Guesthouse vacation rentals in Greenville

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Popular amenities for Greenville guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
The living area features a comfortable arrangement of seating, including a plush sofa and two armchairs, all positioned around a central coffee table. A colorful area rug adds warmth, while natural light filters through a partially draped window, illuminating the space.
Guesthouse in Travelers Rest
5 out of 5 average rating, 48 reviews

Travelers Rest Country Retreat Two miles to NGU

PeggyRating, 5 stars7 months ago
I can't say anything negative about Cliff and Mary's place. It is a gem. You watch horses graze on one side of the house and overlook a pond on the other side. Cliff and Mary are very responsive and go out of their way anticipating their guests needs, stocking the kitchen and fridge with snacks, coffee, cream, and other goodies. Any questions we had about the area were answered immediately. They are pleasant people that I would be glad to call new friends!
Guest favorite
The exterior of the property is shown, featuring yellow siding complemented by dark shutters on the windows. A single door with glass panels is visible, providing a welcoming entrance. A grassy area is located at the base of the wall, enhancing the outdoor setting.
Guesthouse in Liberty
4.93 out of 5 average rating, 194 reviews

Holly Hideaway! 10 Highway miles to Clemson U!

CliffRating, 5 stars2 months ago
Very informative and mindful host. Will certainly stay again!
Guest favorite
The open living area features a striped armchair facing a wooden coffee table. A kitchen with white cabinetry and a breakfast bar is seen in the background, equipped with modern appliances and natural lighting from multiple windows.
Guesthouse in Simpsonville
4.94 out of 5 average rating, 240 reviews

Private Suite in Downtown Simpsonville

TonyRating, 5 stars1 week ago
I can no longer count how many Airbnbs that I have stayed in. this one is well worth the cost. the location is fantastic if you want to walk to restaurants and/or bars at night. just far enough off the road to have a quiet night sleep. No smells at all inside and very clean. you do have to walk a half flight of stairs to get in but it lands onto a nice patio/porch with seating. I would definitely stay here again.
The kitchen features a functional layout with a white refrigerator and a window providing natural light. A wooden countertop is complemented by bar stools and a small dining area with a decorative fruit bowl and tableware set. Shelves display glasses and a vibrant art piece is visible.
Guesthouse in Greenville
4.78 out of 5 average rating, 46 reviews

Quiet Guest Apartment in the Woods

JenniferRating, 5 stars30 months ago
Miranda's guest apartment was perfect for a long term stay. It was well equipped, neat, and ideally located with easy proximity to Paris Mountain State Park as well as downtown Greenville. Miranda was a wonderful host and prompt to respond the few times I needed something.
Guest favorite
The bathroom features a shower stall with a glass door, accompanied by a compact sink and mirror. A towel rack is mounted on the wall, and shelving holds toiletries. A soft rug is placed in front of the shower, while light grey walls create a calming atmosphere.
Guesthouse in Inman
4.98 out of 5 average rating, 45 reviews

Cozy 1 BR Cottage - Great Location!

Steven LeeRating, 5 stars1 week ago
There are so many things to say about Renee's place. The place was very private,Safe and intimate.The cottage was fully equipped from Kitchen to bathroom to laundry and bedroom.She had every possible thing we needed The location was afew minutes from my son's house and close to grocery stores and restaurants..She had a nice welcome snack assortment which was most welcome after delayed flights and rental car issues..There are sliding doors to most rooms which added to the uniqness and fun atmosphere of the cottage . Definitely had all the comforts of home with a unique and cozy environment..I visit Inman several times a year and hope her spot will be available whenever I come to visit my granddaughter!!!.Steve K
Top guest favorite
The exterior of a barn-style home is framed by vibrant pink azaleas and lush greenery. The building features a sloped roof with a red trim, white siding, and dark shutters. A covered porch area is visible, providing a shaded outdoor space.
Guesthouse in Greer
4.94 out of 5 average rating, 276 reviews

Executive Suite on a farm @GSP Airport

LandonRating, 5 stars1 week ago
Wonderful place! Nice people
Top guest favorite
A spacious private suite features a king bed with soft linens and decorative pillows. The dark accent wall adds depth, while a small kitchenette is visible in the background. Nightstands flank the bed, accompanied by soothing lighting. A plush area rug and bright decor contribute to a welcoming ambiance.
Private room in Pelzer
4.98 out of 5 average rating, 125 reviews

South Oaks Guesthouse

BethRating, 5 stars2 months ago
Diane's place was just what we needed for an overnight stay to watch an early bike race the next morning that took place right near by. The room was clean and the coffee cake was delicious, as described in many other reviews. The room was a bit smaller than expected for the price, but it was beautifully decorated and extremely comfortable. We would definitely stay again!
Guest favorite
Private room in Brevard
4.97 out of 5 average rating, 103 reviews

Studio 84, Brevard NC

JeffRating, 5 stars11 months ago
The pictures are accurate. This place is roomy, in spite of both beds in same room. The neighborhood is quiet and nice. It is just a few blocks from downtown, which is convenient to shops and eateries and great if there is a festival going on. The yard is beautifully landscaped, making this a very pleasant stay. Recommended.

