Guesthouse vacation rentals in Greenville County

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Popular amenities for Greenville County guesthouse rentals

Family-friendly guest house rentals

Guest favorite

Guesthouse in Travelers Rest

5 out of 5 average rating, 48 reviews

Travelers Rest Country Retreat Two miles to NGU

PeggyRating, 5 stars3 months ago
I can't say anything negative about Cliff and Mary's place. It is a gem. You watch horses graze on one side of the house and overlook a pond on the other side. Cliff and Mary are very responsive and go out of their way anticipating their guests needs, stocking the kitchen and fridge with snacks, coffee, cream, and other goodies. Any questions we had about the area were answered immediately. They are pleasant people that I would be glad to call new friends!
Guest favorite

Guesthouse in Tryon

4.98 out of 5 average rating, 108 reviews

Historic Jockey Cottage, TIEC 20 mins, Tryon 5

TracyRating, 5 stars1 month ago
We absolutely loved the jockey house!!! Terry and Bill greeted us and were available if needed. The house was well appointed with anything you may need, comfy beds and best airbnb coffee bar!! Location is also fantastic- short drive to Tryon, Landrum and Asheville- so much to see and do.
Guest favorite

Guesthouse in Liberty

4.93 out of 5 average rating, 190 reviews

Holly Hideaway! 10 Highway miles to Clemson U!

LarisaRating, 5 stars3 weeks ago
When I asked if there was a chair to sit outside and drink my coffee, she set me up with a patio chair, foot stool and side table where I got the morning sun and could look out at the golden trees. That is a sweet host! The hollies that screened the studio from the main house were full of berries. Close to everything I needed to get to.
Superhost

Guesthouse in Pendleton

4.89 out of 5 average rating, 252 reviews

La Bella Farm

JessicaRating, 5 stars2 weeks ago
This place was exactly what we needed! We had a group of four come down for a Clemson game. We brought an air mattress but the place was plenty big for the four of us. The kitchen was stocked and the place was clean. The hosts were very friendly and prompt with any questions. Would definitely stay here again!
Guest favorite

Guesthouse in Simpsonville

4.94 out of 5 average rating, 232 reviews

Private Suite in Downtown Simpsonville

MarissaRating, 5 stars2 months ago
We had a great stay at Shari’s place! The location to the downtown Main Street of Simpsonville was unbeatable. Shari was very helpful and responsive and I would definitely stay here again!

Guesthouse in Greenville

4.78 out of 5 average rating, 46 reviews

Quiet Guest Apartment in the Woods

JenniferRating, 5 stars26 months ago
Miranda's guest apartment was perfect for a long term stay. It was well equipped, neat, and ideally located with easy proximity to Paris Mountain State Park as well as downtown Greenville. Miranda was a wonderful host and prompt to respond the few times I needed something.
Guest favorite

Guesthouse in Greer

4.94 out of 5 average rating, 265 reviews

Executive Suite on a farm @GSP Airport

SarahRating, 5 stars3 weeks ago
I can't say enough about this place. My husband & I agreed it's one of the nicest - if not THE nicest - Airbnb we've ever stayed at. The location is great, mins from restaurants etc but feeling like out in the country. The grounds are lovely, with a tree lined driveway and a garden. The place itself...everywhere you look is something interesting, art & books etc. The bed was super comfortable. It was nice having a full kitchen, & the table for two overlooking the garden made for a lovely b'fast. We ended up staying in rather than going out for the day because we wanted to enjoy the Airbnb! We watched movies, worked on a puzzle, took a walk, drank coffee then wine, just relaxed. I was only sad that we weren't staying longer! What an experience. Not sure our travels will bring us to Greer again but 100% would love to stay here again.
Guest favorite

Private room in Pelzer

4.98 out of 5 average rating, 124 reviews

South Oaks Guesthouse

JessicaRating, 5 stars1 month ago
I love staying here. My second visit went just as well as the first. Feels like home. Great shower and comfortable bed. always love the cake and flowers. Peaceful and I love that there is no TV. Very relaxed setting can come and go with freedom and ease.

Guest house rentals with a patio

Guest favorite

Guesthouse in Lyman

4.9 out of 5 average rating, 21 reviews

Budget Bliss: Cozy Elegance

ValeriaRating, 5 stars2 months ago
This property was very nice & clean. The location and ambiance was beautiful.
Guest favorite

Guesthouse in Greenville

4.88 out of 5 average rating, 60 reviews

Chic Studio with Private Deck

TomRating, 5 stars3 weeks ago
Super clean, with a balcony and laundry. Bathroom has everything you need. Big TV, and comfy bed. Is exactly like the pix.
Guest favorite

Guesthouse in Pelzer

5 out of 5 average rating, 24 reviews

Birdsong Bungalow-Bring the kids and the dog

JaylaRating, 5 stars1 week ago
Amy thought of absolutely everything, this was the perfect little get away for my family, my babies enjoyed the toys,Christmas tree,hot chocolate, and Christmas movies on tv and I enjoyed being able to kick back and relax. I loved that there was a a washing machine and laundry detergent available along with all the basic necessities, can’t wait to come back 🙂
Guest favorite

