
Boutique hotel vacation rentals in Panama City
Find and book unique boutique hotel rentals on Airbnb
Top-rated boutique hotel rentals in Panama City
Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

Eshel Panama Suites, Atlantic suite 04
Eshel Suites, ofrece una experiencia unica para todos aquellos que deseen una estadia comoda y relajante. Diseñadas con un estilo moderno y acabados de lujo. Cada una cuenta con amplios espacios y estan decoradas con muebles de alta calidad. Los colores suaves y la iluminación cálida crean un ambiente acogedor y sofisticado. Equipadas cama queen con una marinera full, split, televisor de 43", WIFI, plancha de vapor, Caja de seguridad, miniBar, microondas, cafetera, secador y plancha de pelo.

Tropical Tranquility - Coconut Lodge
Welcome to our cozy and inviting room, perfect for relaxing or getting work done during your stay. The room is designed with a simple, yet elegant style featuring neutral tones and a refreshing green accent wall. It includes a comfortable bed and a stylish side table with a lamp for a cozy ambiance. The room is equipped with a large flat-screen TV and an efficient air conditioning system to ensure your comfort in all seasons. A small desk, making it an ideal for work or study.

The City Suite #208 | La Résidence Panamá
Contemporary comfort, for the modern traveler. This 43-50m² suite features 2 full beds + sofa bed, full kitchen, washer/dryer, Coffe machine, and A/C — everything you need to feel at home. At LA RÉSIDENCE, we offer more than just a stay — we deliver a complete experience. With our blend of modern design, central location, and thoughtful amenities, we provide a space designed for your convenience and productivity.

Jr. Suite Rm #3 - Cerro Azul
La Semilla Ecolodge is a Boutique Hotel integrated in to the natural space of Chagres National Park. It is located 1 hour from downtown Panama City, and features a restaurant/bar, jacuzzis, billards and games, Turkish bath and botanical garden. Our Jr Suite is fully equipped for a eco-escape into the cloud forest of Cerro Azul. Take advantage of hiking, kayaking, or whatever your interest in this tranquil setting.

Private rooms Sofia's B&B Hostal Boutique
Boutique hostel-style accommodation, we have 7 comfortable private rooms with bathroom, for a total capacity of 18 guests. The rate shown by Airbnb for your reservation is for 2 guests per room, i.e., guests will need to share beds and/or rooms. If you require a special room layout for your group, please contact the host first, as the rate may vary.

Corcho rooms #2 - king room with balconies
Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.

Hotel san Roque
Excellent location, one block from the metro station, next to habanos cafe, and restaurants of Lebanese, Colombian, Panamanian, Panamanian, bars and nightlife on the same street of major hotels such as the Euro star, Marriott, continental among others... safe and privileged location among others... safe and privileged location

Suite Room in the ORHO Hotel
excellent mini apartment with the best view of the most famous building in Panama F&F Tower in the heart of the Panamà city. For information such as: transportation, transfers, tours, location, places of interest, itinerary, please consult first, since we have completely reliable, safe and economical transportation services.

Entire place Sofia's B&B Hostal Boutique
Boutique hostel accommodation, we have 7 comfortable private rooms with bathroom, for a total capacity of 18 guests. You can make use of the well equipped kitchen, comfortable living room and dining room. We have a washer and dryer at your disposal at an extra cost.

The Corner Suite #110 | La Résidence Panamá
Contemporary comfort for the modern traveler. This 35–37 m² suite features a king-size bed, full kitchen, washer/dryer, Coffe machine, and A/C — designed with thoughtful touches to make you feel at home.

Beautiful loft #5 - kingsize bed
Enjoy charming "Corcho rooms" in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs.

Beautiful loft #6 - king size and single bed
Enjoy charming "Corcho rooms" in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs.
Popular amenities for Panama City boutique hotel rentals
Family-friendly boutique hotels rentals

Charming Hotel in Casco Viejo Santa Ana Deluxe

Private rooms Sofia's B&B Hostal Boutique

The City Suite #208 | La Résidence Panamá

Beautiful loft #5 - kingsize bed

The Corner Suite #110 | La Résidence Panamá

Eshel Panama Suites, Atlantic suite 04

Pool side, Family suite, two bedroom one bath.

Entire place Sofia's B&B Hostal Boutique
Boutique hotels rentals with a patio
Other boutique hotel vacation rentals

Charming Hotel in Casco Viejo Santa Ana Deluxe

Private rooms Sofia's B&B Hostal Boutique

The City Suite #208 | La Résidence Panamá

Beautiful loft #5 - kingsize bed

The Corner Suite #110 | La Résidence Panamá

Eshel Panama Suites, Atlantic suite 04

Pool side, Family suite, two bedroom one bath.

Entire place Sofia's B&B Hostal Boutique
Quick stats about boutique hotel rentals in Panama City
Total rentals
30 properties
Nightly prices starting at
$30 before taxes and fees
Total number of reviews
370 reviews
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wifi availability
30 properties include access to wifi
Popular amenities
Kitchen, Wifi, and Pool
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