Lake house vacation rentals in Seneca

Find and book unique lake houses on Airbnb

Top-rated lake house rentals in Seneca

Guests agree: these lake houses are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Home in Starr

4.95 out of 5 average rating, 20 reviews

Lakefront, Views, Private Dock, Boat Rental, Bunks

Our beautiful, newly renovated lake front home on Lake Hartwell offers a private dock on big water, lake views, and a short walk to the private dock. With 4 bedrooms and 3 bathrooms, our lake house is set up to sleep up to 14 people. We provide kayaks for exploring the lake and exclusive rental of a 22' Bennington Tritoon stored at the boat dock for an additional daily fee of $400. (Book at adventurerentalsboat com). We are located adjacent to the old Island Point picnic area owned by the Corp

Guest favorite

Home in Martin

4.88 out of 5 average rating, 17 reviews

Clear View Cottage

Nestled in a quiet area, our charming lakehouse offers a peaceful retreat from the hustle & bustle of everyday life. Recently renovated, this beautiful home offers modern comforts while surrounded by stunning natural beauty. Breathtaking views of the lake from screened porch & deck. House is nestled in the trees, but a very short walk to the dock. Our property boasts deep water access, ideal for swimming, fishing or launching your kayak. Experience the tranquility of the lake at its fullest!!

Superhost

Home in Six Mile

4.85 out of 5 average rating, 230 reviews

House on Lake Keowee swim beach in cove w/ Dock

This two story home is located at the end of a very quiet cove with plenty of water. The beach has a fresh 6 inches of sand installed for the lake season. The walk to the lake is very short on an almost flat surface. The home will accommodate a family up to six people. The house has two floors. The main floor has a large living room with plenty of comfortable seating and satellite TV service provided. The entire main floor has hard woods along with the Master Bed Room and bed room #2.

Superhost

Home in Anderson

4.86 out of 5 average rating, 201 reviews

Lake Living with Amazing Views of Lake Hartwell

Stunning lake views in highly popular The Shoals in Portman Marina located on Lake Hartwell. Bring your pets with you, we are pet-friendly, and they'll love running around the fenced in backyard. Very large back deck overlooking the lake while you have morning coffee, grill or just relax! We also are located in a very nice, quiet neighborhood in cul de sac. Short drive to Clemson University for games or student/family events. Also, short drive to downtown Anderson and Anderson University.

Guest favorite

Home in West Union

5 out of 5 average rating, 15 reviews

New Waterfront House with Big Views & Private Dock

This new 4BR 3.5BA waterfront home has unobstructed big lake views from nearly every room. It comfortably sleeps 12 & has new furnishings throughout. There are many spaces to hang out & relax including; a sunroom, two family rooms, two open air porches and a fire pit. Lake activities include a dock with boat slip & jet ski lifts, shallow water for wading and playing, deep water for fishing and swimming. Take out the kayaks to paddle around or put out the floating mat for extra fun.

Superhost

Home in Townville

4.77 out of 5 average rating, 44 reviews

Spacious/Quiet 4BR- Lake Hartwell close to Clemson

Our Lakehouse sits on the beautiful & massive 690 miles of shoreline on Lake Hartwell in a deep water cove located in Townville, SC off Exit 11 on I85 & 5 minutes from Portman Marina & 20 minute drive to CU. This two story house sits in a very quiet residential neighborhood. Lake access is just steps from the back door to get to the dock with a smooth concrete path that has a nice gentle slope to it. The private dock is perfect for those that would like to bring their own boat. .

Guest favorite

Home in Martin

4.95 out of 5 average rating, 59 reviews

Lakeside Haven * deep water * sunset * tranquility

This spacious 3 bedroom, 2.5 bath Lake Hartwell home has everything you need for a perfect tranquil getaway. Enjoy our completely updated, tastefully decorated, clean and charming lake house with amazing water views all year round. The property is tucked in the woods and has direct access to the lake with covered, deep-water dock. Enjoy the gorgeous water views, relax on the patio, watch the sunset, experience lake life. Perfect intimate getaway far from the fast-paced city life.

Guest favorite

Home in Anderson

5 out of 5 average rating, 10 reviews

Family friendly waterfront lakehouse near Clemson

Welcome to your lakefront dream getaway on Lake Hartwell! This serene, beautifully maintained home offers comfort and style with spacious living areas and stunning lake views. Enjoy the lush, wooded backyard, expansive deck with patio furniture, and a fire pit perfect for evening s'mores. Spend your days kayaking or paddleboarding, and bring your furry friends along, as our home is dog-friendly. Just a short drive from Clemson, this retreat is ideal for relaxation and adventure.

Guest favorite

Home in Hartwell

4.93 out of 5 average rating, 120 reviews

Lake house waterfront, 10 min to downtown w Kayaks

The 'Hart' of the Lake! Quaint & cozy waterfront lake house in the heart of Lake Hartwell. Quiet and tucked away street with very few cars (lots of deer), but only 10 minutes from historic downtown Hartwell. Kayaks and floats available for use. Fire pit, gas grill, and large wrap-around deck perfect for entertaining. Enjoy the sunset on our private dock. Great for a weekend retreat at the lake or an extended stay. 200 Mbps wifi, ample parking, boat rental and boat drop nearby.

Top guest favorite

Home in Seneca

5 out of 5 average rating, 14 reviews

Casa Del Lago on Keowee- Hot Tub and Swimming

Welcome to Casa Del Lago, a charming home on Lake Keowee with Private Boat Ramp, Boat Dock, Hot Tub & More. Lake-front views in a peaceful cove on Lake Keowee. This home has a lot of features including covered boat dock, 3 private bedrooms, a large downstairs common area with bunk beds, & more. Home sleeps up to 8, including bed spaces and couches. Bring your family & friends and enjoy a getaway at the most prestigious, relaxing , and beautiful lake in South Carolina.

Guest favorite

Home in Hartwell

4.88 out of 5 average rating, 8 reviews

Hartwell Lakefront Serenity

Welcome to our serene retreat on the shores of Lake Hartwell! Nestled amidst lush greenery, this beautiful lake house offers the perfect blend of tranquility, comfort, and adventure for your next getaway. Spend your days swimming, fishing, or simply soaking up the sun from the comfort of our private double-decker dock. Whether you're seeking a peaceful vacation or an action-packed adventure, our lake house on Lake Hartwell offers the perfect setting for your next trip!

Top guest favorite

Home in Anderson

4.99 out of 5 average rating, 193 reviews

Lake Escape

This is the perfect lake house for your next family vacation, Clemson football game, or just a long weekend at the lake! Enjoy full access to Lake Hartwell with a private dock and swimming area. The house is located just 20 minutes from both Clemson and Anderson and also just 5 minutes from Portman Marina. Kayaks do not come included with the house but can be rented if inquired about ahead of time. Come enjoy some nature, relaxation, and fun at the Lake Escape!

0 of 0 items showing

What guests are saying

Gumlog Getaway Lake House • Cozy Cabin Retreat

4.86 out of 5 average rating, 14 reviews2 weeks ago

Don’t hesitate, just book it! The host was great, the place is better than the pictures and it is easy to find. I completely agree with one of the other reviews, it just feels like home when you walk in, comfortable is the best description I can give. We will be back!

Home in Lavonia

What guests are saying

Point Lot, Boat and PWC Rental

5 out of 5 average rating, 5 reviews2 weeks ago

Our stay at the lake house was great! The house was clean and had good quality beds and amazing views. The location is perfect—right on the lake and with a private dock where you can find kayaks and paddle boards. The back deck was perfect for relaxing on. We also opted to add the jet skis, which were a highlight and so much fun to zip around on! The listing was accurate, and the fire pit added a nice touch. We felt right at home, and we liked the value for a great property. Carter was easy to work with on anything and appreciate the hospitality.

Home in Seneca