
House vacation rentals in Tupelo
Find and book unique houses on Airbnb
Top-rated house rentals in Tupelo
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Tupelo house rentals
House rentals with a pool

Thaxton Meadows
We enjoyed our stay at Barry's house. The house was beautiful and peaceful. Far enough from Oxford to get out of the hustle of town but close enough to feel like you could enjoy all that Oxford offers. We also loved the pool table upstairs and had many nights playing to wind down after a busy day. We would definitely stay at Barry's home again in a heartbeat.

House on the hill
We had a wonderful Thanksgiving stay at Amy’s house. It was extremely clean and welcoming! She had everything we could ever need and beautiful farm views. Thanks for everything and we will definitely be back.

Tupelo Manor 6 bed/ 5 bath
Had a fantastic stay! Everything was perfect from start to finish. Place was exactly as described, felt right at home and would absolutely stay here again. Highly recommend.

An outdoor paradise
Ivan was very helpful along the way and gave great instructions. The house was just as it looked in pictures and the backyard was beautiful. It was perfect for a game day weekend with family and friends!
Weekly house rentals

Beautiful 3BR2B(Entire Home) 30 mins Oxford, MS
This is a lovely home in a great spot if you are visiting Pontotoc—especially if you are there to bike the trail. The beds and furniture are comfortable, the kitchen is well stocked, and the surrounding are just beautiful and peaceful. Great value for a great home!

Shady Acres Retreat near Elvis Presley birthplace.
As usual my group thoroughly enjoyed staying here. It was convenient to where we were working. We never have to worry about the cleanliness. I think this may have been our fourth time staying here and look forward to next time.

Charming Family Bungalow
Great host , quick response time and always had an answer . Made my stay in the area very comfortable and stress free ! Wish more places were like hers

TallahatchieTownhouse | Downtown ON the Tanglefoot
The price was great, the place was comfortable and inviting. The TV’s are logged in to multiple streaming apps for easy watching, the bedrooms are spacious and cozy and the host was great and quickly responds!

Tranquil True JOI
Overall it is a great place to stay! Odessa has several cottages all together and would be great for families looking to stay close together. There is a park and walking trail right across the street! I did have to clean some of the dishes before use and there are a few additional rules not posted on the listing. If we come back to town, I would book here again!

West Tupelo Retreat
We enjoyed our time in this great home! Very clean, spacious, and well stocked. It met our needs perfectly and we would definitely stay here again if we are in the area!

Remodeled Historical Home
This was a great house for our group. Plenty of room for everyone to sleep. The kitchen was spacious for cooking meals. The living areas offered plenty of room for everyone

May I Have Your Attention please
Amy’s home is beautiful inside and out. It was the perfect spot for a quick getaway. The home is stocked with everything you need to feel at home. The views outside were amazing and so cozy.
Private house rentals

Wiygul Manor
When I had questions, he responded quickly. Very beautiful place, very quiet and clean. Our dogs felt right at home.

Oleput Overnight
Booked for a convention in town and it was exactly what I needed! The hosts were very responsive and friendly. If you’re in Tupelo and need a place to stay, reserve your nights here!

Fab 3 Bdrm/3 Bed/2 Ba Home, in the Heart of Tupelo
My wife and I along with another couple stayed at Mimi’s Place for the New Year’s Holiday. From the beginning, the host, Leslie, was extremely helpful and responsive, answering our questions and giving information. Leslie sent us the door code the morning of our stay and self-check-in was a breeze. We got there, the home was better than advertised; such a warm, homey feel and beautifully decorated. She left us a handwritten note, the home’s Welcome Guide, crisp apples and even made sure the ice and water in the Brita were fresh. All the amenities were as described, some even better. Leslie contacted us after her last guest had reported an issue with the home’s water pressure to let us know that she was having it addressed as quickly as possible. Once we got there, we had absolutely no issues. I give Leslie Mart and Mimi’s Place an all-around 5-STAR PLUS. I couldn’t have asked for anything more. Great home, Great host, Great value. I will certainly stay here again.

Heart Break Hotel Rad Bungalow
My stay was wonderful, the home was unique and so cuteee (huge fan of black and pink). I’ve never been to Mississippi and I felt safe and comfortable. It was a chilly weekend, but the shower stayed nice and hot and the heat was great, especially considering it’s a older home. I’d definitely stay again. Thank you 🖤 🤘🏽 🎸
Quick stats about house rentals in Tupelo
Total rentals
60 properties
Total number of reviews
3.2K reviews
Family-friendly rentals
40 properties are a good fit for families
Pet-friendly rentals
30 properties allow pets
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wifi availability
60 properties include access to wifi
Destinations to explore
- Memphis Vacation rentals
- Oxford Vacation rentals
- Tuscaloosa Vacation rentals
- Starkville Vacation rentals
- Sardis Lake Vacation rentals
- Lewis Smith Lake Vacation rentals
- Wheeler Lake Vacation rentals
- Jackson Vacation rentals
- Florida Panhandle Vacation rentals
- Destin Vacation rentals
- Atlanta Vacation rentals
- Nashville Vacation rentals
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes