
House vacation rentals in Guadalupe
Find and book unique houses on Airbnb
Top-rated house rentals in Guadalupe
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Guadalupe house rentals
House rentals with a pool

Hidden Views

Pool & view in Sta Rita Hills Wine Country, Lompoc

San Luis Obispo House With Pool And Hot Tub

Getaway at the Highlands+Heated Pool+Hot Tub

FairView Lavender Estate

Luxury Mountain View Retreat Pool/jacuzzi

Beautiful ranch style Santa ynez home
Weekly house rentals

Beautiful Country Home

Beach N' Sunsets

Boutique Bungalow, San Luis Obispo

The Beach House - On Cayucos Beach

Wine Country Bungalow 2Bd/1Ba

Beach Home-walk to the Beach STR0116

Shore To Please Beach House Oceano Pismo Avila SLO

Lovely Home w/ HotTub. Up to 6+ months stays ok
Private house rentals

STENNER CREEK RANCH

Upscale. Pet Friendly. Great Location! 2-6 guests

Creative & Colorful Home. Large! Near Pismo! SLO!

The perfect retreat - walk to downtown Santa Ynez!

"Willow" Farmstyle Home in Santa Ynez Township

Heritage House | Los Alamos | Downtown | Eco-friendly

Beautiful Home, Central Coast

Corfu & Ocean View Cottages: Hot tub, 4 King beds
Destinations to explore
- Channel Islands of California Vacation rentals
- San Fernando Valley Vacation rentals
- Santa Monica Vacation rentals
- Central California Vacation rentals
- Los Angeles Vacation rentals
- Stanton Vacation rentals
- Anaheim Vacation rentals
- San Francisco Peninsula Vacation rentals
- San Francisco Bay Area Vacation rentals
- San Francisco Vacation rentals
- Southern California Vacation rentals
- Palm Springs Vacation rentals
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Montaña de Oro State Park
- Dairy Creek Golf Course
- Pismo State Beach
- Arroyo Quemada Beach
- Natalie's Cove
- Gaviota Beach
- Refugio Beach
- Wall Beach
- Pirates Cove Beach
- Allegretto Wines
- Minuteman Beach
- Point Sal State Beach
- Au Bon Climat
- French Camp Vineyards
- Bianchi Winery
- Spooner's Cove
- Coon Creek Beach
- Mission San Luis Obispo de Tolosa
- B & E Vineyard & Winery
- El Capitan Beach
- Seal Beach
- Brown's Beach
- Paradise Beach
- Olde Port Beach
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes