House vacation rentals in Rochester

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Popular amenities for Rochester house rentals

House rentals with free parking

Guest favorite
A light-filled living area features two leather couches and a reclining chair. Soft gray carpet complements the light walls, while large windows are dressed with flowing curtains. A coffee table with a glass top sits in front of the seating arrangement, creating a cozy gathering space.
Home in Rochester
4.87 out of 5 average rating, 38 reviews

2 Bedroom Apartment, Walk To Mayo, Free Parking

BradyRating, 5 stars2 weeks ago
This was the nicest place I’ve stayed at and I would recommend it to anyone going to Rochester!
Top guest favorite
Home in Rochester
4.98 out of 5 average rating, 133 reviews

☆Dee Dee's Den a Dharma Dwellings Parent Company☆

ArikRating, 5 stars3 weeks ago
Alex and Emily were amazing hosts for our weekend stay in Rochester. My mom is hopitalized at St. Mary's of Rochester since March 25th, 2025. My sister and I had been staying in hotels and my wife would come on the weekends and we would have to find a place for our two dogs to be. Dharma Dwellings was the answer for us to all be reunited on the weekend and had amazing accommodations. It was a quick 10 minute drive to the hospital and for us to get back during the day to take the dogs on a walk. Our two dogs were as comfortable as being home and the area was great for taking them on walks and getting their energy out while we would visit the hospital during the day. The kitchen allowed us to make home cooked meals. There are alot of great restaurants in Rochester, but this allowed us to just relax at eat at the house. I feel like I am rambling but I will try to wrap it up quick, the amazing features of two living rooms, comfortable and spacious beds, two bathrooms made this stay amazing
Superhost
The kitchen features wooden cabinetry and stainless steel appliances, including a refrigerator and oven. A central island with seating for three is present, complemented by an adjacent window allowing natural light. The floor is tiled, and additional storage options are available.
Home in Rochester
4.96 out of 5 average rating, 27 reviews

Your Stay Steps Away - 719 1/2 Mayo Discount!

TinaRating, 5 stars10 months ago
The house was great. It had everything we needed and more. Very kid friendly and the kids loved the trail in the back as well as catching fireflies at night. Broc responded to every message timely and was very helpful. I would definitely stay here again if I was in the area.
Top guest favorite
A dining room is shown, featuring a wooden table that accommodates eight seats. The space is illuminated by ceiling lights, and large windows are adorned with wooden trim, providing natural light. A neutral-colored wall art piece adds a touch of decor.
Home in Rochester
5 out of 5 average rating, 17 reviews

Mayo Clinic • 3 King bed • 2 Full Bath • Free Park

MichelleRating, 5 stars3 weeks ago
Plenty of space for everyone. Beds were super comfortable. Had everything we needed for our stay. Upgrades to the house were done very nicely. Plenty of outside space for the kids. We had a very enjoyable stay.
Superhost
A cozy living area features a gray futon with red accent pillows, positioned across from a dark wooden coffee table. A patterned area rug lies on the floor, complemented by a pair of cube stools. Light enters through two windows with blinds, enhancing the warm atmosphere.
Home in Rochester
4.85 out of 5 average rating, 33 reviews

Snow Kist House

CynthiaRating, 5 stars3 months ago
The house was warm and cozy. Safe neighborhood. The house supplied everything we needed.
Superhost
A cozy living area is depicted, featuring a gray sofa with decorative pillows and a bright yellow armchair. A small round table with a vase sits in the center. Windows dressed with patterned curtains allow natural light to fill the space, accented by a soft area rug.
Home in Rochester
4.83 out of 5 average rating, 495 reviews

Cozy home next to Mayo Clinic & historic parks!

MariaRating, 5 stars2 weeks ago
Wonderful cozy little house for relaxing and de-stressing after a hectic day at Mayo Clinic for my followup appointment. Thank you!
Guest favorite
The exterior of the little blue house features a classic design with a sloped roof and multiple windows. A white picket fence encircles the front yard, which has a small garden area. The surrounding buildings in the background suggest a vibrant neighborhood near the Mayo Clinic.
Home in Rochester
4.92 out of 5 average rating, 148 reviews

Cheerful 3-bedroom home across St. Mary's Campus.

