House vacation rentals in St. Lucie County

Find and book unique houses on Airbnb

Top-rated house rentals in St. Lucie County

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Superhost

Home in Jensen Beach

4.85 out of 5 average rating, 104 reviews

The Driftwood Beach House on Hutchinson Island

Fun tropical home on Hutchinson Island 1/2 mile from the beach. There is also a community pool available. The house is perfect for a long weekend getaway or weeks of rest and relaxation. Escape to the colors and island breeze that only Hutchinson Island can offer. It even has a private screened in whirlpool to relax in the evening after a sun soaked boat ride or beach day. There are 3 bedrooms. One king, one queen and two full size. The home comes with internet and cable to four tvs. Paradise!

Guest favorite

The spacious great room features a high vaulted wood plank ceiling, enhancing the rustic charm. Two sofas are arranged around a unique accent table, while stylish light fixtures illuminate the area. Large windows offer a view of the outdoors, inviting natural light into the space.

Home in Port St. Lucie

4.92 out of 5 average rating, 118 reviews

Aspen of Florida luxury estate!

Experience the ultimate serenity in this luxurious vacation home. PERFECT FOR LARGE FAMILIES to fit comfortably sleeps 16. This unique 2621 square foot estate SITS ON A HALF ACRE LOT with FRUIT TREES! The backyard is fenced in with GREAT SPACE FOR KIDS & PETS TO PLAY outdoor games & activities. Prime location CLOSE TO MANY WORLD FAMOUS BEACHES & ATTRACTIONS! Just a short walk from SHOPS, RESTAURANTS, BARS & VENUES! TESLA SUPERCHARGER! & OTHER EV STATION only 4 minute drive! Turnpike 4min drive!

Guest favorite

A heated pool features a built-in hot tub, surrounded by a screened patio. The water is clear, and natural light illuminates the area. Lush greenery is visible beyond the pool, enhancing the serene outdoor setting.

Home in Port St. Lucie

4.89 out of 5 average rating, 100 reviews

Stunning Sandpiper Bay Home. Heated Pool and Spa.

Kick back and relax in this large three bedroom home with patio doors all around the gorgeous heated pool which give amazing amounts of light through the whole space. With 2 living rooms, dining room and the lovely central kitchen with open views over the whole house this space is stunning. The large master features corner bath, double vanity and a gorgeous shower. With a split plan, the remaining bedrooms share the cabana bath. Relax, Grill, Tan, Chill - Florida living at its finest. A rental

Guest favorite

Home in Port St. Lucie

4.84 out of 5 average rating, 64 reviews

Little Piece Of Heaven, on the river

River Home, with ocean access. beautiful designed with a tommy Bahama feel and coastal charm. 1,800 SQ Ft accommodates 8 comfortably. It offers a private heated pool and large 60' deck for fishing or bring your own boat. The house also offers a large car port that holds an RV, a boat or your car. Free Wi-Fi with 4 HD Smart flat screen tvs are for your entertainment. Centeraly located near Golf (PGA), beaches, restaurants and shopping. You'll truly enjoy staying in this little piece of heaven.

Top guest favorite

A spacious living area is furnished with two gray sofas and two striped armchairs arranged around a central coffee table. Natural light flows in from large sliding glass doors leading to the pool area. A soft area rug anchors the seating arrangement.

Home in Port St. Lucie

4.96 out of 5 average rating, 56 reviews

Parkes Place-Stylish Home-Heated Salt Water Pool

Our stylish short-term rental property in the heart of sunny Florida offers the perfect blend of luxury and relaxation. Dive into your private heated salt water pool surrounded by lush tropical landscaping and soak up the sun. Inside, you'll find a beautifully designed and fully equipped space, perfect for unwinding after a day of exploring all that Florida has to offer. Whether you're here for a weekend getaway or an extended stay, this is your ideal oasis for a retreat in the Sunshine State.

Top guest favorite

Home in Fort Pierce

4.96 out of 5 average rating, 51 reviews

Fort Pierce - 2BD/2BA Tropical Surfside Retreat

Experience coastal living at its finest at Surfside Beach House on Hutchinson Island. Just steps from the ocean and a beach practically all to yourself, this clean and spacious condo is one of four units, each with a private entrance set in a tropical oasis. Enjoy sun, sand, surf, hammocks, and more in what feels like home away from home. Perfectly poised for beach enthusiasts, retreats, family vacations, and reunions. Fur babies stay for FREE! For groups, inquire about renting all four units.

Guest favorite

Home in Fort Pierce

4.9 out of 5 average rating, 119 reviews

Raintree House, a Vibrant Tropical Oasis

Welcome to Raintree House, a vibrant tropical oasis on Florida's Treasure coast. This 3 bedroom, 2 bathroom treehouse style cabin features an ultra private backyard with huge pool- surrounded by mature palms. Along with 70's inspired artful decor, cedar walls, and an open floor plan, this residence is made for a relaxing getaway among friends. Whether you're beach bound, exploring trendy downtown Ft Pierce, or spending your vacation poolside, Raintree House is the perfect Floridian solace.

Superhost

A serene view of the screened pool area features a curved pool with crystal-clear water surrounded by a spacious patio. Comfortable lounge chairs and a seating area can be seen under the protective screen, offering an inviting setting for relaxation.

Home in Port St. Lucie

4.85 out of 5 average rating, 20 reviews

Sharpe House

Welcome to your paradise in our beautiful Port St. Lucie, FL. Our elegant, recently renovated, and inviting vacation rental nestled in the heart of Port Saint Lucie, Florida. This beautifully appointed, offers a perfect blend of modern comfort and coastal charm, creating an ideal home away from home for travelers seeking a memorable getaway. Enjoy our 6ft deep screen-pool and it’s privacy. Our back patio is the perfect retreat for those who really want to relax. Very close to CLOVER PARK.

Top guest favorite

A dining area features a glass table surrounded by white chairs, complemented by a wooden sideboard. A modern light fixture hangs overhead, illuminating the space. In the background, an open kitchen with an island and seating is visible, along with a cozy living room area.

Home in Port St. Lucie

4.93 out of 5 average rating, 46 reviews

The boathouse

This home is perfect for big groups or anyone looking for a roomy relaxing atmosphere. Centrally located between Miami, Orlando and Tampa, the house is only a 15 minute drive away from the beach. This is a functional and beautiful home, with a comfortable living room and open kitchen with a large Island, high ceilings, a porch and an amazing fire pit. Friends will enjoy the garage entertaining area which includes a dart board, foosball, a Piano and other games. A Pack n' Play is provided.

Guest favorite

A shaded outdoor area features a rectangular fire table surrounded by six wicker chairs. The inviting space is illuminated softly under the evening sky, adjacent to a large grassy yard enclosed by a wooden fence, creating an ideal setting for socializing.

Home in Port St. Lucie

4.95 out of 5 average rating, 20 reviews

Sandhill House - Family Friendly Beach Escape

Relax and enjoy life near the beach at this recently renovated 3 bedroom and 2 bathroom home. Enjoy over 1600 square feet, with a fully stocked kitchen, master suite, game room, shaded lenai, and a fully fenced private yard. High speed internet and 4 smart TVs are provided for your entertainment, along with books, games, and puzzles in the game room. The shaded lanai is a wonderful outdoor living space to gather around the fire table, tell stories, and have a meal.

Guest favorite

An open living area is furnished with a modern black sofa featuring vibrant orange pillows, complemented by a wooden coffee table. Natural light filters in through the large windows, revealing a spacious kitchen area in the background and a cozy seating area nearby.

Home in Port St. Lucie

4.98 out of 5 average rating, 171 reviews

Relaxing, quiet house yet close to action and fun

Great, all new relaxing getaway house. Just been remodeled and updated, fenced back yard and screened patio. Fast wifi, Four beds and two bathrooms to fit up to 8 guests comfortably, washer and dryer, BBQ grill, KEURIG, VITAMIX, and kitchen tools . Come enjoy the local non-crowded beaches or the laidback nightlife of Stuart or Jensen beach. Tradition is literally blocks away, shopping, dining, golf courses etc. Quick access to 95 and Turnpike.

Top guest favorite

A cozy living room is presented with modern decor, featuring a sectional sofa and a comfortable armchair. A large Smart TV is mounted on the wall, above a stone fireplace adorned with decorative accents. An area rug adds color to the wooden flooring, with light filtering through window treatments.

Home in Stuart

5 out of 5 average rating, 27 reviews

Luxury Escape – Heated Pool & Prime Location!

Escape to this modern farmhouse retreat in North River Shores! This beautifully remodeled 3BR/2BA home features a private heated pool, a fully stocked kitchen, and cozy indoor/outdoor living spaces. Relax in the fenced backyard, grill on the patio, or explore nearby Stuart & Jensen Beach. Perfect for families, couples, and pet owners, with top-rated amenities for a stress-free getaway. Minutes from beaches, dining, and attractions!

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What guests are saying

4Br/2Ba Home available for longer stays!

4.83 out of 5 average rating, 12 reviews8 months ago

Mariya was very responsive. We had to check into an Airbnb last minute and her place was available. Instead of having to wait 1 or 2 days for a response she responded right away and we were able to check in that same day. She was also very understanding and accommodating when we had to extend our stay. Definitely would recommend

Home in Port St. Lucie

What guests are saying

Fully-Stocked | Private Beach | Heated Plunge Pool

4.97 out of 5 average rating, 62 reviews2 weeks ago

This is our 2nd stay with Stan. We hope to return again next year. The house is perfect for us. Spacious, airy, full of light! A fully stocked kitchen, the heated pool /hot tub and the beach is just a walk across the street with a garage that has everything you need for a day in the sun. The location is quiet, peaceful, yet walking distance or a bike ride (several in the garage) to the jetty and restaurants nearby. Stan responds within minutes of reaching out to him. Looking forward to another stay!

Home in Fort Pierce

What guests are saying

The Golden Palm House

4.91 out of 5 average rating, 44 reviews1 month ago

The house was spacious, clean and had everything you needed for a comfortable stay. I was a bit surprised by the frequency of trains passing behind the house, but most were short and the noise was manageable. The view and location were fantastic for our purposes. Communication with Blair was comfortable and easy and her responses were extremely timely. She made sure we had everything we needed and seemed to genuinely care about making our stay as great as possible. I would definitely stay here again and would recommend this home to anyone staying in the Fort Pierce area.

Home in Fort Pierce

What guests are saying

Tropical Oasis w/ New Pool, Games, & Outdoor BBQ!

4.8 out of 5 average rating, 5 reviews3 months ago

Honestly this was the best Air BNB we have ever stayed at. The home was beautiful, just as described! It was extremely clean and you felt like you were right at home! The house was big, beautiful , and new! The location was amazing! The hosts were super responsive and great! We stayed 2 weeks and were there for a job (business)! We will definitely be renting this place again for a family vacation! 10 out of 10n

Home in Fort Pierce

What guests are saying

The Hub House: Heated Pool + Game Room/Peaceful

4.88 out of 5 average rating, 68 reviews1 week ago

This place was a parenting stream. We brought our kids ages range from 2 to 12 and frankly I could have left everything else at home. The house had beach toys, portable crib, white noise machine, safety measures, no unnecessary breakable knick knacks to guard against babies. There was the gorgeous pool- that I thought would make me nervous with little kids and instead the thoughtful safety measures put me completely at ease. We will NEVER book anywhere else for our yearly Vero Beach trip.

Home in Fort Pierce

What guests are saying

Beautiful Private House

4.95 out of 5 average rating, 21 reviews4 months ago

Beautiful home with lots of privacy. The home was very clean and orderly. The kitchen is large and stocked with lots of cutlery, pans and other things needed to serve large meals. We made lots of use of the well taken care of grill. The pool is also large and well maintained. Our family had a great time.

Home in Port St. Lucie