
Guesthouse vacation rentals in Greenville
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Top-rated guesthouse rentals in Greenville
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Greenville guesthouse rentals
Family-friendly guest house rentals

Travelers Rest Country Retreat Two miles to NGU
I can't say anything negative about Cliff and Mary's place. It is a gem. You watch horses graze on one side of the house and overlook a pond on the other side. Cliff and Mary are very responsive and go out of their way anticipating their guests needs, stocking the kitchen and fridge with snacks, coffee, cream, and other goodies. Any questions we had about the area were answered immediately. They are pleasant people that I would be glad to call new friends!

Holly Hideaway! 10 Highway miles to Clemson U!
Very informative and mindful host. Will certainly stay again!

Private Suite in Downtown Simpsonville
I can no longer count how many Airbnbs that I have stayed in. this one is well worth the cost. the location is fantastic if you want to walk to restaurants and/or bars at night. just far enough off the road to have a quiet night sleep. No smells at all inside and very clean. you do have to walk a half flight of stairs to get in but it lands onto a nice patio/porch with seating. I would definitely stay here again.

Quiet Guest Apartment in the Woods
Miranda's guest apartment was perfect for a long term stay. It was well equipped, neat, and ideally located with easy proximity to Paris Mountain State Park as well as downtown Greenville. Miranda was a wonderful host and prompt to respond the few times I needed something.

Cozy 1 BR Cottage - Great Location!
There are so many things to say about Renee's place. The place was very private,Safe and intimate.The cottage was fully equipped from Kitchen to bathroom to laundry and bedroom.She had every possible thing we needed The location was afew minutes from my son's house and close to grocery stores and restaurants..She had a nice welcome snack assortment which was most welcome after delayed flights and rental car issues..There are sliding doors to most rooms which added to the uniqness and fun atmosphere of the cottage . Definitely had all the comforts of home with a unique and cozy environment..I visit Inman several times a year and hope her spot will be available whenever I come to visit my granddaughter!!!.Steve K

Executive Suite on a farm @GSP Airport
Wonderful place! Nice people

South Oaks Guesthouse
Diane's place was just what we needed for an overnight stay to watch an early bike race the next morning that took place right near by. The room was clean and the coffee cake was delicious, as described in many other reviews. The room was a bit smaller than expected for the price, but it was beautifully decorated and extremely comfortable. We would definitely stay again!

Studio 84, Brevard NC
The pictures are accurate. This place is roomy, in spite of both beds in same room. The neighborhood is quiet and nice. It is just a few blocks from downtown, which is convenient to shops and eateries and great if there is a festival going on. The yard is beautifully landscaped, making this a very pleasant stay. Recommended.
Guest house rentals with a patio

Budget Bliss: Cozy Elegance
Christian’s place was just what we needed, yes it was basic, but that is all we needed for our quick trip to the area. It had a two burner cooktop, microwave, coffee pot and small refrigerator/freezer in the kitchen, small high top table for meals, small shower and a tv, AC, and comfortable queen size bed. And a cute porch which faced a wooded area, that was full of song birds for enjoying morning coffee. We were there basically on business, so we just needed a quiet place to sleep and recoup from the day’s activities. It was clean and comfortable for our short stay. Thanks Christian!

Birdsong Bungalow-Family and Pet Friendly
Amy’s place was so welcoming and with a home like feel! She made sure every need was met for our family. We will be making this our yearly spot from now on!

Cozy Cottage - 5 miles from TIEC
Such a great stay!! The space was laid out so well with so much in it. Bed was so comfy. And had so many special touches. Loved having the back yard space for the dogs and so fun watching Mr. Peacock! Betty and her family were truly a delight and made us feel right at home.

Sugar Creek Retreat
I’ve stayed in several Airbnb’s and they were nice, but Kristen’s was the best by far. It was the most comfortable place to stay. She gets 2 thumbs up. If I had more thumbs she would get them too. Thank you for accepting us.