Guest house rentals with a patio

Guest favorite
A charming guest house is depicted with a white exterior and a small balcony. Stairs lead up to the entrance, under a sunset sky painted with hues of orange and purple. The grassy area surrounding the house adds to the serene atmosphere.
Guesthouse in Lyman
4.93 out of 5 average rating, 27 reviews

Budget Bliss: Cozy Elegance

KathyRating, 5 stars5 days ago
Christian’s place was just what we needed, yes it was basic, but that is all we needed for our quick trip to the area. It had a two burner cooktop, microwave, coffee pot and small refrigerator/freezer in the kitchen, small high top table for meals, small shower and a tv, AC, and comfortable queen size bed. And a cute porch which faced a wooded area, that was full of song birds for enjoying morning coffee. We were there basically on business, so we just needed a quiet place to sleep and recoup from the day’s activities. It was clean and comfortable for our short stay. Thanks Christian!
Top guest favorite
Guesthouse in Pelzer
4.97 out of 5 average rating, 36 reviews

Birdsong Bungalow-Family and Pet Friendly

RelissaRating, 5 stars5 days ago
Amy’s place was so welcoming and with a home like feel! She made sure every need was met for our family. We will be making this our yearly spot from now on!
Top guest favorite
A well-appointed sleeping area features a queen bed with a decorative headboard, layered with a soft comforter and throw. Two mirrored bedside tables are positioned beside the bed, each with a lamp. A wall-mounted artwork displays a calming scene, contributing to the inviting atmosphere.
Guesthouse in Columbus
4.99 out of 5 average rating, 76 reviews

Cozy Cottage - 5 miles from TIEC

KeriRating, 5 stars1 week ago
Such a great stay!! The space was laid out so well with so much in it. Bed was so comfy. And had so many special touches. Loved having the back yard space for the dogs and so fun watching Mr. Peacock! Betty and her family were truly a delight and made us feel right at home.
Guest favorite
Guesthouse in Greer
4.96 out of 5 average rating, 46 reviews

Sugar Creek Retreat

RobinRating, 5 stars2 days ago
I’ve stayed in several Airbnb’s and they were nice, but Kristen’s was the best by far. It was the most comfortable place to stay. She gets 2 thumbs up. If I had more thumbs she would get them too. Thank you for accepting us.
Top guest favorite
A living area features a pair of comfortable leather sofas and a coffee table, with a decorative area rug beneath. In the background, a queen bed with a floral-patterned coverlet is positioned beside a wall adorned with artwork depicting guitars.
Guesthouse in Clemson
5 out of 5 average rating, 21 reviews

Adorable Cottage 2 mi. from Death Valley

OrlaRating, 5 stars5 months ago
We had a wonderful stay at Harold and Bonnie’s place. It was a home away from home while we attended a Clemson football game and visited our niece. Everything was spotless, comfortable and welcoming. It was so nice to meet and chat with Harold and Bonnie and we really appreciated the welcome muffins and available snacks that helped us survive our flight home! Would definitely recommend their place to anyone visiting Clemson and have already told our family to book it next time they visit.
Superhost
The exterior of the cozy cottage features a welcoming entry with wooden steps leading to the door. A small table and two chairs are positioned on the porch, while flowering plants are displayed in a window box. Lush trees provide shade in the surrounding area.
Guesthouse in Taylors
4.78 out of 5 average rating, 40 reviews

Botanical Cottage

RenatoRating, 5 stars1 month ago
Mary was such a great host! She was very attentive and made sure we had everything we needed during stay. The space itself was very clean and comfortable and had all the amenities we needed (microwave, fridge, dishes, hot water, TV, extra towels, etc.). The bed was very comfortable to sleep in and the neighborhood was quiet and nice. We would definitely stay here again; thank you Mary!
Top guest favorite
Guesthouse in Greenville
4.94 out of 5 average rating, 36 reviews

Tranquil 2BR Guest House on Pond by Furman

BaoRating, 5 stars2 weeks ago
Pictures don’t do the place justice! The home was so much more beautiful and spacious than we expected!
Top guest favorite
The interior features a cozy living area with a dark gray sectional sofa, complemented by decorative pillows. A circular coffee table sits in front, holding a tray with books and a remote. The kitchen appears in the background, showcasing a modern design with white cabinetry.
Guesthouse in Inman
4.99 out of 5 average rating, 118 reviews

Foothills Favorite

Melanie And JasonRating, 5 stars2 weeks ago
Phyllis's over-garage apartment suite is quiet, well-appointed, comfortable and clean. Phyllis is a wonderful host - kind and proactive. All instructions were clear. The space is modern and spotless - new TV's with guest accounts; rain shower; new appliances; comfortable bed and pillows. Phyllis clearly spared no expense in putting the space together. It is in a somewhat rural area - so private, safe and you can see the stars at night. But, perfectly located to access all things Spartanburg or Greenville in 20-25 minutes. Highly recommend Phyllis's place and will not hesitate to stay there again.

