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House vacation rentals in Panama

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Top-rated house rentals in Panama

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Home in Bocas del Toro

4.85 out of 5 average rating, 136 reviews

Architectural Waterfront Home- "Casa Sur"

As seen on the leading modern architecture site, Dwell! Casa Sur is half of Casa Comunal, a rustic home on the Caribbean beachfront. It shares a roof & entryway room w/ Casa Norte, our other listing, but separated by 2 sliding walls for total privacy. Lush gardens, fruit bearing trees, designed for surfers, snorkelers, yogis, with a massive deck & private sand beach. Mid-Century interior designs handcrafted by local artisans, stunning textiles, a sustainable rainwater catchment system & more.

Home in Costa Esmeralda

4.97 out of 5 average rating, 134 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise. Majestic Sands is located in a private beach community in Costa Esmeralda, San Carlos District, Panama. It is located a few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, Santa Clara and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.

Home in Bastimentos

4.81 out of 5 average rating, 107 reviews

Spacious, Over the Water Home with Plunge Pool

Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to restaurants, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.

Home in Pedasí

4.94 out of 5 average rating, 145 reviews

3 min to Pedasi, 5 min to the Beach, Private Pool!

Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

Home in Los Algarrobos

4.97 out of 5 average rating, 112 reviews

Cozy and relaxing house with terrace

Relax with the whole family in this quiet place, 10 minutes from the center of David and 25 minutes from the tourist Boquete, very close to shopping centers, restaurants, but away from the hustle and bustle of the city. Very safe place and full of amenities. The house has three bedrooms, 2 bathrooms, a living room, a dining room, a fully equipped kitchen and a beautiful terrace with TV, piano, a bar among other amenities. All spaces have aires conditioned, hot water and TV with 222 channels.

Home in Jaramillo

4.95 out of 5 average rating, 129 reviews

Mountain house with beautiful views

Stay at in an exclusive location with gorgeous views, cool weather, lovely gardens and peaceful environment but near Boquete center. Casita Jaramillo is a mountain guest house, nested in a 2,5 acre property at quiet Jaramillo mountain. You will be surrounded by tall trees, singing birds, clean air and nature sounds but you can reach busy Boquete after a ten minute drive and enjoy restaurants, shops and endless variety of outdoor activities. Access road is paved and 4WD is NOT neccessary

Home in San Carlos

4.94 out of 5 average rating, 100 reviews

OceanView-Rooftop Jacuzzi&Pool | Concierge Service

Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 7.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base price covers 4 guests (additional charge $40 per person). Sleeps up to 25 guests.

Home in Bocas del Toro District

4.92 out of 5 average rating, 211 reviews

Orange House - Over The Water Rentals

Enjoy golden sunsets across the bay from the Orange House at Over The Water Rentals. Home away from home in a tropical paradise. Relax on your outdoor lounge or explore the bay. The house has snorkel gear, SUP's & kayaks for guests to use for free. Located close to town & airport in a quiet local neighborhood. The house features a king size master bedroom & queen guest room, spacious hot water shower, handmade organic toiletries, fully equipped kitchen & high speed wifi

Home in Taboga Island

4.97 out of 5 average rating, 159 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Home in Vista Mar Golf, Beach & Marina

4.88 out of 5 average rating, 236 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets. any inquiry please contact 66168596

Home in Las Colinas de Caceres de Arraijan

4.98 out of 5 average rating, 199 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Home in Altos del Maria

4.8 out of 5 average rating, 258 reviews

Modern House in Altos del Maria, Panama

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. It´s a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains.

Vacation rentals for every style

Get the amount of space that is right for you

Bungalows

Intimate homes. inviting architecture

Cottages

Quaint homes, peaceful surroundings

Chalets

Adventure-ready homes with après-ski style

Popular amenities for Panama house rentals

Free parking on premises

Air conditioning

House rentals with a pool

Home in Panama

4.96 out of 5 average rating, 142 reviews

Villa Isabella in Coronado Beach Panama

Home in Bocas Del Toro

4.96 out of 5 average rating, 99 reviews

Wiona of Villa Paraiso | Beachfront Villa & Pool

Home in Playa Venao

5 out of 5 average rating, 18 reviews

Nearly Oceanfront: Blue 3 Bedroom Spacious Villa

Home in Playa Hermosa

5 out of 5 average rating, 27 reviews

Entire house with private pool facing beach !

Home in Río Hato

4.93 out of 5 average rating, 29 reviews

Villa Santorini | Playa Blanca

Home in Bocas del Toro Province

5 out of 5 average rating, 28 reviews

The Pool House, Beach House on Paunch Beach

Home in Playa Bluff

4.93 out of 5 average rating, 29 reviews

Jungle House 100m from the beach

Home in Playa Venao

4.95 out of 5 average rating, 22 reviews

Casa Pelicano - Tropical house w pool and seaview

Weekly house rentals

Home in Altos del Maria

5 out of 5 average rating, 27 reviews

Portazul - A Mountain Retreat

Home in Santa Catalina

4.95 out of 5 average rating, 44 reviews

Casa Colibrí - modern house in the green

Home in Isla Carenero

4.94 out of 5 average rating, 17 reviews

Casa Blanca-Sea Views/outdoor living/walk to surf

Home in Nueva Gorgona

5 out of 5 average rating, 7 reviews

Spectacular Beachfront House

Home in Torio

5 out of 5 average rating, 14 reviews

Ideal Creative Retreat Immersed in Forest

Home in La Guaira

4.97 out of 5 average rating, 88 reviews

Puntita Manzanillo, fantastic sea and jungle

Home in Río Hato

5 out of 5 average rating, 13 reviews

Marina|garden|bbq|private pool

Home in Alto Quiel

4.89 out of 5 average rating, 36 reviews

Casita Colibrí - with beautiful mountain views

Private house rentals

Home in Bajo Boquete

4.99 out of 5 average rating, 68 reviews

Beautiful new house in Boquete

Home in Palenque

4.82 out of 5 average rating, 11 reviews

Caribbean Paradise - Beachfront Getaway

Home in Bajo Boquete

4.96 out of 5 average rating, 74 reviews

Spacious 3BR walking distance, close to everything

Home in Bajo Boquete

4.78 out of 5 average rating, 67 reviews

7 sketch mountain Jaramillo house upstairs Boquete

Home in Pedasí

4.9 out of 5 average rating, 42 reviews

Pedasí :Andromeda Boroda 4-6 p. Beach, swimm. pool

Home in Santa Fe

4.94 out of 5 average rating, 17 reviews

Santa Fe House with an amazing view

Home in Jaramillo Arriba

5 out of 5 average rating, 14 reviews

House in Boquete w/ King Beds, A/C & Hot Tub

Home in Bocas del Toro

4.89 out of 5 average rating, 9 reviews

Tropical Waterfront Home

Destinations to explore