House vacation rentals in Isle of Palms

Find and book unique houses on Airbnb

Top-rated house rentals in Isle of Palms

Guests agree: these houses are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Top guest favorite

An open living area features a rustic wooden ceiling and a spacious layout. A large television is mounted above a green sideboard alongside a potted plant. Natural light floods the space through wide windows, leading to a dining area visible in the background.

Home in Mount Pleasant

5 out of 5 average rating, 111 reviews

Rockin’ Robin - Family sized great location!

Beautifully designed Open Floor plan 5 Bedroom/ 4.5 Bathroom home that is in an incredible location. So Close to everything! Each Room has a Comfortable Queen bed and only Two Rooms share a bathroom. Every other Room has their own En-Suite. Large Chefs Kitchen that is open to the other areas of the home for socializing. Great Man cave in the Garage with Lots of games. Relax in the Great room with Big windows for Natural Light TOMP STR Permit No. ST250034 Mt Pleasant Business License #20107744

Superhost

An outdoor gazebo offers a cozy seating area with a swing couch adorned with colorful pillows. A wooden bar with seating is attached to the structure, featuring a TV mounted on the wall. Lush greenery and patterned tile flooring enhance the inviting space.

Home in Mount Pleasant

4.95 out of 5 average rating, 104 reviews

Old Village Getaway Near the Beaches!

Newly renovated three-bedroom home in quiet neighborhood. Bright windows & french doors throughout the house. Sunroom off of the kitchen adds lots of brightness! Entertainment Gazebo out back for dinner or movie or both! Hot tub/spa w/outdoor shower. Located 2 mi. from Sullivan's Island beach, 1 mi. from Shem Creek & 5 mi. from downtown Charleston! This is not a party house - no parties, party groups or outside guests allowed. STR PERMIT #: ST240352 EXP: 12/31/25 SC BUS. LIC. #: 20122379

Top guest favorite

Home in Folly Beach

4.96 out of 5 average rating, 174 reviews

Lux Beach Bungalow Ocean Views Heated Pool

Relax on the beach. Shower outside. Sip cocktails on one of the porches with beach views. Grill out by the pool. Take a stroll to dinner and enjoy some live music with friends and family. Luxury furnishings and linens. Stay in a home not just an Airbnb. One block from Center Street, you are walking distance to shops, restaurants, bars, the pier, and Bert's corner market. This comes in very helpful as this area is nearly impossible to find parking. Front door to the sand is <300ft. LIC 007914

Guest favorite

An outdoor entertainment area featuring a spacious patio with a large wooden table surrounded by colorful chairs. Lounge chairs are arranged in a row over vibrant green turf. A grill is positioned under a wooden pergola, providing a cozy setting for gatherings.

Home in Isle of Palms

4.93 out of 5 average rating, 100 reviews

Steps from the beach: extraordinary home and yard

-The beach a few steps away: wander down just 300ft and you will feel sand on your toes or just relax in the hot tub -Outdoor living: Achieving the indoor/outdoor lifestyle isn't exactly easy but this house does it! Perfect for lounging, lazy afternoons and outdoor dinner. In the colder month enjoy the fire pit, smores time anyone? - Additional attached apartment can be added for more space and comfort -Idyllic family escape: It displays charm, character, and luxurious comforts for all ages

Guest favorite

An airy kitchen and dining area is shown, featuring light-colored cabinets and a large wooden dining table surrounded by six chairs. A comfortable sofa with patterned pillows is visible in the foreground. Natural light enters through a large arched window above the sink.

Home in Folly Beach

4.94 out of 5 average rating, 126 reviews

Beautiful Beach House. Outstanding Location.

Beautiful Beach House. Sleeps 8. Outstanding location. 3 bedroom, 2 bath beach house offering a view of the ocean. Access to the beach is directly across the street. Less than 200 feet to the ocean. Large great room and large dining area. Amenities include high speed wireless internet, 65" HDTV in the living room, Central AC, washer and dryer, full kitchen.1 king, 1 queen, 2 doubles, sleeper sofa. Outdoor shower to rinse off after a day at the beach. SC Business License: LIC-2-19-202662

Guest favorite

Home in Mount Pleasant

4.93 out of 5 average rating, 154 reviews

Lowcountry Lux / 5 min to Beach / 7 min to Dtwn

Luxurious & comfortable home located in Mt. Pleasant; located walking distance to a grocery store, a mile from Shem Creek w/ several new chic restaurants, a 2-min ride to restaurants & shops, 5-min to the nearby beach on Sullivan's Island, and 10 minute drive to downtown Charleston. You will feel right at home in this luxurious 3-story home with a brand new 82" TV, a WFH area, BBQ grill, & outdoor seating area. Come experience lux modern beach living and all Charleston has to offer!

Guest favorite

A bright living area features a spacious sofa centered against a wall with two mirrors. Two gray accent chairs flank a coffee table, with a vase of flowers providing a touch of color. Natural light streams in through the window, illuminating the hardwood floor and area rug.

Home in Mount Pleasant

4.89 out of 5 average rating, 481 reviews

Beach+Downtown ★Walkable Old Village Luxury Style2

Best of Both worlds--3 minutes to Downtown Charleston & Sullivan's Island Beach! Mt Pleasant is Rated the Best Place to Live in SC! Enjoy Downtown Mt Pleasant Amenities. Old Mt. Pleasant in a Marsh-front Community. Beautiful 100 year-old Oak Trees! Walk to Shem Creek Restaurants & Marina, Steps to Old Village, Grocery stores, coffee shops, shopping, Red Drum Gastro Pub, New Mt P. Farmers Market. Relax in wonderful large private backyard under tree canopy. ST250064 BL: 20123990

Superhost

A welcoming living area features a large sectional couch and a dark wood coffee table centered on a textured area rug. Natural light flows in through large windows, complementing the neutral wall tones. A flat-screen TV is mounted on the wall opposite the seating.

Home in Ladson

4.9 out of 5 average rating, 166 reviews

Charleston HotTub FirePit FirePlace Patio Hammock

👍PRIME CENTRALIZED LOCATION to explore all Charleston has to Offer! ✅ NO Cleaning Fees! ✅ 2 mins to Summerville Medical Center ✅ Featured in Relative Race Reality TV show! ✅ 10 mins from I26 ✅ 35 mins from downtown Charleston and beaches🏖 ✅ 18 mins to Airport/Convention Center/Performing Arts ✅ 3 mins to Publix Grocery/restaurants ✅ Hot Tub 💦 ✅ Fire🔥Pit ✅ BBQ 🍔 Grill ✅ Fire🔥Place ✅ Hammock 🌴 ✅ High Chair & Pack n Play 🍼 ✅ Air Hockey Table 🏒 ✅ K Cup/Coffee Pot ✅ EV plug

Guest favorite

The living room features a spacious white sofa adorned with colorful cushions, a wooden coffee table, and a textured area rug. Light enters through large windows, illuminating the open space, which transitions to a dining area visible through an archway.

Home in Isle of Palms

4.91 out of 5 average rating, 119 reviews

Amazing Location, across the st. from the beach!

Located directly across the st. from the beach, w/public access! Fully fenced, pet friendly. 4 bd - sleeps 10 comfortably, 2.5 bths. Bright open airy design. Huge living room w/high vaulted ceilings. Eat-in kitchen & newer appliances. Formal dining rm w/lots of glass & great views. 3 front porches-1 screened. 3 Decks. French doors in up. bds lead to outdoor sitting areas. Close to awesome restaurants, shopping, food stores & so much more! ONLY WEEK LONG MIN STAYS IN SUMMER

Guest favorite

A light-filled living area features exposed wooden beams and a mix of cozy seating options, including a brown leather sofa and two blue velvet chairs. A wooden table sits at the center, accompanied by decorative items and plants. Art pieces adorn the walls, adding a touch of character.

Home in Cannonborough - Elliottborough

4.98 out of 5 average rating, 136 reviews

❤️ of Charleston - Luxurious & Rustic -Near King!

Completely Renovated House - 1block from King Street! (Brand New Listing! - Rare Find!) * 3 bedrooms +2 full bunk beds & 2 full bathrooms * Brand new Construction - Heavily insulated and quiet inside! * High End Kitchen! * Walk Score 98 ('Very Walkable') * 1 Block From King Street * Private Outdoor Piazza + Outdoor Terrace * Off Street Parking for 2 vehicles * Onsite washer's & dryer's * Safe neighborhood in awesome location - near all the best restaurants and bars!

Top guest favorite

The exterior of the three-story home showcases a modern architectural design with light-colored siding and contrasting trim. Large windows brighten the facade, and a wooden door is positioned at the entrance. Lush greenery lines the base, enhancing the home's appealing curbside view.

Home in Mount Pleasant

5 out of 5 average rating, 227 reviews

Upscale EARL CRT 3-bdrm Old Village/Shem Creek

STR PERMIT #ST250276 BUSINESS LICENSE #32844 3-bdrm Earl's Court neoclassical upscale home, nestled in the heart of the historic Old Village, offering the charm of low country living. Just a block from Shem Creek bars & restaurants, Old Village shops & eateries, Alhambra Hall, Pitt St Bridge, and a weekly all food Farmer's market, featuring low countries finest! The Arthur Ravenel Bridge, downtown Charleston, Sullivan's Island & IOP beaches are all bike riding distance.

Guest favorite

A cozy dining nook is featured, showcasing a blue upholstered bench with two coral pillows. A sleek silver table complements the rustic brick wall, while two pendant lights hang above, providing gentle illumination.

