docks, creating a serene lakeside environment. A few boats can be seen anchored along the shore.

Home in Ridgeway

4.97 out of 5 average rating, 105 reviews

Hillside Haven on Lake Wateree- Entire House

Lake Wateree rental with 3 bedrooms, 2 bathrooms that will comfortably sleep 10 guests. It is located in Ridgeway, SC and less than 5 minutes to Buck Hill Landing. Upstairs, you will find a fully stocked kitchen, living\dining room and master bedroom. Downstairs, there is a second living area with second kitchen, bathroom and 2 bedrooms. Home includes private deep water dock. Perfect location for swimming, kayaking and fishing. Fire pit is perfect for cool fall nights. Book it today!

Guest favorite

A spacious living area features wood-paneled walls and high ceilings, showcasing a stone fireplace as a focal point. Comfortable seating arrangements are provided, along with a television positioned above the mantel. A dining area is visible through large windows, inviting natural light.

Home in Summerton

4.97 out of 5 average rating, 147 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Guest favorite

A wooden dock extends from the grassy shoreline, leading to a calm cove. The water reflects the clear blue sky, with nearby boats moored at floating docks. Lined with trees, the scene offers a serene setting for relaxation and lake activities.

Home in Irmo

4.87 out of 5 average rating, 106 reviews

Lakefront w pool, dock and pool table, sleeps12

Location, location, location! 10 minutes to Lexington, 15 minutes to Chapin, 15 minutes to downtown Columbia, 8 minutes to Harbison shopping. Boat parking at the dock. No need to pay high docking fees. Gorgeous sunsets, calm cove. Swim in the lake or relax by the pool. The massive deck is great for family fun or unforgettable events with your friends. Close to Liberty’s /Lake Murray marina on the lake, and Cat Fish Johnnys/rusty anchor marina. Not your typical Lake Murray Airbnb!

Superhost

A welcoming living area features a large sectional couch and a dark wood coffee table centered on a textured area rug. Natural light flows in through large windows, complementing the neutral wall tones. A flat-screen TV is mounted on the wall opposite the seating.

Home in Ladson

4.9 out of 5 average rating, 166 reviews

Charleston HotTub FirePit FirePlace Patio Hammock

👍PRIME CENTRALIZED LOCATION to explore all Charleston has to Offer! ✅ NO Cleaning Fees! ✅ 2 mins to Summerville Medical Center ✅ Featured in Relative Race Reality TV show! ✅ 10 mins from I26 ✅ 35 mins from downtown Charleston and beaches🏖 ✅ 18 mins to Airport/Convention Center/Performing Arts ✅ 3 mins to Publix Grocery/restaurants ✅ Hot Tub 💦 ✅ Fire🔥Pit ✅ BBQ 🍔 Grill ✅ Fire🔥Place ✅ Hammock 🌴 ✅ High Chair & Pack n Play 🍼 ✅ Air Hockey Table 🏒 ✅ K Cup/Coffee Pot ✅ EV plug