Guesthouse vacation rentals in Panama

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Panama

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in El Valle de Antón

4.89 out of 5 average rating, 63 reviews

Private 1 BR cottage near India Dormida hiking

This fully equipped 1 bedroom cottage has been a high rated Super Host Airbnb favorite for 5 years. It now has an equally fabulous new owner and Airbnb requires a fresh start. Relax into the hammocks in this peaceful residential setting where birds and butterflies abound. The cottage opens to a wonderful private garden sitting area and gives you a fantastic view of India Dormida mountain and nearby hiking trail. A short (~1 mile) walk to the town with shops, restaurants and daily Farmers Market.

Superhost

Guesthouse in Los Naranjos

4.93 out of 5 average rating, 220 reviews

Sunshine Cottage at Finca Katrina

Sunshine Cottage is a little cottage in the back garden of Finca Katrina. It is set on a hill with views of Palo Alto and Jaramillo with a coffee plantation in the foreground. There is a full (double) bed, room to hang your clothes and to store your belongings. You have a small fridge, toaster oven, sink, coffee maker, and cupboard space for food, but no stove top. If you are looking for more bedrooms, there are additional units on Finca Katrina that compliment Sunshine Cottage. Send us a note!

Guest favorite

Guesthouse in Boquete

4.82 out of 5 average rating, 67 reviews

Rustic Private Studio Near Downtown

Please note that the cabin is conveniently located near the main street, which can occasionally result in some street noise. Rustic Cabin Small rustic cabin, ideal for individuals or groups of two seeking a place to stay while exploring Boquete. The property features on-site parking and easy access to the town center, whether by walking or by car. It is conveniently located near a large supermarket and easily accessible by bus. Situated on the second story, it has a completely private entrance.

Top guest favorite

Guesthouse in San José

4.96 out of 5 average rating, 27 reviews

Guesthouse in Punta Barco Resort

Guest house in Punta Barco Resort with access to 2 pools and private beach (nearby Coronado). The separate entrance accessible two-story guest house has both a sleeping area (downstairs) and a living area (upstairs). The 1st pool is right in front of your guest house. The 2nd communal resort pool with stunning sea views is located next to the resort's private beach within the resort complex and can be reached in a short drive by car. The use of the beach depends on the weather and the tides.

Top guest favorite

Guesthouse in Torio

4.91 out of 5 average rating, 132 reviews

Torio guesthouse with panoramic view

Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.

Guest favorite

Guesthouse in Rio Hato

4.89 out of 5 average rating, 96 reviews

Sustainable Guest house with Pool in Rio Hato

Discover Rancho Ahome, a serene 2BR 1Bath guesthouse in Rio Hato. Escape to tranquility, 5 mins from stunning beaches, and enjoy our private pool with a waterfall. Immerse in nature on our sustainable farm, home to fruits, rabbits and chickens. Perfect for those seeking peace and an eco-friendly retreat, Rancho Ahome offers a blend of comfort and adventure amidst breathtaking landscapes. Experience a peaceful sanctuary that’s close to nature yet filled with comfort. We are pet friendly.

Guest favorite

Guesthouse in Bocas del Toro

4.91 out of 5 average rating, 55 reviews

The Boat House in Big Bight

Come relax in this peaceful over the water ECO bungalow on Isla Colon, on a coral reef 15 minutes away from town BY BOAT ONLY.. See lots of stars in the sky, tons of sea life & stunning sunsets from your balcony! Enjoy Starfish Beach, just a 5 minute boat ride away. Red Frog Beach, Playa Bluff, Zapatillas, & much more while you're here in Bocas Del Toro! (Kitchen is provided with basic cooking essentials & bathroom with basic personal items).

Guest favorite

Guesthouse in La Ermita de San Carlos

4.96 out of 5 average rating, 126 reviews

Rural w/ comfort: AC, WiFi, pool, hot water.

