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Serviced apartment vacation rentals in Panama City

Find and book unique serviced apartment rentals on Airbnb

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Popular amenities for Panama City serviced apartment rentals

Family-friendly serviced apartment rentals

Guest favorite

Apartment in El Cangrejo

4.9 out of 5 average rating, 51 reviews

ElCangrejo 2BR - Parks & Bars Nearby !

EricRating, 5 stars2 months ago
Very nice area - put me within a 20 min walking radius of everything I needed.

Hotel room in San Felipe

4.9 out of 5 average rating, 40 reviews

Apart-hotel Boutique- Heart of the old city

TomasRating, 5 stars38 months ago
Absolutely amazing. Place was spaciouse, clean, well equipped. Location was right in the heart of Caso Viejo and Andres was a true gentlemen our whole stay there. I would highly recommend this place to anyone looking to stay in the heart of Casco Viejo. Dining, entertainment, sight seeing walking all walking distance. truly 5 out of 5 review.

Hotel room in San Felipe

4.9 out of 5 average rating, 48 reviews

Beautiful Boutique Apart-hotel view & services

LeeRating, 5 stars22 months ago
Wonderful Airbnb in Casco. La Isabella Suites was located in the heart of CV. Apartment was very spacious and comfortable. A balcony overlooked a beautiful park. Great stay. Highly recommended!

Hotel room in San Felipe

5 out of 5 average rating, 33 reviews

Heart of the Old Town: Unique Boutique ApartHotel

ChelseaRating, 5 stars11 months ago
This place is gorgeous and has all the amenities. We wish we could have stayed longer. we arrived with a car and had prepaid to park in their small ramp. We thought the car would have GPS but it didn't so we realized we needed SIM cards to get around the country. Rodrigo checked us in and it was five star service from the start. He then walked us to shops until we found and purchased a SIM for our phones. The instructions were in Spanish so he then helped us set up the SIM cards. He did an informal walking tour and showed us some recommended restaurants so we could have dinner. The location is awesome and surrounded by great restaurants and shops in the heart of Casco Viejo. The rooms are gorgeous and the balcony's are fantastic for watching the bustling town. We couldn't recommend this place more!

Hotel room in San Felipe

4.92 out of 5 average rating, 48 reviews

Beautiful boutique Apart-hotel-views and service

BrendaRating, 5 stars25 months ago
A beautiful high-ceilinged suite with all the amenities. Architecturally interesting with classic modern furniture combined with colonial-sized space. Very accommodating host who suggested a series of restaurants nearby. Just a little snag checking in.

Hotel room in San Felipe

4.89 out of 5 average rating, 38 reviews

Boutique apart-hotel- Heart Old City

AndreaRating, 5 stars20 months ago
isabella Suites is a lovely apartment, comfortable and very well situated. Andres and all the staff were friendly and very helpful. My family and I really enjoyed our stay at Isabella Suites and the Casco Antiguo of Ciudad de Panama.

Hotel room in San Felipe

4.95 out of 5 average rating, 43 reviews

Boutique apart-hotel - Old town center

AndrewRating, 5 stars34 months ago
Andres is an amazing host! He was super responsive, very helpful and was extremely easy to communicate and coordinate with. The apartment was exactly as pictured and the location was very close to all the best restaurants and bars. I would definitely come back and stay here again and recommend it for anyone visiting Casco Viejo in Panama City!

Apartment in Panamá

4.69 out of 5 average rating, 26 reviews

Best place in Panama @ Yoo 50 floor

Al Rating, 5 stars1 month ago
Excellent stay from start to finish! Felt right at home! Great communication as well! Amenities are far more than listed actually! Book it

Serviced apartment rentals with a washer and dryer

Guest favorite

Apartment in Panamá

4.92 out of 5 average rating, 24 reviews

New studio apartment in front of the sea

CindyRating, 5 stars2 days ago
GREAT stay!! Easy to get around with Uber who were all familiar with the entry location, and great walking in the area too. Very comfortable apartment with two full bathrooms, and full kitchen, and super clean (the building as well). AWESOME view! Great rooftop restaurant upstairs. Communication with Blanca was always prompt, courteous, and helpful. I would definitely stay here again!
Guest favorite

Apartment in Panamá

4.94 out of 5 average rating, 17 reviews

Full Apartment + WiFi + 5G+Pool in Panama & Family

AncizarRating, 5 stars4 weeks ago
Beautiful place - great views 🤩 Definitely recommend

Apartment in El Cangrejo

4.67 out of 5 average rating, 3 reviews

5 Star Apt+AC+WiFi+Pool+Gym+Good Location @Panama

DavidRating, 5 stars3 weeks ago
This is a really great apartment for the money. Comfortable, quiet and good accomodations. I think for 1-2 people, this is apartment would be very comfortable. It had everything you need in the kitchen and other areas of the unit. I would recommend and will rent again if I return to Panama and it's available.
Guest favorite

Apartment in Punta Pacifica

4.9 out of 5 average rating, 71 reviews

The best location in Panama

DennisRating, 5 stars1 week ago
Everything was awesome
Guest favorite

Apartment in Panamá

4.9 out of 5 average rating, 39 reviews

Spacious and beautiful apartment in front of the bay.

