Lake house vacation rentals in South Carolina
Find and book unique lake houses on Airbnb
Top-rated lake house rentals in South Carolina
Guests agree: these lake houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for South Carolina lake house rentals
Waterfront lakehouse rentals
Home in Chappells
4.95 out of 5 average rating, 145 reviewsGreenwood Lake Front, FirePit, Outside Kitch, Dock
Jan 28 – Feb 4
Home in Inman
4.95 out of 5 average rating, 103 reviewsMaggie's Lake House
Oct 12 – 19
Home in Inman
4.93 out of 5 average rating, 230 reviewsLakingitEz..3BR/2BA amazing sunsets & hot tub
Dec 15 – 22
Home in Ridgeway
4.96 out of 5 average rating, 111 reviews3000 sq ft lake house with views from every window
Oct 27 – Nov 3
Home in Inman
4.99 out of 5 average rating, 149 reviewsLAKE LIFE...
Mar 30 – Apr 6
Home in Chapin
4.9 out of 5 average rating, 104 reviewsLake Murray Family Retreat | BIG Water View Chapin
Dec 16 – 23
Home in Myrtle Beach
4.91 out of 5 average rating, 190 reviewsPrivate Beach Paradise in Ocean Lakes w/ Golf Cart
Dec 29 – Jan 5
Home in Fair Play
4.96 out of 5 average rating, 48 reviewsWaterfall Cove - East
Jul 19 – 26
Pet-friendly lake house rentals
Home in Bluffton
4.98 out of 5 average rating, 123 reviewsOld Town Bluffton Cottage - Includes Golf Cart!
Feb 4 – 11
Home in Inman
4.95 out of 5 average rating, 102 reviewsCasa del Lago...Come Relax...You are on Lake Time!
Feb 27 – Mar 6
Home in Modoc
4.93 out of 5 average rating, 104 reviewsIvy’s Escape (water front) at Lake Thurmond
Jul 29 – Aug 5
Home in Easley
4.92 out of 5 average rating, 133 reviewsLarge lake house - 15 min to Downtown Greenville
Apr 8 – 15
Home in Anderson
4.99 out of 5 average rating, 138 reviewsLake House, close to Clemson Kayaks & Paddleboards
Jul 7 – 14
Home in Hilton Head Island
4.92 out of 5 average rating, 106 reviewsLuxe & Fun Family Gem ~ Walk to Beach ~ Pool ~ BBQ
Feb 11 – 18
Home in Lexington
4.87 out of 5 average rating, 143 reviewsLake Murray Paradise~2 BR, 1 Bth, Kit/Living area.
Oct 13 – 20
Home in Seneca
4.85 out of 5 average rating, 174 reviewsCozy Lake House 5 miles from Clemson w Dock
Dec 13 – 20
Private lake house rentals
Home in Ridgeville
4.82 out of 5 average rating, 191 reviewsFarm House Lodge at Natural Gathering Grounds
Aug 7 – 14
Home in Gilbert
4.96 out of 5 average rating, 134 reviews10 Mile View on Lake Murray w/ Dock and Ramp
Oct 13 – 20
Home in Tamassee
5.0 out of 5 average rating, 24 reviewsWhitewater Lake Front Cottage
Dec 30 – Jan 6
Home in Cross Hill
5.0 out of 5 average rating, 4 reviewsLakeside Paradise!
Aug 23 – 30
Home in Summerton
5.0 out of 5 average rating, 81 reviewsCheerful 3 bedroom home on the lake
Dec 31 – Jan 7
Home in Ninety Six
5.0 out of 5 average rating, 25 reviewsLakefront Retreat
Dec 12 – 19
Home in Branchville
4.93 out of 5 average rating, 30 reviewsEdisto River Turnhole Getaway
Aug 5 – 10
Home in Anderson
4.99 out of 5 average rating, 68 reviewsLakefront dock *Hot tub* Anderson Clemson King bed
Jul 11 – 18
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