Adorable Cottage 2 mi. from Death Valley
We had a wonderful stay at Harold and Bonnie’s place. It was a home away from home while we attended a Clemson football game and visited our niece. Everything was spotless, comfortable and welcoming. It was so nice to meet and chat with Harold and Bonnie and we really appreciated the welcome muffins and available snacks that helped us survive our flight home! Would definitely recommend their place to anyone visiting Clemson and have already told our family to book it next time they visit.

Botanical Cottage
Mary was such a great host! She was very attentive and made sure we had everything we needed during stay. The space itself was very clean and comfortable and had all the amenities we needed (microwave, fridge, dishes, hot water, TV, extra towels, etc.). The bed was very comfortable to sleep in and the neighborhood was quiet and nice. We would definitely stay here again; thank you Mary!

Tranquil 2BR Guest House on Pond by Furman
Pictures don’t do the place justice! The home was so much more beautiful and spacious than we expected!

Foothills Favorite
Phyllis's over-garage apartment suite is quiet, well-appointed, comfortable and clean. Phyllis is a wonderful host - kind and proactive. All instructions were clear. The space is modern and spotless - new TV's with guest accounts; rain shower; new appliances; comfortable bed and pillows. Phyllis clearly spared no expense in putting the space together. It is in a somewhat rural area - so private, safe and you can see the stars at night. But, perfectly located to access all things Spartanburg or Greenville in 20-25 minutes. Highly recommend Phyllis's place and will not hesitate to stay there again.
Guest house rentals with a washer and dryer

The Spring Valley Retreat
We had a wonderful stay here . We felt like we were at a true bed and breakfast .we brought our kids and they provided us with a few indoor toys that the boys loved and bubbles for the outside patio that they played with every morning while I had a cup of coffee. The hosts and the location were fantastic 10 min or less to everything we needed .

Quiet King Two Bedrm House
It was a nice space for a weekend at Furman. Close to downtown Travelers Rest. They have done a nice job renovated an older home. They were quick to answer any question. We had all our needs met. The backyard has a lot more potential, but it also looks like they have to clear some damage from the hurricane.

Chic Studio with Private Deck
Very comfortable and well equipped space. I especially liked having the back porch. Host was very responsive. Definitely would stay here again.

The Cottage off Main - 1 bedroom
The location near the center of town requires only a short walk to shops and excellent restaurants. During our (winter) visit things were very quiet. Everything was clean and in top condition. This is a stellar property and we would happily stay there again.

Fun, cozy cottage for two w/games, deck in Easley
we found shannon’s place very last minute when my husband had to rush down here to be at his terminally ill mothers side. shannon was sweet, caring, and her home gave my husband comfort when he would come back from the hospital after a very long day. if we have to come back to the area, this is our new spot

Clemson Carriage House - NEW!
We loved this adorable apartment! Everything was so clean and nice and we loved all the Clemson tigers everywhere! Would definitely come back for another stay!

Adorable renovated private house w/ parking.
Great place to stay!

Blue Heron Hideaway Lakeside Retreat
Beautiful and serene place! We felt right at home-relaxing and peaceful! Patricia and Bill are gracious and accomodating hosts. We’ll be back for sure when in this area!
Quick stats about guesthouse rentals in Greenville
Total rentals
30 properties
Nightly prices starting at
$60 before taxes and fees
Total number of reviews
3K reviews
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Wifi availability
30 properties include access to wifi
Popular amenities
Kitchen, Wifi, and Pool
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- Blue Ridge Parkway
- Lake Lure Beach and Water Park
- Table Rock State Park
- Gorges State Park
- Ski Sapphire Valley
- Jump Off Rock
- Mountaintop Golf & Lake Club
- Tugaloo State Park
- The North Carolina Arboretum
- Old Edwards Club
- Vineyards for Biltmore Winery
- Discovery Island
- Chimney Rock State Park
- Wade Hampton Golf Club
- Victoria Valley Vineyards
- Biltmore Forest County Club
- Carl Sandburg Home National Historic Site
- Haas Family Golf
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