Home in Folly Beach

4.93 out of 5 average rating, 243 reviews

Folly Vacation 204 Getaway, Relax & Unwind

This unique Spanish-style 2 bedroom, 1 1/2 bath beach house is in a quiet residential area with an easy walk to all the restaurants, shops and the ocean. Respectfully renovated to maintain its historic integrity, you’ll appreciate the mix of old and new. Dog friendly with a one-time fee of $110 per dog up to 3 nights, and $150 per dog for 4 or more nights. Fee is added once your reservation is confirmed. Rental Registration Number STR22-00313

0 of 0 items showing

What guests are saying

Beautiful and spacious 5/3, near I95 /I 26.highway

4.83 out of 5 average rating, 6 reviews4 months ago

Laura was a wonderful host who went above and beyond to ensure we were comfortable and had all the amenities during our stay. She was very quick to respond and ensured any issue was handled quickly. I would certainly recommend her for anyone interested to book at her house. My family and I felt at home and really enjoyed our stay! Laura is a lovely lady!

Home in Summerville

What guests are saying

3BR House Minutes From the Beach and Downtown!

4.93 out of 5 average rating, 86 reviews2 weeks ago

We just returned from our stay at Paul’s place. The home is perfect. It’s close to many restaurants and things to do. The home itself is adorable and very well kept. They have literally thought of everything you may need. Paul was very responsive if we had questions. I would definitely stay here again if in the area and highly recommended if you’re looking for a great home while visiting the Charleston area. 😊

Home in Mount Pleasant

What guests are saying

Little Boho Beach House ( Oceanfront Rental)

4.87 out of 5 average rating, 46 reviews6 days ago

If you don’t want to fall into a deep sleep to the sound of ocean waves and a cool breeze, then waking to have coffee on the porch overlooking the beach, then I don’t recommend staying at Crissy’s cottage. Her cottage is perfection. The screened porch is comfy, the living room pretty and esthetic, and the bedrooms cozy and so comfortable. She is a very receptive hostess, she makes you feel right at home. If you can, pack fishing gear/tackle. Several of the locals loved sharing their tips and tricks with us.

Home in Edisto Island

What guests are saying

Modern, triple master, quiet

4.87 out of 5 average rating, 15 reviews10 months ago

West and East coast cousins get together for a beautiful stay on Kiawah Island. Three generations and we all loved the home and location. It was spacious enough that all ten of us felt comfortable. There were five adults and five children (infant through age 12). We cooked several meals during our stay and the kitchen was definitely designed for people who love to cook. We rented beach items and bikes through ESPM and enjoyed riding bikes to the beach (about a 10 minute ride) and on the many bike trails on the island. This was a lovely, spacious home. The screened in porch was a great place to sit, chat and enjoy the privacy of the back yard. The area was gorgeous, the house lovely and we would definitely reserve again.

Home in Kiawah Island

What guests are saying

FANTASTIC PRICE!! FOR CHARLESTON 2 BEDROOM HOUSE

4.95 out of 5 average rating, 216 reviews1 month ago

Tony's place was exactly what we needed. Very close to the Art Center, Coliseum and an Shopping Outlet. The host was very friendly, responsive and understanding. We appreciate the details he puts to have his guests feels at home. We love the background music when you first get to the house..... was a nice welcoming after a long drive.

Home in North Charleston

What guests are saying

Mount Pleasant Lake Haven. #ST240278. BL#20127571

4.96 out of 5 average rating, 92 reviews2 weeks ago

The house was perfect for us. We have 4 adult children and we all stayed and slept very comfortably. Beautiful home with everything you need. Very close to Sullivan Island, Shem Creek and downtown Charleston. I would definitely stay again. Thanks Natalia for sharing your home.

Home in Mount Pleasant

What guests are saying

Exquisite Newly Built 2204 sq ft End Unit Townhome

5 out of 5 average rating, 8 reviews4 days ago

Nicely laid out, huge kitchen & dining space. Read out on the patio, walked up to a hidden pier area and just listened to the water from Goose Creek. Everyone we encountered said hello. Lots of dog walkers. There was a cat that visited the ground level backyard. We weren’t ‘home’ a lot due to a Navy Ceremony, but when we were, it was nice! Huge TV, comfy beds, lots of towels & nice grocery store close by. The only thing worth noting was better TP would be appreciated. But we survived. Great place, highly recommended!

Home in Hanahan

What guests are saying

Mt Pleasant Central location Dog friendly Fenced

4.89 out of 5 average rating, 105 reviews1 month ago

The house was great for our family while we were in town for a wedding! We enjoyed the decor, layout of the home, and the extra pillows and linens. The large living space was great for our family & pups. The location is convenient and close to plenty of shops and restaurants. The road was a little loud at night, but I am a light sleeper and the noise machine did the trick!

Home in Mount Pleasant

What guests are saying

Serene Home in Mount Pleasant Near King Street/Beach/Shops

4.91 out of 5 average rating, 230 reviews2 weeks ago

Neeta's place was great! It was the perfect long weekend stay for my family. It is close to both downtown & the beaches, and it was spacious, clean, and had a big backyard. We also loved the screened in porch! The house doesn't clearly list the street numbers, so it was slightly hard to find in the dark, but I would highly recommend it to anyone looking to stay in Charleston!

Home in Mount Pleasant

1 of 12 pages