Guest house rentals with a washer and dryer

Guest favorite
The exterior of the guesthouse is showcased, featuring a well-maintained stone patio and decorative landscaping. Large windows allow natural light to fill the space, while a red front door adds a pop of colour. Two inviting chairs with patterned cushions are positioned next to the entrance.
Guesthouse in Greenville
4.98 out of 5 average rating, 99 reviews

The Spring Valley Retreat

LydaRating, 5 stars3 weeks ago
We had a wonderful stay here . We felt like we were at a true bed and breakfast .we brought our kids and they provided us with a few indoor toys that the boys loved and bubbles for the outside patio that they played with every morning while I had a cup of coffee. The hosts and the location were fantastic 10 min or less to everything we needed .
Superhost
A modern living area features a sleek black sectional sofa with orange accent pillows. Large windows provide natural light and views of the patio. A wall-mounted TV and two armchairs complement the spacious, airy environment.
Guesthouse in Travelers Rest
4.78 out of 5 average rating, 18 reviews

Quiet King Two Bedrm House

CherieRating, 5 stars1 month ago
It was a nice space for a weekend at Furman. Close to downtown Travelers Rest. They have done a nice job renovated an older home. They were quick to answer any question. We had all our needs met. The backyard has a lot more potential, but it also looks like they have to clear some damage from the hurricane.
Guest favorite
The private deck features wooden flooring and is furnished with two wicker chairs and a small table. A ceiling fan is mounted above, providing a cooling breeze. Large sliding glass doors showcase the indoor space while offering a view of the surrounding greenery.
Guesthouse in Greenville
4.89 out of 5 average rating, 66 reviews

Chic Studio with Private Deck

RosalindRating, 5 stars2 weeks ago
Very comfortable and well equipped space. I especially liked having the back porch. Host was very responsive. Definitely would stay here again.
Top guest favorite
Two lightweight chairs with soft, upholstered seats are positioned on a brick patio. A white fence stands in the background, while mature trees and lush greenery create a serene outdoor space. A decorative planter is visible beside the chairs, adding to the inviting atmosphere.
Guesthouse in Brevard
4.97 out of 5 average rating, 34 reviews

The Cottage off Main - 1 bedroom

JaniceRating, 5 stars3 months ago
The location near the center of town requires only a short walk to shops and excellent restaurants. During our (winter) visit things were very quiet. Everything was clean and in top condition. This is a stellar property and we would happily stay there again.
Top guest favorite
A bathroom is depicted featuring a sleek vanity with a granite countertop and a circular mirror illuminated by overhead lights. Soft towels are neatly arranged on shelves beside a curtain that partially separates the shower area. A decorative rug enhances the space.
Guesthouse in Easley
5 out of 5 average rating, 45 reviews

Fun, cozy cottage for two w/games, deck in Easley

BrianaRating, 5 starstoday
we found shannon’s place very last minute when my husband had to rush down here to be at his terminally ill mothers side. shannon was sweet, caring, and her home gave my husband comfort when he would come back from the hospital after a very long day. if we have to come back to the area, this is our new spot
Guest favorite
A modern kitchen is presented, featuring white cabinetry and a wood countertop. A black stove and microwave stand against the wall, with a sink positioned nearby. Natural light filters through the window, highlighting decorative elements on the shelves.
Guesthouse in Clemson
4.94 out of 5 average rating, 17 reviews

Clemson Carriage House - NEW!

KathrynRating, 5 stars1 month ago
We loved this adorable apartment! Everything was so clean and nice and we loved all the Clemson tigers everywhere! Would definitely come back for another stay!
Top guest favorite
A modern kitchen is highlighted by sleek white cabinetry and stainless steel appliances. A wood-topped island with four pink bar stools creates a functional dining space. Soft lighting enhances the clean lines and minimalist décor, inviting comfort and convenience.
Guesthouse in Duncan
5 out of 5 average rating, 62 reviews

Adorable renovated private house w/ parking.

LisaRating, 5 stars1 month ago
Great place to stay!
Top guest favorite
A serene lakefront view showcases a calm body of water and a private dock. Lush greenery lines the shores, while colorful kayaks are visible near the dock. A spacious patio area with seating and a fire pit is also present, inviting outdoor relaxation.
Guesthouse in Lyman
4.99 out of 5 average rating, 145 reviews

Blue Heron Hideaway Lakeside Retreat

KatRating, 5 stars5 months ago
Beautiful and serene place! We felt right at home-relaxing and peaceful! Patricia and Bill are gracious and accomodating hosts. We’ll be back for sure when in this area!

Quick stats about guesthouse rentals in Greenville

  • Total rentals

    30 properties

  • Nightly prices starting at

    $60 before taxes and fees

  • Total number of reviews

    3K reviews

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wifi availability

    30 properties include access to wifi

  • Popular amenities

    Kitchen, Wifi, and Pool

Destinations to explore