
Saint Charles vacation rentals
Book unique vacation rentals, houses, and more on Airbnb
Top-rated vacation rentals in Saint Charles
Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Saint Charles vacation rentals
Other great vacation rentals in Saint Charles

Luxury, Lakefront Chalet with Hottub and firepits
Emily's place was fantastic. She responded right away to questions I had before, during and after our stay. She even forewarned us about the roads leading to the house with the cruddy weather. The house is beautiful, just like the photos. The kitchen is fully stocked and there are plenty of towels for showers and the hot tub. Everything was clean and well cared for. Layout is perfect for larger families and groups of people looking for a quiet place to relax and have fun.

Pool + Hot Tub, Downtown, Wineries, Spacious, Cozy
My friends and I have been coming to the Brick House for years for a girls weekend. We love the location and the house has all our needs. The owners are very easy to work with and accommodating. We will be back.

Beautiful Luxury Home on water
We thoroughly enjoyed this space! The home felt very clean and comfortable. It offers several social spaces that are very welcoming and spacious. The bedrooms are also spaced well offering privacy for all of the guests. The bathrooms are beautiful with top of the line amenities. The kitchen also has everything you could need! The home is very well supplied with all the necessities too! We would love to come back!

Perfect Getaway 3BR/3BA Home
Another perfect stay at Perfect Getaway. The home was very clean and the host communication was quick and easy. Great neighborhood and great location. I highly recommend.

Cheerful one bedroom cottage on a horse farm
It was so nice to get away and relax for the night at the cottage! It was so peaceful! Water pressure in the shower was amazing and the bed was so comfortable! Will definitely stay again!

Updated Innsbrook lakefront A-Frame, ready for you
Jenny accommodated us on very short notice and was easy to work with. We enjoyed our stay and appreciated the use of the kayaks and the coziness of her place. We would stay again.

Luxury meets nature @ this Innsbrook stunning home
We picked Charlton’s home for three couples’ annual birthday trip and everything from the start of booking to check-out and in between was perfect. Charlton was a super host and always responsive if we had a question. The home was very clean, super stocked, the furnishings were pleasingly tasteful and the setting was great! Over the years we have traveled to NC, TN, AR and MI for this annual trip and while we always enjoyed our rentals and surroundings, Charlton’s home is the first one that we all said we would go back and stay again! Thanks for a great stay!

Guesthouse at Pinemark
Perfect for a wedding in town. Had plenty of room for multiple guests. Would stay here again
Quick stats about vacation rentals in Saint Charles
Total rentals
200 properties
Total number of reviews
14K reviews
Family-friendly rentals
140 properties are a good fit for families
Pet-friendly rentals
80 properties allow pets
Rentals with a pool
10 properties have a pool
Rentals with dedicated workspaces
130 properties have a dedicated workspace
Frequently Asked Questions
Are there vacation rentals with a dedicated workspace in Saint Charles?
Yes! Work meets play with ease at over 130 vacation rentals in Saint Charles featuring dedicated workspaces. Stay connected and productive in your home away from home.
How much does it cost to stay in townhouse rentals in Saint Charles?
Experience the best of Saint Charles with our townhouse rentals, starting at about $110 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Are there pet-friendly vacation rentals in Saint Charles?
Four-legged friends are welcome in Saint Charles. Choose from more than 80 vacation rentals for guests traveling with pets.
Are there Saint Charles vacation rentals on Airbnb with pools?
Yes! Dive into the perfect getaway at one of over 10 vacation homes with pools in Saint Charles, available on Airbnb. Make a splash and soak up the sun in style!
Do house rentals in Saint Charles have self check-in?
Absolutely! We offer over 40 house rentals with self check-in in Saint Charles. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Saint Charles have a bbq area?
Absolutely! We offer over 20 house rentals with a bbq area in Saint Charles. Enjoy a tailored experience with all the comforts you desire.
Do townhouse rentals in Saint Charles have wifi?
Absolutely! We offer over 10 townhouse rentals with wifi in Saint Charles. Enjoy a tailored experience with all the comforts you desire.
Are there family-friendly townhouse rentals in Saint Charles?
Saint Charles has more than 10 family-friendly townhouse rentals. Amenities on the property may include high chairs, travel cribs, or strollers.
Destinations to explore
- St. Louis Vacation rentals
- Springfield Vacation rentals
- Hermann Vacation rentals
- Innsbrook Vacation rentals
- Jefferson City Vacation rentals
- Dolomiten Vacation rentals
- Quincy Vacation rentals
- Grafton Vacation rentals
- Rolla Vacation rentals
- Ste. Genevieve Vacation rentals
- Nashville Vacation rentals
- Chicago Vacation rentals
- Rentals with outdoor seating Saint Charles
- Rentals with a fireplace Saint Charles
- Family-friendly rentals Saint Charles
- Rentals with a patio Saint Charles
- Kid-friendly rentals Saint Charles
- Rentals with a washer and dryer Saint Charles
- Rentals with a fire pit Saint Charles
- Condo rentals Saint Charles
- Pet-friendly rentals Saint Charles
- Apartment rentals Saint Charles
- House rentals Saint Charles
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Busch Stadium
- Enterprise Center
- Six Flags St. Louis
- Saint Louis Zoo
- Gateway Arch National Park
- Central West End
- Missouri Botanical Garden
- City Museum
- Hidden Valley Ski Resort
- Castlewood State Park
- St. Louis Aquarium at Union Station
- Saint Louis Science Center
- Cuivre River State Park
- Pere Marquette State Park
- Adventure Valley Zipline Tours and Paintball Park
- Raging Rivers WaterPark
- Cathedral Basilica of Saint Louis
- Grafton Winery the Vineyards
- Missouri History Museum
- St. Louis Country Club
- Boone Valley Golf Club
- The Winery at Aerie's Resort
- Bellerive Country Club
- Old Warson Country Club
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes