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House vacation rentals in Panama

Find and book unique houses on Airbnb

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Popular amenities for Panama house rentals

House rentals with a pool

Superhost
Home in Río Hato
4.83 out of 5 average rating, 6 reviews

Beach villa with cozy terrace

Lakshmi MaytrejaRating, 5 stars8 months ago
As you see it in the photo it is, just perfect. I recommend EVERYTHING and we will always come back
Superhost
Home in Playa Venao
4.83 out of 5 average rating, 12 reviews

Modern Beach Home with pool and hot tub

AndriusRating, 5 stars11 months ago
🤙
Guest favorite
Home in Panama City
4.94 out of 5 average rating, 34 reviews

Nice duplex house with a swimming pool.

SeanRating, 5 stars1 month ago
Panama is a beautiful country with many beautiful people, Gerardo is definitely one those people. He was fun, polite, helpful and understanding. He was a wealth of knowledge with good intentions, we found some great locations because of him. The house was perfect for us, spacious rooms, beautiful decor, relaxing balcony and a wonderful backyard pool. The location was Uber friendly and safe to walk and relax. When we return to Panama, Gerardo and his place will be on top of the list. ❤️
Superhost
Home in Bocas del Toro Province
4.91 out of 5 average rating, 87 reviews

Casita Chalet Tropical with Swimmingpool

BijayaRating, 5 stars1 month ago
Míriam has been an impeccable host, always ready to give good advice, it was easy to communicate with her. The corner that they mounted is proper those we expected, total immersion in nature, birds chants, clean as ever (all the islands have us schocked by the garbage there is everywhere), return to the chalets and feel at ease as if we were at our house has been super cool. We advise you to rent a motorbike to ungubrate the islands !!
Superhost
Home in David
4.68 out of 5 average rating, 38 reviews

Casa Piscina - House with a pool in David

GtRating, 5 stars5 days ago
Walter went over and above recommending several areas, restaurants, grocery stores, etc during our visit. He was always available if anything was needed. The pool was our favorite and very refreshing after spending the day touring areas around David, Boquete, Volcan and other areas.
Superhost
Home in Nueva Gorgona
4.89 out of 5 average rating, 47 reviews

Large private house with pool (Late check-out)

Abraham AbdelRating, 5 stars1 month ago
Great location, very clean house, had everything you need in the kitchen area, would definitely go again
Guest favorite
Home in Río Hato
4.87 out of 5 average rating, 90 reviews

Poolside Paradise in Santa Clara

JuanRating, 5 stars1 month ago
Phillip and his team are always very attentive to those staying in their facilities. They care because you have a great time.
Guest favorite
Home in Las Lajas
4.82 out of 5 average rating, 49 reviews

Relax and Unwind at Las Lajas Beach House

ValérieRating, 5 stars1 month ago
The beach was incredibly beautiful! Super wide, few people. Super safe swimming despite the waves. Amazing sunset & sunrise 🤩 Free beach access and 5-10 min walk

Weekly house rentals

Superhost
Home in Las Lajas
4.79 out of 5 average rating, 14 reviews

Perfect Getaway Mountain like House with pool

AntonioRating, 5 stars2 weeks ago
We stayed 3 days and had a great time. The place is totally relaxing and ideal to disconnect. 5 minutes from shops in Coronado. A large pool that adults and children enjoyed. A spacious kitchen with lots of natural light. Good air conditioning in the bedrooms and with good WiFi signal inside and outside the house. Roger was attentive to our arrival and gave us the access directions.
Guest favorite
Home in Playa Venao
4.89 out of 5 average rating, 19 reviews

Next to Beach Club: Blue 2 Bedroom Family Villa

AimeeRating, 5 stars4 months ago
This villa in Blue Venao was exactly as described—clean, comfortable, and as close as you can be to the beach / beach club restaurant. Dorian was very communicative about what to do in Venao. This villa had everything we needed and was well stocked - absolutely no complaints. Beds were comfortable, and the living area big enough for our small family. Great outdoor space but unfortunately with the rain we weren't able to use it. We were here from Saturday to Monday. If you are coming during the week, you might there is was noise from the duplex buildings construction right out front of this villa, which may be disruptive if you’re looking for a quiet stay (Blue Venao is a growing property). That said, it didn't bother us when we were inside (didn't hear a thing) - everything else was amazing, and we were fortunate to enjoy coffee and watch the guacamayas outside in the tree above.
Guest favorite
Home in Boquete District
4.97 out of 5 average rating, 29 reviews

Casa Tropical Boquete - Family Home

MarkRating, 5 stars3 weeks ago
Super helpful and kind hosts. We stayed her 8 nights and had an excellent time. When we fell ill, the hosts even offered to get medicine for us from a pharmacy. Interior and exterior of the unit is lovely. Hosts have lots of local knowledge. Can’t recommend highly enough.
Guest favorite
Home in Panama City
4.93 out of 5 average rating, 14 reviews

LovelyviewPty House 15 minutes away from the airport

GeorgeRating, 5 stars1 month ago
Nice clean house. Felt just at home, excellent view of the city. Had everything I needed and my family enjoyed staying there. Would stay there again if I visit Panama.
Superhost
Home in Panamá
5 out of 5 average rating, 3 reviews

Airbnb - Amazing - Rest - Villa

EduardRating, 5 stars3 weeks ago
Mike exceeded our expectations making our stay very comfortable. Nice pool! Safe neighborhood!
Guest favorite
Home in Panamá
4.9 out of 5 average rating, 31 reviews

Home Harmony M&M

AdrianaRating, 5 stars2 months ago
Thank you Lila for your attentions. I was ready the beds for two people and they were for 3 and she was very friendly accommodating for the 3 person. A very cozy place. Ideal for short stops in Panama
Guest favorite
Home in Bocas del Toro
4.92 out of 5 average rating, 25 reviews

Architectural Waterfront Home - "Casa Comunal"

FrankRating, 5 stars1 month ago
Fantastic place, the sea is your backyard. Monkeys, tracking, squirrels, and surfers on the waves passing by. Great house, minimalist but very nice with various hangouts. Keep in mind that it can be warm in the house and that insects can easily enter....but there is something great about that.
Superhost
Home in Bocas del Toro Province
4.87 out of 5 average rating, 125 reviews

Casa Clearwater... Your Caribbean Dream

GmiRating, 5 stars1 month ago
We had a fantastic time ! We will be back

Private house rentals

Guest favorite
Home in Nueva Gorgona
4.95 out of 5 average rating, 19 reviews

Spectacular property with beach access

NolanRating, 5 stars1 week ago
Had a really great time staying with Adrian. Residence is very quiet, secluded, and had great beach access. Adrian and Rogelio were both very responsive, helpful, and friendly. They went above and beyond to make our stay as nice as possible. Would highly recommend staying here with Adrien!
Superhost
Home in Colón
4.83 out of 5 average rating, 40 reviews

Family style living and close to the Panama Canal

EmmanuelRating, 5 stars6 months ago
Great place, great people and calm, quiet area, everything went as smoothly as possible. Will stay again when visiting Colon.
Superhost
Home in contadora
4.85 out of 5 average rating, 212 reviews

villa in contadora, las perlas

SteffiRating, 5 stars2 weeks ago
We loved it! Relaxing and fun. The host had everything from transportation to activities and restaurants covered . The only issue we had is because of our age and mobility issues. We are not agile enough to manage the stairs at night and although there are two queen beds upstairs, there’s only one bathroom in the master bedroom. The staircase is narrow and not easy to manage at night. We ended up using the sofa bed to be closer to a bathroom. But we were without privacy and our bags were in the living room It worked Maritza is amazing and didn’t kick us out early we were able to enjoy every minute Of our stay on the Island until 2pm when we went to the Dock to get the ferry
Superhost
Home in Cacique
5 out of 5 average rating, 3 reviews

House in Cacique- Jungle and Sea

MariabelRating, 5 stars11 months ago
We loved our stay at Finca Cacique. It is highly recommended. The house is lovely and feels like home. We were fascinated by the sustainable decoration as everything that could have been plastic, was made of wood instead! You get the best of both worlds as the house is surrounded by nature and about 10 mins walk you can find the little colourful Cacique town where there are boats that can take you in 5 mins to beautiful nearby islands. A small beach is close too, but we'd still recommend to you the islands, so make sure to bring some cash. Ana and Mainor were really nice and attentive to us, and we really appreciate it. We are surely coming back again!
Superhost
Home in Coronado
4.71 out of 5 average rating, 104 reviews

Private Home in Gated Beach Community with Pool

AlessandraRating, 5 stars2 months ago
We had a nice family time at Lorena's house. The space is cozy, with spacious rooms and an external area to enjoy with friends and prepare an asado. The condominium pool has bohíos, allowing you to cool off while relaxing in a very nice atmosphere. The place is a perfect escape for a quiet vacation! Thank you Lorena. I wish we can return soon!
Guest favorite
Home in Anton Valley
5 out of 5 average rating, 42 reviews

Beautiful Country House

KyleRating, 5 stars3 weeks ago
Truly stunning house! We came with our in-laws and my three boys and had a truly outstanding time. The house was beautiful and perfect for spending days exploring, hiking, cooking, and enjoying the views. I don’t think you’ll find much better! The house was incredible and the hosts were super communicative and supportive. Highly recommended
Superhost
Home in Alto Boquete
4.66 out of 5 average rating, 59 reviews

Fresh and Comfy - Van Tonder's house near Boquete

MichaelRating, 5 stars2 days ago
We were a team of 8 riders that traveled from Veraguas to Chiriqui to participate in a horseback endurance race. The house was located close to where we kept the horses and was the perfect for our group. Everyone had their own comfortable bed. We cooked breakfasts and dinners, which was so convenient. The kitchen had all the supplies we need. Great stay for our purposes!
Superhost
Home in La Guaira
4.68 out of 5 average rating, 73 reviews

Villa Mar y Luna

Holdemar JaelRating, 5 stars1 month ago
Second time in this place and I still think it is a small piece of heaven on the middle of the beach

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