Guesthouse in Greer

4.94 out of 5 average rating, 35 reviews

Sugar Creek Retreat

StephanieRating, 5 stars3 weeks ago
Everything was perfect for our short stay. My daughter commented she could live there. It was cozy and had everything we needed. Would recommend and would definitely stay again.
Guest favorite

Guesthouse in Taylors

4.88 out of 5 average rating, 33 reviews

Botanical cottage

Cassie Rating, 5 stars1 month ago
My husband and I were in town for a work trip and decided last minute that we wanted to stay at an AirBnB for the night. Mary was responsive and very kind! Check in was super easy. The home was clean and quiet. The bed was super comfy as well. 4-5 minutes to most restaurants in town. Would stay again!!
Guest favorite

Guesthouse in Greenville

4.94 out of 5 average rating, 31 reviews

Tranquil 2BR Guest House on Pond by Furman

ThomasRating, 5 stars1 month ago
This was my second stay at Gabriella 's rental. The location is perfect for me as it is close to everything I enjoy doing in Greenville. Not far from downtown yet the neighborhood is very quiet. Also close to Traveler's Rest, Furman and the golf courses we enjoy playing.
Guest favorite

Guesthouse in Piedmont

4.99 out of 5 average rating, 72 reviews

Shou-Sugi-Ban Retreat on the Saluda River

CrystalRating, 5 stars1 week ago
Emma was awesome she was very responsive and help me with getting an extra heater. We are greatful for finding this gem. I would love to stay her again. Thank you
Guest favorite

Guesthouse in Greenville

5 out of 5 average rating, 10 reviews

Sweet Sans Souci Studio

JonathanRating, 5 stars3 months ago
This was such a peaceful, quiet, calm, and fantastic month-long stay. I loved the feel of the space and felt right at home. Laura and Johnathan are both very nice and have worked hard to implement thoughtful touches and modern decor. Laura is incredibly responsive, thoughtful, helpful, and an excellent conversationalist. She went above and beyond to make sure everything went well. The bed is big and comfortable, lots of space in the shower, strong internet, a nice TV, a garage for parking, you're not far from downtown, cute neighborhood businesses, walkable trails, a bike on offer, really good AC, all the utensils you might need, and much more. There isn't enough room to write everything about this wonderful place and these fantastic hosts! I would rent this for the long haul if I could! An excellent place!

Guest house rentals with a washer and dryer

Guest favorite

Guesthouse in Greenville

4.99 out of 5 average rating, 91 reviews

The Spring Valley Retreat

RichRating, 5 stars3 weeks ago
Beautifully decorated and very cozy & comfortable. Great neighborhood. Recommended!
Guest favorite

Guesthouse in Fountain Inn

4.98 out of 5 average rating, 87 reviews

Upscale cottage in Downtown Fountain Inn

JeremyRating, 5 stars4 weeks ago
I really enjoyed the place for my work week in town. It was perfect for me to relax after work and very clean! Great host too!
Superhost

Guesthouse in Travelers Rest

4.85 out of 5 average rating, 13 reviews

Quiet King Two Bedrm House

StephanieRating, 5 stars3 weeks ago
John and Breanna went above and beyond to make sure my family was comfortable. A tree fell on our home during Hurricane Helene and John and Breanna made sure we felt at home.
Superhost

Guesthouse in Greenville

4.79 out of 5 average rating, 63 reviews

TheArk

MichelleRating, 5 stars2 months ago
David was very accommodating on a last minute basis. Very nice place to stay while visiting the area.
Superhost

Guesthouse in Greenville

4.97 out of 5 average rating, 36 reviews

Mod studio- loft, outdoor covered space & parking

GigiRating, 5 stars2 months ago
The airbnb was just as described if not cuter! The patio was a great space as well to hangout.
Guest favorite

Guesthouse in Duncan

5 out of 5 average rating, 56 reviews

Adorable renovated private house w/ parking.

LatrishaRating, 5 stars3 weeks ago
We greatly enjoyed our stay. Very convenient location off the highway and right in the middle of Greenville, Greer, and Spartanburg. Place is just as described and was actually much bigger than expected. Excellent value for the place. Check in was smooth and easy. I would not hesitate to rent again.
Guest favorite

Guesthouse in Pelzer

4.96 out of 5 average rating, 50 reviews

Quaint guest cottage in Upstate

David Rating, 5 stars1 week ago
Felt right at home as soon as we walked in! Very tastefully decorated - would definitely recommend and would stay again!
Guest favorite

Guesthouse in Greenville

4.95 out of 5 average rating, 37 reviews

Nishleigh's Nook - West End Downtown Greenville

MimiRating, 5 stars1 week ago
Such a lovely place! A little odd getting there, but so thoughtfully appointed inside. Nicholas was very responsive and helpful. You need to be able to climb the rather steep stairs to get to the space, which was fine for us. We heard the nearby train before sundown and in the morning, but NOT at night or while sleeping. Very comfy couch, bed, and pillows, and a beautifully designed place.

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