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Guesthouse vacation rentals in La Jolla, San Diego

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for La Jolla, San Diego guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
Guesthouse in San Marcos
4.96 out of 5 average rating, 315 reviews

San Marcos Private Garden Cottage

AlbertRating, 5 stars3 weeks ago
Great place and really nice backyard, great neighborhood
Top guest favorite
Guesthouse in South Park
4.84 out of 5 average rating, 126 reviews

Adorable San Diego Guesthouse

AlauraRating, 5 stars2 weeks ago
I have never stayed in South Park before. This location was so fun! Lots of little places to walk to. No issues with parking.
Top guest favorite
Guesthouse in Talmadge
4.98 out of 5 average rating, 209 reviews

Lovely Guesthouse in garden setting

RamonaRating, 5 stars5 months ago
We are so grateful to have been able to stay at Gwynn's place, it is so peaceful and lovely. Like a secret garden getaway. We loved all the small touches, and beauty of the space. Gwynn made us feel very welcome and comfortable! The pool is amazing and the outdoor spaces are delightful. Can't wait to stay here again.
Guest favorite
Guesthouse in La Mesa
4.93 out of 5 average rating, 236 reviews

Fig Tree Bungalow

LaurenRating, 5 stars4 days ago
This place was great for our quick weekend trip. Definitely worth the price.
Top guest favorite
Guesthouse in Poway
4.92 out of 5 average rating, 137 reviews

Private Family Friendly Casita/Guesthouse

KimberlyRating, 5 stars1 week ago
The casita was perfect for my family! It was bigger and even nicer in person. Robert was responsive and friendly. It was very clean, and had everything you need. We would love to stay there again!
Guest favorite
Guesthouse in Cardiff
4.95 out of 5 average rating, 105 reviews

Cozy Cottage in Encinitas Highlands

CarlieRating, 5 stars3 weeks ago
Carol and Tony provided everything we needed for a lovely family vacation- they accommodated our needs while traveling with a toddler and their guest house felt like a home away from home! Their backyard is heavenly and was the perfect place to relax in between all our outings. They are the nicest couple and I would recommend their lovely cottage to anyone looking for a peaceful retreat with easy access to all SoCal has to offer.
Guest favorite
Guesthouse in San Diego
4.93 out of 5 average rating, 190 reviews

Cosy quiet Guesthouse near SDSU

EvelynRating, 5 stars1 month ago
Guest house on a quiet street, fairly close to SDSU. It was "home base" for our stay in San Diego, while visiting family. Easy access to highways. Local stores & restaurant s nearby. Cute kitchen & patio area. Well maintained.
Guest favorite
Guesthouse in Poway
4.96 out of 5 average rating, 184 reviews

Private Family Friendly Guest House

KristenRating, 5 stars1 month ago
We had a perfectly comfortable stay and would come back again the next time we are in town if available. The backyard is amazing!

Guest house rentals with a patio

Top guest favorite
Guesthouse in North Park
5 out of 5 average rating, 18 reviews

Golden Hour Guesthouse

DanielRating, 5 stars1 month ago
We loved our stay, it was the perfect jumping off point for our adventures in San Diego
Top guest favorite
Guesthouse in Escondido
4.98 out of 5 average rating, 128 reviews

Garden Casita

CarolinaRating, 5 stars4 days ago
Pete’s Casita was the perfect weekend getaway! The home was beautiful and felt cozy. Everything was clean and the hosts were very kind!
Top guest favorite
Guesthouse in Talmadge
4.99 out of 5 average rating, 201 reviews

Adorable cottage in Talmadge

KathyRating, 5 stars2 weeks ago
Another great visit! Convenient location coupled with wonderful amenities, along with Carlos’ hospitality makes this a top choice for us when visiting San Diego to see our son!
Top guest favorite
Guesthouse in La Jolla
4.98 out of 5 average rating, 198 reviews

La Jolla Oasis: Ocean, City and Fire Works Views

HaileyRating, 5 stars3 weeks ago
1000/10 ZERO complaints! The views from the patio/front of the house are beautiful. Perfect place to go for runs/walks. My friends and I loved it! We can’t wait to come back in the summer when it’s warm. Back houses are typically not my thing but we never saw or heard anyone. Sometimes you can hear when they’re home because you can hear steps but it’s not loud. The place has everything you need: towels, extra toilet paper, utensils, cups, plates, detergent. We played music on a speaker and laughed day and night, so Sorry Atoosa if my friends and I were loud at all..
Top guest favorite
Guesthouse in La Mesa
4.99 out of 5 average rating, 257 reviews

SDCannaBnB #1 *420 *parking *dog-friendly *hot tub

DrewRating, 5 stars1 week ago
We loved our stay here! The place was very clean and so cute. Zina and Craig were so kind and checked in to make sure everything was going good. We would definitely stay here again.
Guest favorite
Guesthouse in Serra Mesa
4.95 out of 5 average rating, 100 reviews

Cozy, Quiet and Private Backyard Studio Escape

SharonRating, 5 stars1 week ago
This was the perfect Air Bnb for our honeymoon in San Diego. It was in a great area, and the location was 15 minutes from everything we wanted to do! Couldn't recommend more
Top guest favorite
Guesthouse in Point Loma Peninsula
4.95 out of 5 average rating, 58 reviews

Guest house with ocean views and private deck.

