
House vacation rentals in Panama
Find and book unique houses on Airbnb
Top-rated house rentals in Panama
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama house rentals
House rentals with a pool

Beach villa with cozy terrace
As you see it in the photo it is, just perfect. I recommend EVERYTHING and we will always come back

Cheerful Casa Duplex with swimming pool.
Panama is a beautiful country with many beautiful people, Gerardo is definitely one those people. He was fun, polite, helpful and understanding. He was a wealth of knowledge with good intentions, we found some great locations because of him. The house was perfect for us, spacious rooms, beautiful decor, relaxing balcony and a wonderful backyard pool. The location was Uber friendly and safe to walk and relax. When we return to Panama, Gerardo and his place will be on top of the list. ❤️

Wiona of Villa Paraiso | Beachfront Villa & Pool
We have spent here approximately a week. It was a tropical paradise, no doubt. Jemina was wonderfully helpful, we needed something, she arranged it :) The ocean is nice (white sand beaches are in 30 minutes car + boat ride). Although you are a little far from the city the taxi network (which is basically messaging trough whatsup to drivers) works surprisingly well! We loved it.

Casita Chalet Tropical with Swimmingpool
Míriam has been an impeccable host, always ready to give good advice, it was easy to communicate with her. The corner that they mounted is proper those we expected, total immersion in nature, birds chants, clean as ever (all the islands have us schocked by the garbage there is everywhere), return to the chalets and feel at ease as if we were at our house has been super cool. We advise you to rent a motorbike to ungubrate the islands !!

Casa Piscina - House with a pool in David
We were received very nicely and the hosts were very nice and helpful. We had a great time and can recommend the location at any time.

Large private house pooled house (Late check-out)
Great location, very clean house, had everything you need in the kitchen area, would definitely go again

Poolside Paradise in Santa Clara
Phillip and his team are always very attentive to those staying in their facilities. They care because you have a great time.

Relax and Unwind at Las Lajas Beach House
We had a wonderful 3 night stay at Michael’s place. Very clean and a short walk to the beautiful Las Lajas beach. The pool was very refreshing and shaded during most of the day. Beds were all comfortable and plenty of towels including kitchen towels. We highly recommend this Airbnb and hope to stay here again.
Weekly house rentals

Surf Shangri-la in Bluff Beach
It was a great stay at Playa Bluff. We came with our son and we loved the house and the location, one minute from the beach. There are restaurants very close to eating, dining or having a drink but keeping the quiet character of the area. It's really a gem to enjoy nature. Nicole is a very kind and communicative host.

Perfect Getaway Mountain like House with pool
This is my second time in this place. I will come back again. The place has it all. Every time I go, I always extend my stay. I recommend it

Next to Beach Club: Blue 2 Bedroom Family Villa
This villa in Blue Venao was exactly as described—clean, comfortable, and as close as you can be to the beach / beach club restaurant. Dorian was very communicative about what to do in Venao. This villa had everything we needed and was well stocked - absolutely no complaints. Beds were comfortable, and the living area big enough for our small family. Great outdoor space but unfortunately with the rain we weren't able to use it. We were here from Saturday to Monday. If you are coming during the week, you might there is was noise from the duplex buildings construction right out front of this villa, which may be disruptive if you’re looking for a quiet stay (Blue Venao is a growing property). That said, it didn't bother us when we were inside (didn't hear a thing) - everything else was amazing, and we were fortunate to enjoy coffee and watch the guacamayas outside in the tree above.

Casa Tropical Boquete - Family Home
Jhayat and Abdul were great hosts! Place was just as described, peaceful and very well located. Beautifully kept place! Would definetely recommend while visiting Boquete.

LovelyviewPty House 15 minutes away from the airport.
Nice clean house. Felt just at home, excellent view of the city. Had everything I needed and my family enjoyed staying there. Would stay there again if I visit Panama.

Home Harmony M&M
Thank you Lila for your attentions. I was ready the beds for two people and they were for 3 and she was very friendly accommodating for the 3 person. A very cozy place. Ideal for short stops in Panama

Architectural Waterfront Home- "Casa Comunal"
Fantastic place, the sea is your backyard. Monkeys, tracking, squirrels, and surfers on the waves passing by. Great house, minimalist but very nice with various hangouts. Keep in mind that it can be warm in the house and that insects can easily enter....but there is something great about that.

Casa Clearwater... Your Caribbean Dream
We had a fantastic time ! We will be back
Private house rentals

Spectacular property with beach access
Adrien’s place is STUNNING! We absolutely loved our stay and are already planning to stay again soon! The view is incredible and the property is very well taken care of. Rogelio is one of the kindest hosts and he went above and beyond to make our stay comfortable and memorable. The kitchen is well stocked, the beach is quiet and pristine, and the internet is very strong. It is truly the perfect place to relax with family or work remotely. We also loved watching the iguanas all day! I cannot wait to come back again!

Family style living and close to the Panama Canal
Great place, great people and calm, quiet area, everything went as smoothly as possible. Will stay again when visiting Colon.

villa in counter, pearls
Vincent and his crew - Samuel and Maritza take very good care of his guests. Felt quite spoiled.

House in Cacique- Jungle and Sea
We loved our stay at Finca Cacique. It is highly recommended. The house is lovely and feels like home. We were fascinated by the sustainable decoration as everything that could have been plastic, was made of wood instead! You get the best of both worlds as the house is surrounded by nature and about 10 mins walk you can find the little colourful Cacique town where there are boats that can take you in 5 mins to beautiful nearby islands. A small beach is close too, but we'd still recommend to you the islands, so make sure to bring some cash. Ana and Mainor were really nice and attentive to us, and we really appreciate it. We are surely coming back again!

Private Home in Gated Beach Community with Pool
Really enjoyed the peace and quiet here! The place was easy to find and super spacious! The beach club is close and very private basically all to yourself!

Beautiful Country House
Really enjoyed the house & the location. Nice outdoor space in the main house & in the separate bbq/bar open air building. Also enjoyed sitting on two benches by the pond that had at least a half a dozen turtles swimming around. The bird life was splendid and added to spending time outdoors. The property is well maintained, and the landscaping was beautiful. Will definitely come back.

Fresh and Comfy - Van Tonder's house near Boquete
It is a really nice place, mostly all equipments are included and easy to use, lot of space to hang out and rest, the pool inside really have a nice touch, a little safety on the borders would be better but its really a good location to be.

Villa Mar y Luna
Second time in this place and I still think it is a small piece of heaven on the middle of the beach
Destinations to explore
- Beach condo rentals Panama
- Pet-friendly rentals Panama
- Rentals with beach access Panama
- Rentals with breakfast Panama
- Smoking-friendly rentals Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Farmstay rentals Panama
- Nature eco lodge rentals Panama
- Rentals with an accessible height bed Panama
- Hotel rentals Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Beach house rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Rentals with a sauna Panama
- Loft rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Kid-friendly rentals Panama
- Waterfront rentals Panama
- Rentals with a fire pit Panama
- Lakehouse rentals Panama
- Rentals with a home theater Panama
- Rentals with a fireplace Panama
- Chalet rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with pools Panama
- Boutique hotel rentals Panama
- Boat rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Monthly Rentals Panama
- Bungalow rentals Panama
- Townhouse rentals Panama
- Fitness-friendly rentals Panama
- Rentals with lake access Panama
- Rentals with a hot tub Panama
- Bed and breakfasts Panama
- Cottage rentals Panama
- Family-friendly rentals Panama
- Apartment rentals Panama
- Island rentals Panama
- Treehouse rentals Panama
- Villa rentals Panama
- Condo rentals Panama
- Tiny house rentals Panama
- Rentals with a patio Panama
- House rentals Panama City
- House rentals Colón Province
- House rentals Playa Coronado
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes