House vacation rentals in Florence
Find and book unique houses on Airbnb
Top-rated house rentals in Florence
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Florence house rentals
House rentals with a pool
Home in Columbia
4.9 out of 5 average rating, 131 reviewsSouthern Comfort 4bed- saltwater pool- Ft. Jackson
Home in Myrtle Beach
4.9 out of 5 average rating, 359 reviewsBeach Style Cottage One Block To Beach!
Home in North Myrtle Beach
4.93 out of 5 average rating, 161 reviewsLuxury Villa in Caribbean-Style Beach Resort
Home in Summerton
4.97 out of 5 average rating, 115 reviewsLuxurious Lakefront Log Home W/Pool & hot tub
Home in North Myrtle Beach
4.99 out of 5 average rating, 103 reviewsLuxury Ocean View - Private Pool/Jacuzzi, Elevator
Home in Charlotte
4.82 out of 5 average rating, 139 reviewsClose Yet Private: Epic Location, Pool & Hot Tub!
Home in Myrtle Beach
4.91 out of 5 average rating, 192 reviewsPrivate Beach Paradise in Ocean Lakes w/ Golf Cart
Home in Myrtle Beach
4.8 out of 5 average rating, 209 reviewsComfortable 2-BR Cottage, 2 Blocks To Beach
Weekly house rentals
Home in Georgetown
4.98 out of 5 average rating, 115 reviews"Almost There" ~ Georgetown SC
Home in Georgetown
4.99 out of 5 average rating, 120 reviewsBlack River Refuge on the Water
Home in Sumter
4.85 out of 5 average rating, 124 reviewsCozy, Quiet Cottage With Wood-Burning Fire-Pit
Home in Myrtle Beach
4.97 out of 5 average rating, 104 reviewsCoastal Get Away
Home in Fayetteville
4.91 out of 5 average rating, 597 reviewsRenovated Haymount Home.Less than 10 min from I-95
Home in Hope Mills
4.84 out of 5 average rating, 682 reviewsClosest BnB to I-95! Kid-happy home away from home
Home in Fayetteville
4.98 out of 5 average rating, 274 reviewsHistoric Haymount Modern Farmhouse
Home in Pinebluff
4.99 out of 5 average rating, 106 reviewsHot Tub * King Bed * Putting Green * Amazing Golf
Private house rentals
Home in Florence
4.88 out of 5 average rating, 8 reviews2b/1.5bath brand NEW townhouse Closed to MUSC
Home in Bishopville
4.95 out of 5 average rating, 40 reviewsThe Blue Door House
Home in Florence
4.92 out of 5 average rating, 13 reviewsCan do condo!
Home in Florence
5.0 out of 5 average rating, 27 reviewsCozy and comfortable
Home in Sumter
5.0 out of 5 average rating, 9 reviewsComfy Stay at “Holiday House”
Home in Florence
4.8 out of 5 average rating, 40 reviewsCozy 3 Bedroom Home! Located NEAR MUSC-Florence
Home in Florence
4.98 out of 5 average rating, 44 reviewsCozy home in Florence, SC
Home in Dalzell
4.98 out of 5 average rating, 86 reviewsHome away from home
Quick stats about house rentals in Florence
Total rentals
60 properties
Rentals with dedicated workspaces
40 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
1.3K reviews
Nightly prices starting at
$10 before taxes and fees
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- Family travel hub Tips and inspiration
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