Boutique hotel vacation rentals in Southern Indiana

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in Southern Indiana

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Hotel room in Frankfort

4.82 out of 5 average rating, 11 reviews

King Room, Kitchenette

Welcome to The St. Clair Hotel in Frankfort, KY. Nestled in the heart of the modern bourbon capital, enjoy easy access to celebrated distilleries like Buffalo Trace, Woodford Reserve and more. Fully-equipped with modern amenities and a well stocked kitchenette, we're your perfect home away from home. Dine, explore and unwind in an area rich with eateries and boutiques, and be sure to visit Howser's Tavern on the first floor for a drink and a taste of local flavor. Book your memorable getaway wit

Top guest favorite

Hotel room in Newport

4.96 out of 5 average rating, 324 reviews

#1 No Cleaning/Parking Fees! Walk to Games/Music!

We are a legal "Airbnb", with a 96% Five Star Rating at 634 Monmouth St! 2 bedroom apartment, 3 blocks to Newport on the Levee, 20 minute walk to downtown Cincinnati/REDS games. Surrounded by great restaurants, nightlife, and family activities. Close to aquarium, stadiums, shopping, and music venues. You’ll love the ambiance, the outdoors space, the lively neighborhood, the people! Great for couples, kids, solo adventurers, and business! WINE BAR! KING BEDS! NO CLEANING FEE! FREE PARKING! 21 Y

Top guest favorite

Hotel room in Bardstown

4.95 out of 5 average rating, 146 reviews

Luxurious 3 Room Loft - Downtown on Court Square

The loft, a luxurious 3 room suite upstairs in the Ky Bourbon House, is steps from the Court Square in downtown. It is within walking distance to everything our town has to offer. The Loft features a Master Bedroom and Bathroom. Across the hall is the Great Room, a spacious retreat where one can relax and unwind with a Bourbon Coffee in the morning or with your favorite Bourbon Cocktail in the evening. Stay at the loft and experience "America's most Beautiful Small Town". up close!

Guest favorite

Hotel room in Leitchfield

4.95 out of 5 average rating, 39 reviews

Pistachio Mini Room @ Twin Lakes Creamery

Located near the center of Leitchfield, Twin Lakes Creamery, Grill & Inn offers updated guest rooms, each with their own private bathroom. This *small* 175ft² room features a full size pillow top mattress, refrigerator, microwave, coffee maker, and 32" TV with Hulu Live TV & Netflix. The en-suite bathroom features a walk in shower. We are in a great central location to Elizabethtown, Mammoth Cave, Rough River, & Nolin Lake. Check out our 250+ positive reviews from our other properties!

Top guest favorite

Hotel room in Metamora

4.88 out of 5 average rating, 26 reviews

Khaki Suite

Welcome to Duck Creek Farm and Inn, a charming place offering four beautiful guest rooms in the picturesque hills of Southeastern IN. Our spacious family friendly rooms are thoughtfully decorated with luxurious linens on comfy beds. Each room features pleasant views, a private bathroom, and a cozy sitting area. Unwind, relax, and rejuvenate while enjoying the comfort and hospitality we are known for at our beautiful countryside inn where you will arrive strangers but leave as friends.

Guest favorite

Hotel room in Louisville

4.89 out of 5 average rating, 103 reviews

The Olmsted Suite 101 at The Bellwether Hotel

Immerse yourself in the era of Art Deco design when you settle into the Golden Hour Suite. Working with the existing architectural features and structural elements, this room is truly an immersive experience. This space has been transformed, adding all the touches modern travelers enjoy while paying homage to the history of the building. Complete with cozy sitting area, velvet headboard, King sized organic memory foam mattress, SmartTV, coffee station, mini-fridge and microwave.

Superhost

Hotel room in Versailles

5 out of 5 average rating, 16 reviews

Rose Hill Inn Grand Library Suite

Rose Hill Inn, built in 1823, is one of the oldest estates in the city of Versailles, Kentucky. Curl up in an armchair with a book from the inn's collection in your private library. Marvel at the 12 foot windows. Enjoy your best night's rest with our hand-selected luxury bedding. With the best of the old and the new, a stay at Rose Hill Inn is sure to transport you back in time. As of August 1st, Rose Hill Inn will be offering free breakfast, included in the price of the room.

Top guest favorite

Hotel room in Prospect

5 out of 5 average rating, 9 reviews

The Nook at The Purple Martin in Louisville!

The Purple Martin is a charming boutique hotel located in the premier neighborhood of Norton Commons in Louisville, Kentucky. Known for its fine dining and exciting nightlife, Louisville offers a plethora of attractions for guests to explore and the Purple Martin is in the perfect centralized location for your stay. The rooms at The Purple Martin are elegantly furnished and decorated with all the amenities needed for a comfortable stay. Guests can relax in style and luxury!

Superhost

Hotel room in Madison

4.79 out of 5 average rating, 14 reviews

East Main Lofts - Boho 203

Welcome to Boho Loft — 203, a vibrant and whimsical retreat nestled in the heart of Madison, Indiana. This fully renovated historic building brings modern amenities to a thoughtfully designed loft. It's perfect for groups of friends, families, or two couples seeking a unique fusion of bohemian charm and modern comfort. With two king beds and an eclectic ambiance, walk to all the best shops Madison has to offer, walk along the river, or hike through Clifty Falls state park.

Superhost

Hotel room in Loveland

4.85 out of 5 average rating, 20 reviews

The Loveland Lofts - Loft 3 "Boutique Hotel"

A king suite with an open floor plan, conveniently located in a historic building that has been newly renovated into a boutique Hotel. Within walking distance of all restaurants, shops, the bike trail, and the Little Miami River guests can enjoy the energetic vibe that this town has to offer. With a total of 4 private rooms available to rent out with a communal balcony for Loft guests only, it makes a great place to reconnect with family and friends in a fun location.

Guest favorite

Hotel room in Indianapolis

4.9 out of 5 average rating, 10 reviews

Cozy River Retreat

Kick back and relax in this centrally located peaceful, warm, and stylish boutique retreat, waterfront, on White River, in the heart of Indianapolis near-to-downtown, Carmel, Fishers, Keystone-at-the Crossing, Westfield and 465 for easy access to the rest of Indy. Charming, newly renovated cottage, entire private, lower level home, with separate entrance and parking. Great amenities (W/D, patio and gazebo, river views). There is no place like this cozy retreat.