MaloriRating, 5 stars1 month ago
Our stay was great! We were being seen at Mayo Clinic and when our trip got extended last minute, this place was a great option to accommodate what we needed. Super walkable (if you are able) across the street to St. Mary’s campus!
Top guest favorite
A cozy family room features a comfortable sectional sofa and a wooden coffee table, complemented by a stone fireplace. A large television is mounted on the wall, while natural light fills the space through wide windows with blinds. Decorative shelves display various items.
Home in Rochester
5 out of 5 average rating, 15 reviews

AlloroHome| 2 BR, 1mi to MayoClinic StMarys Campus

StephenRating, 5 stars4 days ago
Excellent place to stay for a visit to Mayo. I brought a family member to Rochester for a few appointments at Mayo Clinic and stayed here at Joel & Carla's place. The hosts were very easy to communicate with, and stay was perfect. The house matched all the descriptions and felt even nicer than expected, and it was in a neighborhood that felt nice and quiet, while being very easy to get to/from Mayo each day. I would definitely recommend it and would stay here again.

House rentals with a pool

The living area features a high wooden ceiling and a prominent stone fireplace surrounded by mounted trophies. Large windows invite natural light and provide views of the outdoors. A comfortable seating arrangement is present, accompanied by a dining table visible in the background.
Home in Alma
4.77 out of 5 average rating, 13 reviews

The Shack

JessicaRating, 5 stars8 months ago
The Shack was exactly what we needed for a quick family getaway. We appreciated the tranquility and scenery of the countryside with the convenience of being just minutes away from restaurants and a picturesque distillery. Our daughters loved the treehouse, slide, and pool. They want to visit again but stay longer next time. :-) Tim was great to work with, attentive and helpful.
Guest favorite
A charming bungalow features a welcoming front porch with yellow chairs and a small table. The house is painted in a dark color with white accents, showcasing large windows on the second floor. A well-maintained lawn is visible, providing a spacious outdoor area.
Home in Lake City
4.87 out of 5 average rating, 15 reviews

3 Bedroom home (sleeps 8)

DustinRating, 5 stars3 months ago
Great place! Great views and very comfortable for our group of 8. Provided room to be together and space apart for individual quiet time if desired. Well appointed and well taken care of. Beau was very responsive, accommodating, and super friendly! This is our new go-to spot when visiting LC. Definitely recommend!
Guest favorite
An indoor pool area features a heated, endless pool with steps leading into the water. Large windows provide views of the surrounding greenery, and a plant sits beside the pool. A ceiling fan contributes to ventilation in the space.
Home in Wabasha
4.97 out of 5 average rating, 69 reviews

Indoor pool-Arcades-Amazing Views!

PatRating, 5 stars4 weeks ago
Checking in to Erin's house was very easy. She is very easy to communicate with. Soon after checkin, Erin messaged us to make sure everything was in order and to see if we had any questions. The views are absolutely amazing. From the moment we booked the house I couldn't wait to enjoy coffee in the sunroom. It did not disappoint. The sunroom has heated tile floors and a small wood burning fireplace. So cozy! The pool and pinball machines were a big hit for the kids. We would definitely recommend staying here!
Top guest favorite
Two individuals are seated in a green float in the expansive pool, overlooking a vast landscape. The sun shines brightly above, casting reflections on the shimmering water, while rolling hills and trees extend into the distance.
Home in Rochester
5 out of 5 average rating, 38 reviews

RARE! Pool, hot tub, garden &chickens! 4m to Mayo

LezliRating, 5 stars3 months ago
Tiffany’s place was a great location for our annual girls weekend trip. We loved taking advantage of the hiking trails, hot tub and fireplace! The space was perfect for 7 adults, and we enjoyed our time. This is not a complaint but just a heads up for future guests - there is only a Keurig, no coffee maker. We’re big coffee drinkers, so we had to pivot a bit but it was no big deal. 😊 Thanks Tiffany!
Superhost
The spacious living area features exposed wooden beams and a stone fireplace, providing a focal point. A modern sectional sofa is arranged near a small dining area, with natural light streaming through large windows. An open layout enhances the feeling of airiness.
Home in Rochester
5 out of 5 average rating, 3 reviews

Unit 2365J | 2bd/2bth | Single-Family Home

JoRating, 5 stars3 weeks ago
For an extended stay, this home fits the bill. It is in a very handy location with restaurants, grocery stores, gas stations, etc., only a few blocks away. The home is new & in a new area, where the properties are nice , very well maintained & managed. Allison, our coordinator did a very good job of answering our questions any time we called her . If available, we would definitely stay there again should we ever need an extended stay in Rochester.

Weekly house rentals

Superhost
A spacious bedroom features a comfortable bed with light-colored linens. Two bedside lamps provide soft lighting. A large artwork hangs on the wall, and a storage unit is visible beneath the television. A door leads to a hallway, enhancing open space.
Home in Rochester
4.77 out of 5 average rating, 13 reviews

Spacious Single Level House with Power Recliners

DebRating, 5 stars8 months ago
Jill’s place was just as described. It was immaculate, I am extremely picky about things being clean and Everything was spotless. Jill was extremely helpful with any questions and the place is perfect for resting in between apts. her guide to the area was helpful and we would absolutely stay there again!
Guest favorite
An inviting living room features a dark sofa, a patterned armchair, and a coffee table at its center. Artwork adorns the walls, while light streams in through a window covered with curtains. A cozy area rug adds warmth to the wooden floor.
Home in Rochester
4.93 out of 5 average rating, 45 reviews

Come From Away!

KarlieRating, 5 stars1 month ago
Jaymi's place was exactly what my family needed. We traveled 7 hours to get there and arrived a bit early. Jaymi was quick to respond to my request for an early check-in, and everything was perfect for our time in Rochester. The finished basement provided a home away from home feel for me and my husband, while my parents were very comfortable on the main level. When you're in Rochester for Mayo clinic appointments having a peaceful place to lay your head at night is important and Jaymi provided everything we needed to be comfortable.
Guest favorite
A welcoming living room is highlighted by a vibrant flower arrangement on a gold side table. A cozy couch faces a fireplace, with a television mounted above a white entertainment center. Musical decor and seasonal garlands add a touch of charm to the space.
Home in Rochester
4.88 out of 5 average rating, 16 reviews

Discount Charming 2 Bedroom Close to Mayo

MarionRating, 5 stars2 weeks ago
Was a lovely stay. Would definitely stay again. Very cozy quiet and close to everything I needed. 5 star stay. The bed was worth the whole stay.
Superhost
A single-story house is surrounded by manicured grass and shrubs. A paved driveway leads up to the home, featuring large windows and a covered porch. A two-car garage stands to the side, accompanied by tall trees casting shade in the background.
Home in Rochester
4.68 out of 5 average rating, 41 reviews

House for Rent Close to Mayo Clinic & St. Mary's

HannahRating, 5 stars3 months ago
Bao was incredibly responsive to all of my communication. The house was exactly as listed, with three bedrooms on the ground floor (3 stairs to entrance), an upstairs bathroom with tub, a bed in the basement, and a second bathroom in the basement (shower stall format). Laundry worked well. Furniture was comfortable. Easy walk or drive to Mayo hospital (St. Mary's) and close to park trains that offered miles of walking along the river. Met all of our needs completely.
Guest favorite
A spacious living area features a stone fireplace as a focal point, with a mounted television above. Comfortable leather sofas are arranged around a large, rectangular coffee table. Natural light filters in through windows, contributing to an inviting ambiance.
Home in Rochester
4.96 out of 5 average rating, 70 reviews

Luxury Home - Newer Construction - 3 BR/2 Bath

AlisonRating, 5 stars1 month ago
This is our second visit to Sarah’s beautiful home with our pups. We so appreciate all the beautiful furnishings and how much it feels like home. We love to cook all our meals and enjoy family movie time. The kitchen is so well appointed and open to the great room that it makes for fun downtime. We will always check to see if this wonderful rental is available when we are in town. Thanks to Sarah for the early check in as well! Great property and host!
Superhost
Home in Rochester
4.6 out of 5 average rating, 5 reviews

Ideal Location Near Mayo & St. Mary's *6 bedrooms*

LarissaRating, 5 stars60 months ago
This house was spectacular! The space energy feels so good. I loved cooking in this kitchen and the bed was so comfortable! These hosts we amazing at communication and getting us all the information we needed. The location was so convenient to Mayo and all the special touches made our week way nicer. We will absolutely stay here again!
Superhost
A living area features two gray sofas with decorative cushions, arranged around a patterned area rug. A small table with a plant sits between the sofas. The walls are painted in a soft gray tone, and a floral artwork adds a touch of color.
Home in Rochester
4.88 out of 5 average rating, 33 reviews

Lake Cottage-4 Mins to Mayo. Main floor beds/bath.

TimRating, 5 stars7 months ago
Your home was the perfect place for our recent visit to Mayo Clinic. The fenced back yard was perfect for our dog and the access to the walking trails was an added bonus.
Guest favorite
Home in Rochester
4.83 out of 5 average rating, 36 reviews

The Loft & Nook: Modern Comfort + Spacious Livin’

JenniferRating, 5 stars3 months ago
Loved how this home was decorated and it was so spacious!! Loved our stay. Close to trails and in a nice neighborhood.

Quick stats about house rentals in Rochester

  • Total rentals

    420 properties

  • Total number of reviews

    20K reviews

  • Family-friendly rentals

    320 properties are a good fit for families

  • Pet-friendly rentals

    120 properties allow pets

  • Rentals with dedicated workspaces

    300 properties have a dedicated workspace

  • Wifi availability

    420 properties include access to wifi

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