KaylaRating, 5 stars5 days ago
Cosmin’s guest house was one of the best Airbnb experiences we’ve ever had! The location was fantastic—it was close to everything we wanted to do, had easy on street parking, and was in a quiet family friendly neighborhood. The interior was extremely clean and appeared to be created with care. The kitchen was well equipped to handle all your cooking needs, and the washer/dryer were a nice addition! My family and I enjoyed our stay and felt right at home. The view from the back deck was also an added bonus! I would highly recommend.
Top guest favorite
Guesthouse in North Park
4.98 out of 5 average rating, 122 reviews

New (2022) North Park Abode w/ Roof Deck

SarahRating, 5 stars3 months ago
BOOK IT! Aesthetically well done, extremely comfortable, perfect location. Really enjoyed my stay here for 5 days. Unit has everything you may need during your stay. Love this neighborhood, so many great restaurants and shops. Parking was always available. Space is squeaky clean and bed is comfy. Next time I’m in SD I will stay here again.

Guest house rentals with a washer and dryer

Top guest favorite
Guesthouse in Carlsbad
5 out of 5 average rating, 202 reviews

Peaceful, Private, Coastal Retreat

JamesRating, 5 stars2 weeks ago
Christine's place is very thoughtfully set up. Great attention to detail and extremely responsive. The unit has a private feeling, at the end of a cul-de-sac and with a private outdoor patio space and BBQ. Bright, clean and comfortable. I am a regular Airbnb user, and its easy to tell when a host has anticipated all needs. Excellent kitchen space which I appreciated and used. Highly recommend.
Guest favorite
Guesthouse in La Jolla
4.98 out of 5 average rating, 415 reviews

Beautiful Private Villa walk to beach

SamanthaRating, 5 stars2 weeks ago
It’s was amazing staying a Kim’s guesthouse. Felt very private and peaceful. The birds sounded so beautiful in the morning, we thought it was fake at first. The flowers just outside are beautiful. The beach within walking distance was a perfect place to play, lay out, watch the sunset and surfers. We even saw dolphins one night! Just a magical time. We will definitely come back!
Guest favorite
Guesthouse in La Jolla
4.79 out of 5 average rating, 191 reviews

San Diego Shangri-La

JimRating, 5 stars3 weeks ago
This apartment is great for 2 people to enjoy the San Diego / La Jolla area. We stayed here for a full month. The apartment is very cozy and the hosts are absolutely fantastic! They have an office set up downstairs (in the garage) and work there most weekdays and occasionally on weekends, so you're not in a totally private house (you have your own entrance and space upstairs), but they are close by for questions. As is prevalent in the area our small dog was very welcome in this apartment. If you have a small dog be wary of coyotes that roam the area.
Top guest favorite
Guesthouse in Vista
4.99 out of 5 average rating, 173 reviews

Gorgeous, Quiet, Clean Guest House, Near It All

JulieRating, 5 stars2 weeks ago
You feel like you’re at a resort when staying at Zach’s. The landscaping is phenomenal, tall trees, native plants and gorgeous ornamental touches. The house was immaculate, with plenty of towels and all the things necessary to cook. The hot tub was the best way to end our day. As a super host myself, I 100% recommend Zach’s if in Vista.
Superhost
Guesthouse in Pacific Beach
4.83 out of 5 average rating, 360 reviews

Pacific Beach Guest House With Garage and A/C

BillRating, 5 stars1 month ago
Had a great stay at this Airbnb. hist provided excellent instructions and the space was accurately described in the listing. Was a great basecamp for visiting San Diego friends and exploring the city.
Top guest favorite
Guesthouse in Escondido
4.98 out of 5 average rating, 329 reviews

Private 2 bedroom apt in new craftsman ranch!

KymmberlyRating, 5 stars2 weeks ago
Decided to do a stay-cation for my best friend's birthday and Jackie's home was absolutely perfect for it. The location is amazing, the property is extremely beautiful and well maintained. We did a wine tour for my friends birthday and all the wineries we went to were just minutes from the Airbnb. The home was clean, the beds were comfortable, the front porch chairs were perfect to sit in and enjoy a glass of wine. The best part was that you feel completely safe. I personally didn't even feel the need to take the house keys when we left. We left the door unlocked which I would never normally do. I really appreciate Jackie's quick responses and also allowing us to drop off one of the cars early so we didn't have to drive multiple cars around to each winery. - if you stay I recommend cordiano winery for a sunset dinner. Thank you again, Jackie! I can't wait to be back.
Top guest favorite
Guesthouse in Carlsbad
5 out of 5 average rating, 210 reviews

Ocean/Lagoon View/New Luxury Casita /Walk To Beach

NeilRating, 5 stars1 week ago
Joe and Dee Dee were friendly, proactive and communicative hosts. The casita was replete with high end finishes, tastefully decorated and had all the amenities that we could want. It is well located within Carlsbad and we would recommend this to anyone planning a visit to the area.
Top guest favorite
Guesthouse in Mission Hills
4.97 out of 5 average rating, 246 reviews

Beautiful Historic Home and Gardens Near Downtown!

LindaRating, 5 stars1 week ago
My husband and I and our two adult children stayed in Sam's place for 6 nights. It's a delight. We walked to Balboa Park, visited the zoo, enjoyed the farmers market, hiked in Torrey Pines state park and biked in La Jolla. Every evening and morning we enjoyed Sam's home and garden-a true place to relax. Sam is a responsive and warm host. The proximity to the airport made arrival and departure a breeze. Highly recommend!

Quick stats about guesthouse rentals in La Jolla, San Diego

  • Total rentals

    50 properties

  • Total number of reviews

    9.1K reviews

  • Pet-friendly rentals

    20 properties allow pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wifi availability

    50 properties include access to wifi

  • Popular amenities

    Kitchen, Wifi, and Pool

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