Hotel vacation rentals in Santa Cruz Island
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Top-rated hotel rentals in Santa Cruz Island
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Cruz Island hotel rentals
Family-friendly hotel rentals
Hotel in Puerto Ayora
4.58 out of 5 average rating, 19 reviewsHostal Costa del Pacifico - Twin Room
Hotel room in Puerto Ayora
4.74 out of 5 average rating, 31 reviewsGalapagos Dreams Double
Hotel room in Puerto Ayora
4.75 out of 5 average rating, 85 reviewsNelyza's Suites & Adventure
Boutique hotel in El Garrapatero
4.6 out of 5 average rating, 10 reviewsEnchanted Lodge
Hostel in Puerto Ayora
4.93 out of 5 average rating, 15 reviewsKING OR TWIN BEDS SUITE WITH BALCONY ON 2ND FLOOR
Hotel in Galapagos/Santa Cruz/Puerto Ayora
4.59 out of 5 average rating, 39 reviewsGloria-Galapagos Inn_Triple
Hotel in Puerto Ayora
4.54 out of 5 average rating, 13 reviewsFamily Twin Room
Hostel in Puerto Ayora
4.36 out of 5 average rating, 11 reviewsHOSTAL CASACASCADA Double Room
Hotel rentals with a pool
Hotel in Puerto Ayora
Natura Gardens Galapagos hotel
Hotel in Santa Cruz
Hotel Tortuga Bay EC
Hotel room in Puerto Ayora
4.75 out of 5 average rating, 16 reviewsHOTEL COLOMA GALAPAGOS : DOUBLE ROOM
Hotel room in Puerto Ayora
HOTEL COLOMA GALAPAGOS: TWIN ROOM
Hotel room in Puerto Ayora
HOTEL COLOMA GALAPAGOS TWIN ROOM
Hotel room in Puerto Ayora
HOTEL COLOMA GALAPAGOS - FAMILY ROOM
Hotel in Puerto Ayora
4.64 out of 5 average rating, 14 reviewsBudget and Cozy Double Room
Hotel in Puerto Ayora
4.5 out of 5 average rating, 4 reviewsCute Triple Room with TV and Pool
Hotel rentals with a patio
Room in Puerto Ayora
4.63 out of 5 average rating, 24 reviewsGALAPAGOS DOVE #5
Hotel in Puerto Ayora
4.61 out of 5 average rating, 18 reviewsBeautiful oceanfront double room.
Nature lodge in Santa Cruz
Cabañas El Eden
Hotel in Puerto Ayora
New place to stayYour best adventure starts here Triple
Hotel in Puerto Ayora
New place to stayStandard Room at Hotel Santa Fe
Hotel in Puerto Ayora
Albatros / Deluxe Double Room
Boutique hotel in Puerto Ayora
Spacious & Comfotable Twin Room with Pool
Hotel in Puerto Ayora
Suite matrimonial
Destinations to explore
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- Hotel rentals Galápagos Islands
- Boutique hotel rentals Galápagos Islands
- Kid-friendly rentals Santa Cruz Island
- Rentals with a patio Santa Cruz Island
- Pet-friendly rentals Santa Cruz Island
- Serviced apartment rentals Santa Cruz Island
- Smoking-friendly rentals Santa Cruz Island
- Monthly Rentals Santa Cruz Island
- Rentals with a hot tub Santa Cruz Island
- Rentals with outdoor seating Santa Cruz Island
- Bed and breakfasts Santa Cruz Island
- Rentals with a washer and dryer Santa Cruz Island
- Rentals with breakfast Santa Cruz Island
- Rentals with beach access Santa Cruz Island
- Waterfront rentals Santa Cruz Island
- Rentals with pools Santa Cruz Island
- Rentals with a fire pit Santa Cruz Island
- Apartment rentals Santa Cruz Island
- Hostel rentals Santa Cruz Island
- House rentals Santa Cruz Island
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- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes