Hotel vacation rentals in Mississippi River

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Top-rated hotel rentals in Mississippi River

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Hotel room in Galveston

4.85 out of 5 average rating, 592 reviews

Grand Manor Luxury Suites- Vanilla Orchid Room

The elegant Grand Manor, built in 1905, a true southern tropical mansion. Luxurious amenities seamlessly blended with Victorian grace. Located in Galveston's East End Historic District & is considered one of the top architectural structures on the Island.Guest rooms are richly appointed, with king size beds. Private baths are Jacuzzi or claw-footed tubs. Best walking location B&B on Island . The beach,Funky bars & rooftop patios minutes away at WORLD FAMOUS STRAND . (2 other rooms available)

Guest favorite

The elegant lobby showcases a modern fireplace set within a classic mantel. Bright floral arrangements are placed on a low coffee table, complemented by a chic leather sofa and a plush blue armchair. The polished floor reflects the warm ambiance of the wood-paneled walls.

Hotel room in Bartlesville

4.88 out of 5 average rating, 41 reviews

Vintage Chic #102 - Hotel Phillips

Stay in the historic Hotel Phillips, with it's unique charm and beautiful historic architecture. Your stay will be enjoyable and relaxing, within our very clean and extremely affordable Hotel Phillips Modern Rooms. Our staff will assure your stay with us is pleasant and exceeds your expectations. If you are staying on business or just passing through Bartlesville, come check out what is happening at Hotel Phillips. Renovations are underway which allows us to offer such a great nightly rate

Guest favorite

A welcoming outdoor view is presented, featuring a well-maintained lawn with lush green grass, surrounded by trees. The building showcases a blend of outdoor seating and rooms, with a pathway leading through the property. A sign indicates a coffee stop is available for guests.

Hotel room in Detroit Lakes

4.9 out of 5 average rating, 184 reviews

Lakes Inn, On Detroit Lakes

Experience a relaxing stay steps in front the beach, flat-screen TVs, optional kitchenettes (for an additional fee). We welcome one pet per room for an extra fee (pets must not be left unattended). Complimentary kayaks and bikes, and visit Mi Cartagena Café, open daily from 7:30 AM to 6:00 PM, offering high-quality drinks and baked goods. Kindly refrain from bringing outside food or drinks to the cafe spaces deck as a courtesy to our business. For any assistance reach to Tim and Kerlis!

Guest favorite

A cozy bedroom features a spacious bed with crisp linens and a decorative throw. An accent wall in teal provides a calming backdrop, while large windows offer views of the historic building across the street. Soft lighting enhances the inviting atmosphere.

Hotel room in Duluth

5 out of 5 average rating, 6 reviews

NEW! Queen Suite , Walkable, + Great City View!

Our 2 Queen City Views showcase the wonderful Duluth Architecture! Located just across from Greysolon Ballroom and steps away from Lakewalk access, Duluth's Best Bread and Duluth Coffee Co 2 blocks away! It is hard to imagine staying elsewhere. Restaurants and activities galore, 1 mile to the DECC and 0.25 miles from Canal Park. book now! We have onsite parking available for sale after you book. See site for details. If you need special accommodations, please ask for Suite number 7.

Top guest favorite

A spacious studio-style suite features a king bed with white linens, accompanied by bedside lamps. A work desk and dining table for four are positioned across the room. A flat-screen television is mounted on the wall, with large windows allowing natural light inside.

Hotel room in Hot Springs

5 out of 5 average rating, 25 reviews

Historic Best Court 10, King and Queen Suite

Located near Downtown Hot Springs, this Mid-Century style space is retro chic! Built in 1933, this historic landmark was recently transformed into a hip and stylish destination. Our prime location is minutes away from the most popular attractions including the famous Bathhouse Row, North Woods Trail, Oaklawn Racing & Casino, Garvan Gardens, the Entertainment District and our Beautiful Lakes. Our friendly team is eager to help make your visit comfortable, memorable and special!

Superhost

A stylish bathroom features exposed brick walls and a large mirror above an ornate dark wooden vanity. A gleaming gold faucet complements the black countertop. A glass shower enclosure showcases a tiled interior, and a cabinet displays neatly folded towels.

Hotel room in Ripley

4.8 out of 5 average rating, 5 reviews

Inn On The Square - Room 2

An intimate three unit hotel catering to travelers of all ages searching for more than just a place to stay. Charm, sophistication, and comfort are achieved through a distinctive style with historic luxury grounded in southern hospitality. Sits in the heart of the Ripley Historical District. Once known as the Ripley Feed Seed, this 1903 building has been lovingly renovated, restoring much of its original charm and character. Stay for a weekend, or plan to stay for a week.

Top guest favorite

A private patio area features a comfortable chair next to a small table, with a potted plant on top. The entrance door is illuminated by warm lights, creating a cozy atmosphere. The walls are dark, contrasting with the light from the door and fixtures.

Hotel room in Mead

5 out of 5 average rating, 13 reviews

Reel Em Inn: Spacious Studio/ 1 Mile to Lake

Nestled just a mile from the lake, our cozy and clean rooms provide the perfect retreat for a relaxing getaway. Whether you're here to reel in a big catch or simply enjoy some time with friends, our budget-friendly accommodations make it easy to unwind. With a welcoming atmosphere and all the essentials you need, Reel Em Inn & RV Lake Texoma is the ideal spot to meet up, share stories, and create lasting memories. Come join us and make the most of your getaway!

Superhost

The hotel exterior features a classic late 1800's architectural style with a brick facade. Large windows provide natural light, while planters with greenery frame the entrance. The welcoming door showcases hotel signage, enhancing the inviting presence of the building.

Hotel room in Darlington

4.83 out of 5 average rating, 24 reviews

Driver Hotel, Room #1 - Newly Redesigned

This is a quaint 5 bedroom hotel built in the late 1800's. Totally updated to include an en suite bathroom in each room. These rooms are on the second floor, so it may not work for you if you have mobility issues. Each room has an antique wrought iron bed and immaculate sheets and bedding. We are within walking distance to eateries and across the street from the Tri-County ATV Trail. Parking available for trucks and trailers across the street.

Superhost

A modern living area is presented with tall windows dressed in sheer drapes, allowing natural light to fill the space. A colorful mural provides a focal point on one wall. Comfortable seating includes a neutral sofa, patterned ottomans, and stylish chairs, enhancing the inviting ambiance.

Hotel room in Milwaukee

4.8 out of 5 average rating, 10 reviews

King Deluxe

Our boutique guesthouse concept offers a personalized lodging experience you won’t find anywhere else. We offer guests authentic experiences that focus on modern luxuries, like the efficiency of self-check-ins, contactless service, beautiful spacious rooms with modern amenities, communal chef’s kitchens and the freedom to experience a property on their own terms. We do all that in carefully curated spaces that feel more like a home-away-from home.

Guest favorite

A stylish bedroom features a green velvet bed and a matching sofa. A large floral artwork adorns one wall beside a bright window, while light fixtures hang from the ceiling, providing illumination. The space is complemented by a patterned area rug and a bedside table.

Hotel room in Galveston

4.93 out of 5 average rating, 107 reviews

RM 3 @theolanderhotelgalveston

First of its kind in the downtown historical area of Galveston. Walk 40 yards to the best restaurants and bars where the locals go. Memory foam mattress, luxurious linens, mini fridge, microwave, snacks and hottubs with the coolest outdoor area in town. Free off road designated parking. Enjoy the glamour of this stylish, upscale place one mile from the ocean. Private bedroom and bath with secure private entrance into the 10 room botique hotel.

Superhost

A recreational area features a foosball table and a pool table. Comfortable seating is provided nearby around a large table. Soft lighting from pendant fixtures enhances the space, which is designed for relaxation and entertainment.

Hotel room in Chicago

4.82 out of 5 average rating, 114 reviews

2 Queen Bed Room

Our hotel, located conveniently close to some of Chicago's top attractions, is ideal for both business travel and vacations. Make the most of your stay with our top-notch services and on-site restaurant that offers classic American cuisine. Unwind and relax in our comfortable guest rooms with Chicago-inspired décor. Whether you are traveling alone or with family, our hotel will give you a once in a lifetime experience.

Guest favorite

The Richard I. Bong Veterans Historical Center is illuminated at night, showcasing its modern arching roof and large glass windows. The building features a combination of natural and artificial light, with signage clearly visible, creating an inviting space for visitors.

Hotel room in Superior

4.88 out of 5 average rating, 410 reviews

Superior Bay Boutique Motel Unit #5

Newly renovated boutique motel in an excellent location for exploring in the Twin Ports. Every room offers unique decor, detailed amenities and includes some of the basics for a short stay. The unit features a queen bed, a dining table and chairs, and some of the basics: Dishes, glasses, silverware, salad bowls, coffee maker, toaster, microwave, refrigerator/freezer.

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What guests are saying

The Cycle Inn #4, Two twin beds

4.5 out of 5 average rating, 8 reviews6 months ago

Amy and the stay were great! She was very helpful and offered to hold a place for us even though I made the mistake with setting the dates we were staying. We would absolutely stay here again! The location is perfect. You can walk pretty much everywhere you want to in the town. We had a great time!

Hotel room in Hermann

What guests are saying

Fink Motel 102

4.92 out of 5 average rating, 24 reviews4 months ago

There is not a lot of nightlife in Pottsboro, but the restaurants are good. It is close to Sherman/Denison and there is plenty to do there. I was glad to find I could stay there because it is close to my job. They responded quickly, gave clear instructions, it was neat, clean and spacious! I will stay there again!

Hotel room in Pottsboro

What guests are saying

Historic Dam Hotel Sunset Suite

5 out of 5 average rating, 17 reviews1 month ago

I’ve looked at staying here in the past and was finally able to book it for a long weekend during BMR. Very homey and accommodating for 8 of us to sleep comfortably. Spacious gathering area and didn’t feel like we were on top of one another. I highly recommend staying in one of Cherries hidden gems.

Hotel room in Disney