ChrisRating, 5 stars2 weeks ago
I couldn't have picked a better place to stay visiting Panama City for my first trip to Panama. Leidy's place was beautiful. The decor and furniture was beautiful and comfortable. The seaside view was breathtaking looking out over the water and city. The pool was first class. I highly recommend staying here and I will definitely book her place every time I visit!

Apartment in Panamá

4.66 out of 5 average rating, 32 reviews

Modern Luxury Apartment in Condado Del Rey

MarielaRating, 5 stars1 month ago
The apartment is located in a good area in Condado del Rey, perfect for our family!
Guest favorite

Apartment in Panama City

4.9 out of 5 average rating, 72 reviews

Bright and spacious 1BR Apt @CascoViejo w/terrace

AbhinavRating, 5 stars1 week ago
Amazing location and a beautiful apartment with lots of space. Very neatly kept. Highly recommend for both solo and group travelers. I'd visit again!
Guest favorite

Apartment in Panamá Viejo

4.71 out of 5 average rating, 7 reviews

Luxury 18th View Coco Suite of the Panama Sea

AishaRating, 5 stars1 week ago
This location was in a prime area. walking distance to several local places. Restaurants, grocery, pharmacy, bars and clubs were within a 2 mile radius of the residence. Breathtaking views of Panama from the balcony and amazing sun rises from every room of the apartment. Pictures were exact and even when we needed new batteries we were accommodated within a few hours. the host was attentive and responsive duduring our stay. The personalized welcome was also great. I will definitely come back to this location again.

Monthly serviced apartment rentals

Apartment in Cuidad de Panama

4.78 out of 5 average rating, 50 reviews

Super Offer Cozy Apartment (Long-Term)

MarianelaRating, 5 stars30 months ago
Sofia is the best host, I just have to thank her for making me feel at home these almost 6 months, and the apartment super nice and comfortable, 100% recommended.
Guest favorite

Private room in Panamá

4.87 out of 5 average rating, 53 reviews

Spacious, comfortable with beautiful view for executives.

GeorgeRating, 5 stars1 month ago
Mariela was such a great host, she helped me alot, always with a smile 😃, She also helped me with Uber, markets, eye glass repair, you name it. In Bocas del Toro now, but can't wait to go back.

Private room in Marbella

4.64 out of 5 average rating, 14 reviews

Save $$$ Panamas Best Studio: Cadillac Location!

FaroukRating, 5 stars13 months ago
Great place will stay again

Private room in Panamá

4.81 out of 5 average rating, 21 reviews

Private room in Panama City

XiomaraRating, 5 stars4 months ago
Cynthia was very kind, the accommodation was very clean and in a great location, her mom was a love with us, super recommended, she would come back without hesitation
Guest favorite

Private room in El Cangrejo

5 out of 5 average rating, 8 reviews

Comfortable room private bathroom, only women.

JacquelynRating, 5 stars1 month ago
Carolina was a great host. Very attentive to my needs even though there was a language barrier. Google translate was definitely my friend. Her place is located in an area where you can walk to pretty much everything and Ubers are affordable if needed. Overall, great stay.

Apartment in Panamá

4.54 out of 5 average rating, 13 reviews

Apartamentos-Brisas del Mirador - Panamá Campestre

GilRating, 5 stars4 months ago
Great, around the area to go by car, many trails and activities can be done. Comfortable and ideal place.

Private room in Panamá

4.93 out of 5 average rating, 14 reviews

Private room in luxurious building

RodrigoRating, 5 stars34 months ago
Everything was excellent! The apartment is located in a good neighborhood of Panama, pretty close of restaurants, pubs, gym clubs, etc… the hosts were really kind.. I truly recommend it

Quick stats about serviced apartment rentals in Panama City

  • Total rentals

    220 properties

  • Nightly prices starting at

    $10 before taxes and fees

  • Total number of reviews

    5.3K reviews

  • Family-friendly rentals

    80 properties are a good fit for families

  • Pet-friendly rentals

    80 properties allow pets

  • Rentals with a pool

    150 properties have a pool

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