The Small House is part of 5 cabins called “A Piece of Paradise” plus the House where the hosts live; Registered in the Panamanian Tourism Authority Bureau. ✸ Ideal for a couple or a single person ✸ Outdoor dining area and hammock ✸ Very quiet neighborhood ✸ Private and public transportation available, just ask and we will help you ✸ 7-10 minutes, by car, from Playa La Ermita and 10 minutes from Playa El Palmar (great spot for surfing)

Superhost

Guesthouse in La Loma

5 out of 5 average rating, 3 reviews

Beachfront Private Studio, Ground Level in Jungle

Private Studio Suite on the ground level of our guesthouse with STARLINK WIFI. A backup internet provider if required. Backup power generator. Top quality queen size bed. It's perfect for relaxing, enjoying the sounds of the jungle and ocean without neighbours, roosters, barking dogs or traffic. Only a few steps away from our 1 Km sandy beach. Next to Surfing Beach. Pool access all day long.

Guest favorite

Guesthouse in El Valle de Antón

4.8 out of 5 average rating, 10 reviews

El Valle Casita

Newly renovated casita located in the highly sought after Capirita neighborhood. Enjoy cooking in your own kitchen after a nights rest in a queen size bed, and relaxing on your private porch with a cup of coffee. We are close to town and hiking trails, you can enjoy shopping or local restaurants as well as burning some calories and enjoying Panama.

Top guest favorite

Guesthouse in Alto Boquete

4.88 out of 5 average rating, 24 reviews

Villa Castillo Bungalow, Boquete.

Visit Boquete with the family. We are located in Volcancito, 1,140 meters above sea level, with a cool climate, surrounded by gardens for a great experience with nature, a 5-minute drive from downtown Boquete, where you can enjoy cafes, restaurants, shops, hiking, coffee tours, honey tours, and many more activities.

Superhost

Guesthouse in San Carlos

4.75 out of 5 average rating, 8 reviews

(5) The Beach House Inn - The Santa Cruz Room

The Santa Cruz Room offers a clean, safe and serene rest just a short walk from the beach. This room offers your own private entrance, a double bed, coffee maker and sink and full private bathroom. Walking time in minutes... The Beach: 3 San Carlos village: 7 Vista Mar Marina: 15 El Palmar (surfing): 15

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What guests are saying

The Retreat in El Valle - Garden House

5 out of 5 average rating, 18 reviews1 day ago

We stayed only one night in the casita. It was really peaceful and the surroundings with the garden were beautiful. We wish we could have stayed longer to enjoy everything. Laura and Clare were great hosts. Very friendly and helpful with any recommendations in the area.

Guesthouse in El Valle de Antón

What guests are saying

Cosy, Private, Guesthouse, Pool, Central Local

5 out of 5 average rating, 4 reviews27 months ago

We had a delightful time. The accommodations were great with plenty of patio and pool and sun and shade. The location suited our purposes. This small town--not a tourist destination--gave us a launching pad for beach and mountain explorations plus a good place to hang out and walk around. George & Luce were gracious hosts, and generous with their time and extras. We now have a fond spot in our hearts for Villa Rosario.

Guesthouse in Villa Rosario

What guests are saying

Bocas Bay Lodge - Luxurious!

4.95 out of 5 average rating, 43 reviews1 month ago

What the hosts have created is a marvel of artistry and craftsmanship. The pictures do not capture the true magic of the place. From the beautiful gardens to the handcrafted furniture with simple and elegant attention to details. Far beyond our expectations. The hosts are kind, gracious and most welcoming. It’s a slice of heaven on earth.

Guesthouse in Valle de Agua

What guests are saying

Independent house located behind our house

4.95 out of 5 average rating, 55 reviews1 month ago

Carmen is a wonderful host. She and her family were so kind and helpful when I checked in. She made it easy to find the casita and helped me find the buses and places to shop for food and things I needed. The casita is small, but it has everything you need. There is hot water in the shower, an AC unit in the bedroom, and a kitchen with a stove, refrigerator, rice cooker, microwave, and all cooking utensils you would need. Carmen also provided some snacks and drinks, as well as coffee and tea, which I really appreciated when I arrived after a long day of traveling. The casita is very comfortable, and the neighborhood is lovely, with many trees and birds. Even without a car, it's easy to get around. You can walk about 10 minutes to the main road to catch buses to David or Boquete, or anywhere in between. It was also an easy 35 minute walk to David. I routinely walked to little shops, restaurants, and cafes along the main road. I stayed for a month and I would happily stay here again.

Guesthouse in David

What guests are saying

G Apartment/House for a violinist

5 out of 5 average rating, 7 reviews4 months ago

I love the apartment. Whenever I can, I come to spend a few days and leave totally renewed. The place is super quiet and the nature is wonderful. I walk and run along the beach and the dirt trails that border both the house and the beach. I relax in the hammocks, use the kitchen inside and the barbecue at night. At noon I like to go to a restaurant in the area. The layout of the spaces allows me to enjoy each environment and I enjoy the great opportunity to have work meetings away from the rest of the house. Chelín and Dany are splendid hosts, always with clear answers and goodwill. I definitely plan to return soon!

Guesthouse in Playa Los Destiladeros

What guests are saying

Tropical Lifestyle in Coronado Beach

4.83 out of 5 average rating, 6 reviews64 months ago

Why come to Panama? The friendly people? The breathtaking Mountain views? The gorgeous beaches? Yep! All of the above. You're going to find all that and more right here. A relaxing 5 minute walk and you'll be shedding your sandals to trod the amazing black sand beaches in your bare feet then taking a dip in the warm Pacific waters. Be sure to bring sunscreen and a 6-pack of Balboa or Panama cerveca to quench your thirst. Come back to the Beach House Coronado, rinse off, and walk into the cool water of the pool to get reinvigorated. Marie always has tunes going on the patio and their kitten will keep you entertained. Take a day and make the 45 minute drive up to El Valle and enjoy hiking, zip-lining, and the butterfly habitat. Grab a cheap, filling lunch at one of the local spots and slip into the market from some fresh (and cheap) produce to take back with you and whip up a delicious dinner in your well-stocked kitchen. The next day run over to Rio Hato and peruse the morning's catch at the fish market, come back and spend the afternoon by the pool and enjoy the tranquility that is Panama. You'll be safe, happy, and full of not only great food, but great memories.

Guesthouse in Coronado

What guests are saying

The Farmer’s Shack - Pure Nature

5 out of 5 average rating, 3 reviews14 months ago

The space surrounding the place was so beautiful and the property itself was very cozy. All the perfect spot to go as a couple. Mrs. Edisa and Silvia were very communicative at all times. Instructions were clear. The room is ideal for an intimate moment and disconnect. For now there is no internet for remote work, so you can disconnect to relax. It is an excellent place to share as a couple. I would have liked to stay to live hehe. We rest deeply. The patio is spacious and comfortable. Everything was very clean. I liked going out to the terrace to see the scenery. Just being in the house gives you peace. The terrain is also spacious but steep. Nice atmosphere. Cool during the day, cold at night. Silvia and Edisa always helped and responded quickly. We recommend arriving during the day to find the location well. At night it can be confusing, but we were able to get there without problems with a 4x4 car. The path for a sedan car is very intense.

Guesthouse in Rio Sereno

What guests are saying

Apartment accommodation near the beach and river

4.81 out of 5 average rating, 42 reviews3 months ago

Excellent host Mr Aristides was very attentive at all times. Regarding the place, super quiet in a quite central Casita of the beaches and main chame places. You arrive by taxi quickly anywhere. The Casita is very clean and comes with everything you need to cook there. 100% recommended

Guesthouse in Chame District

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