
House vacation rentals in Santa Fe de Antioquia
Find and book unique houses on Airbnb
Top-rated house rentals in Santa Fe de Antioquia
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Fe de Antioquia house rentals
House rentals with a pool

Casa Río Adentro: Luxury, Nature, and Connection
Thanks to the entire property team, and Daniel the host, who was very attentive to everything. At the property we were accompanied by Darío and Delia, very friendly and attentive to everything we needed, Delia cooks delicious food, she had the house beautiful all day. We spent a few incredible days with the family. The property is beautiful, the beds are delightful, all the amenities are very good in general. 🙌🏼🙌🏼🙌🏼

Estate + Pool + Jacuzzi!
Do yourself a favor and book this place - you won’t regret it! We had an amazing time at this finca. A few things to highlight: 1. The entire property was spotless, everything was perfectly cleaned and well organized, from the linens to the kitchen supplies, all the way to the outdoor areas, you can tell a lot of thought was put into every detail 2. The entire team behind this property is excellent. Daniel y Alejandro were super responsive and Claudia and Victor were wonderful hosts. They were ready and happy to help to make our stay pleasant 3. The property is absolutely gorgeous, tastefully decorated, the pool and jacuzzi are incredible, the surroundings breathtaking, and the location is quiet and private - you will have everything and more you need to have an amazing vacation. We can’t wait to be back!

Luxury house with private pool and Jacuzzi!
The place is more beautiful than the pictures. In terms of location, it is down a steep hill, and you arrive at a flat area, but very accessible by car or motorcycle. The streets, depending on where you enter, are somewhat narrow and some have very high bumps, so if you are in low cars, check which route to take to avoid damage. The house is beautiful, impressive from the moment you enter; the decor is cozy, very complete, the barbecue is gas and there was also a barrel, so there was no need to use the charcoal I brought. The rooms are very clean, the main one overlooking the pool had a hairdryer, hair iron, clothes iron, body towels and soap for the little one. In the shower there was liquid soap but I didn't like the smell, but it did its job. The service was great from the moment we arrived. At the entrance there is a security camera that sees when you arrive and when you leave. I would definitely come back.

Santa Ana Colonial
Juan was great the cook was amazing definitely worth having they made the trip worth it.

Finca La Quinta, 10 minutes from Sopetran
The property is very nice and clean, it is very well equipped and with everything you need to have a good time with family or friends, Lisbeth's attention was excellent and she helped us with the cooking and cleaning, totally recommended the property!! 😊

Cozy Villa in the Village. Finca Palos Verdes!
estca is spectacular , the place is just as beautiful as the photos. the pool is beautiful and has lights that change color at night, it looks so cute. The Jacuzzi is super relaxing. the kitchen is very well equipped, there is everything. very comfortable rooms and cleanliness is outstanding, everything was spotless. mr. Jaime who is butordomo is very dear, and resolved our concerns , the white lady cooks very rich. there were pool towels, shower towels for each guest. In the bathrooms there was hand soap and in the shower body soap, rinse and shampoo. I go back many more times, super recommended.

Recreational house, in Sopetrán Arboreal Condominium
Excellent experience, very good location, the house was very well equipped, we didn't need anything, very good service from the host. 1000% recommended!

Beautiful country estate
Great place to stay, good amount of space for all the family and your pets
Weekly house rentals

Crystal Pool Villa 4R/5BR 10 Guest Near Medellín
Space equal to the one posted in photos, very nice and the host just like the stewardship can be a little more friendly than everything else is excellent!!!

Casa Colonial Arce y Toral - Santa Fe de Antioquia
The house is a beautiful colonial billing in the middle of town but in a quiet spot, next to great restaurants and the prettiest square. The house itself is old and full of charm, bear in mind it is an old building and it was really hot. But there were a lot of fans so I didn’t suffer in the night. Staying in such an old historical place was a great experience and the host was nice

Casa Elixir
The place is beautiful. Just like the photos, it's very clean and has towels, linens and all the necessary supplies. The only thing to consider is that Waze does not give the exact location and it was a bit difficult for us to get there. But the property as such is perfect

Beautiful house in Santafe de Antioquia
A very nice place, very quiet, we had a great time

The Dessert of the West
Only positive things about our stay at “El Dessert”. For starters, the location of the place is easy to access and close to Medellin. The place is quiet, quiet and very suitable for those who want to escape the city. David's check-in instructions were clear, he has no loss. The place is beautiful, spectacular views, silence and nature. The estate perfectly clean, the new and comfortable spaces, the bathrooms impeccable. The flexible check-in and check-out and Luz's service was very kind and attentive that we were doing well. The house has all the necessary elements to be comfortable and quiet. A very good experience, highly recommended and eager to return.

Finca Casa Blanca
Everyone is very friendly, the butler is extremely good people! The place is very nice, my family and I stayed there and we all left very satisfied. You need to have a little patience at the entrance, since some of us went by motorcycle and it's a dirt road, but with Samuel's directions, we arrived very easily and it was totally worth it 🙏🏻

Home 3 min to Santa Fe de Antioquia town
The home and location was great. The complex is beautiful with excellent common areas such as the pool. Very well kept complex, family oriented, clean and beautiful homes. The home itself was very nice and had everything we needed for our stay. However, there were a few inconveniences upon arrival and upon messaging the host we received no response. For example the key box being hidden on the side of the house and having to figure out how to get in, then the water main was shut off and having to figure out where to turn the water on. Also, the air conditioning control does not work in the main room and having to climb on the bed to manually turn on the AC. We would definitely stay here again but these are small details that were a little inconvenient and could be improved.
Private house rentals

Wonder House In San Jeronimo With Pool And Jacuzzi
We had a family weekend in this beautiful estate, everything went as expected, the butlers are very friendly and helpful.

Entire Private House in Sopetran, Antioquia.
Good location, it's just like the photos, very nice and pleasant.

Sunset Haven: Summer Bliss
Excellent accommodation and David is a very helpful host. The people in charge of the care in the home, Diana and Samuel, are very friendly and helpful. Return for a break in the accommodation or for meetings of friends and events

Casa Finca el descanso
Our stay was simply wonderful, the property is a very beautiful place, as shown in the photos, it is very well equipped, its rooms are super comfortable, the pool area and the jacuzzi are undoubtedly the best thing about this place, I would like to highlight the cleanliness and order, it is on the edge of the road, which makes it easy to access and leave anywhere, it has all the necessary amenities to share unforgettable moments and it is super safe, we are very grateful to Edison for always being attentive to every detail, for his kindness, communication was super easy, the recommendations he gave us were very valuable and above all we are very grateful for having lent us this special place, we will definitely be back !!!!

Luxury Poolside Retreat in Santa Fé
The facilities are just like the photos; the host and the butler responded instantly and were attentive to our stay all the time, highly recommended

Fantastic 4BR • Country Home/Finca en Santa Fe
We love staying at Finca Paraiso in Santa Fe. My family and I had a great time here! 🥰 Beautiful place, comfortable, specious, very convenient and close to the town center. The worker Rodrigo was amazing with his service, very attentive, friendly and welcoming. We definitely recommend this place for a fun, relaxing family time.

Vivanco House | Pool l In to Colonial Santa fe
Wonderful place, exceeds expectations, everything thought out in great detail. Highly recommended
Quick stats about house rentals in Santa Fe de Antioquia
Total rentals
70 properties
Nightly prices starting at
$10 before taxes and fees
Total number of reviews
2K reviews
Family-friendly rentals
50 properties are a good fit for families
Pet-friendly rentals
40 properties allow pets
Rentals with a pool
50 properties have a pool
Destinations to explore
- Guatapé Vacation rentals
- Envigado Vacation rentals
- Sabaneta Vacation rentals
- Santa Elena Vacation rentals
- Rionegro Vacation rentals
- Cali Vacation rentals
- Medellín Vacation rentals
- Medellin Metropolitan Area Vacation rentals
- Medellín River Vacation rentals
- Eastern Antioquia Vacation rentals
- Cartagena Vacation rentals
- Bogotá Vacation rentals
- Rentals with a washer and dryer Santa Fe de Antioquia
- Fitness-friendly rentals Santa Fe de Antioquia
- Rentals with a hot tub Santa Fe de Antioquia
- Kid-friendly rentals Santa Fe de Antioquia
- Pet-friendly rentals Santa Fe de Antioquia
- Family-friendly rentals Santa Fe de Antioquia
- Rentals with a patio Santa Fe de Antioquia
- Rentals with a sauna Santa Fe de Antioquia
- Rentals with breakfast Santa Fe de Antioquia
- Rentals with outdoor seating Santa Fe de Antioquia
- Villa rentals Santa Fe de Antioquia
- Hotel rentals Santa Fe de Antioquia
- Condo rentals Santa Fe de Antioquia
- Rentals with pools Santa Fe de Antioquia
- Apartment rentals Santa Fe de Antioquia
- Rentals with a fire pit Santa Fe de Antioquia
- Smoking-friendly rentals Santa Fe de Antioquia
- Cabin rentals Santa Fe de Antioquia
- House rentals Santa Fe de Antioquia Region
- House rentals Antioquia
- House rentals Colombia
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes