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Serviced apartment vacation rentals in Panama City

Find and book unique serviced apartment rentals on Airbnb

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Popular amenities for Panama City serviced apartment rentals

Family-friendly serviced apartment rentals

Guest favorite

Apartment in El Cangrejo

4.9 out of 5 average rating, 52 reviews

ElCangrejo 2BR - Parks & Bars Nearby !

JeffRating, 5 stars1 week ago
I stayed for 5 weeks and would of stayed longer if it wasn’t rented

Hotel room in San Felipe

4.9 out of 5 average rating, 40 reviews

Apart-hotel Boutique- Heart of the old city

TomasRating, 5 stars39 months ago
Absolutely amazing. Place was spaciouse, clean, well equipped. Location was right in the heart of Caso Viejo and Andres was a true gentlemen our whole stay there. I would highly recommend this place to anyone looking to stay in the heart of Casco Viejo. Dining, entertainment, sight seeing walking all walking distance. truly 5 out of 5 review.

Hotel room in San Felipe

4.9 out of 5 average rating, 48 reviews

Beautiful Boutique Apart-hotel view & services

LeeRating, 5 stars23 months ago
Wonderful Airbnb in Casco. La Isabella Suites was located in the heart of CV. Apartment was very spacious and comfortable. A balcony overlooked a beautiful park. Great stay. Highly recommended!

Hotel room in San Felipe

5 out of 5 average rating, 33 reviews

Heart of the Old Town: Unique Boutique ApartHotel

ChelseaRating, 5 stars12 months ago
This place is gorgeous and has all the amenities. We wish we could have stayed longer. we arrived with a car and had prepaid to park in their small ramp. We thought the car would have GPS but it didn't so we realized we needed SIM cards to get around the country. Rodrigo checked us in and it was five star service from the start. He then walked us to shops until we found and purchased a SIM for our phones. The instructions were in Spanish so he then helped us set up the SIM cards. He did an informal walking tour and showed us some recommended restaurants so we could have dinner. The location is awesome and surrounded by great restaurants and shops in the heart of Casco Viejo. The rooms are gorgeous and the balcony's are fantastic for watching the bustling town. We couldn't recommend this place more!

Hotel room in San Felipe

4.92 out of 5 average rating, 49 reviews

Beautiful boutique Apart-hotel-views and service

JeffRating, 5 stars24 months ago
The place was gorgeous and the staff was super friendly, helpful, and attentive. The location couldn't be any better for exploring Casco Viejo.

Hotel room in San Felipe

4.89 out of 5 average rating, 38 reviews

Boutique apart-hotel- Heart Old City

AndreaRating, 5 stars21 months ago
isabella Suites is a lovely apartment, comfortable and very well situated. Andres and all the staff were friendly and very helpful. My family and I really enjoyed our stay at Isabella Suites and the Casco Antiguo of Ciudad de Panama.

Hotel room in San Felipe

4.95 out of 5 average rating, 43 reviews

Boutique apart-hotel - Old town center

AndrewRating, 5 stars35 months ago
Andres is an amazing host! He was super responsive, very helpful and was extremely easy to communicate and coordinate with. The apartment was exactly as pictured and the location was very close to all the best restaurants and bars. I would definitely come back and stay here again and recommend it for anyone visiting Casco Viejo in Panama City!

Apartment in Panamá

4.7 out of 5 average rating, 27 reviews

Best place in Panama @ Yoo 50 floor

MarioRating, 5 stars1 month ago
Nice Condo On Avenida Balboa and cinta costera.Beautiful building.Close to all the best restaurants ,bars and attractions,The host, Mr A, Did a good job giving is instructions.We will stay there again.Thank you A .

Serviced apartment rentals with a washer and dryer

Guest favorite

Apartment in Panamá

4.92 out of 5 average rating, 25 reviews

New studio apartment in front of the sea

CindyRating, 5 stars1 month ago
GREAT stay!! Easy to get around with Uber who were all familiar with the entry location, and great walking in the area too. Very comfortable apartment with two full bathrooms, and full kitchen, and super clean (the building as well). AWESOME view! Great rooftop restaurant upstairs. Communication with Blanca was always prompt, courteous, and helpful. I would definitely stay here again!

Apartment in El Cangrejo

4.67 out of 5 average rating, 3 reviews

5 Star Apt+AC+WiFi+Pool+Gym+Good Location @Panama

DavidRating, 5 stars1 month ago
This is a really great apartment for the money. Comfortable, quiet and good accomodations. I think for 1-2 people, this is apartment would be very comfortable. It had everything you need in the kitchen and other areas of the unit. I would recommend and will rent again if I return to Panama and it's available.

Apartment in Panamá

4.5 out of 5 average rating, 8 reviews

Casa Mariposa Serviced Apartment D, Clayton Ancon

ChristianRating, 5 stars7 months ago
Perfect place, fit all eight of us without it feeling too crowded. Having a laundry and dryer set as well as hot water was excellent🙌

Apartment in Punta Pacifica

4.89 out of 5 average rating, 73 reviews

The best location in Panama

TanyaRating, 5 stars2 weeks ago
Giara should be recognized as a SuperHost. She was so respond and took every measure to make my stay wonderful. Thank You, Giara!

Apartment in Panamá

5 out of 5 average rating, 3 reviews

Apartamento completo Panama City

DylanRating, 5 stars3 months ago
Susan's apartment is super nice maybe the best AirBnb in Panama, thank you so much for everything Susan!!

Apartment in Panamá

4.71 out of 5 average rating, 45 reviews

Cozy apartment in Panama

AldoRating, 5 stars1 week ago
excellent accommodation in a nice and quiet area, like about 10km from the old town, easy to mobilize by vehicle. comfortable and air-conditioned rooms. Jorge was very attentive to hand over the place to us. I would definitely come back
Guest favorite

Apartment in Panama City

4.91 out of 5 average rating, 81 reviews

Bright and spacious 1BR Apt @CascoViejo w/terrace

CynthiaRating, 5 stars1 day ago
We have stayed with this group several times and each has been better than the last. This place is HUGE and the open space was absolutely amazing. We were amply rewarded for the stair we climbed if o lender the rooftop alone. Appliances were lovely and we were comfortable during our stay. MAURICIO IS A DREAM to work with. We will be back again.
Guest favorite

Apartment in Marbella

4.98 out of 5 average rating, 57 reviews

Panama Canal City Luxury Condo ocean view balcony

AndrewRating, 5 stars1 month ago
We picked this AirBNB because of the positive reviews. . .and were glad we did so. The apartment was exactly as advertised. The location was great--there's a grocery store just around the corner and numerous restaurants within walking distance.

Monthly serviced apartment rentals

Apartment in Cuidad de Panama

4.78 out of 5 average rating, 50 reviews

Super Offer Cozy Apartment (Long-Term)

MarianelaRating, 5 stars31 months ago
Sofia is the best host, I just have to thank her for making me feel at home these almost 6 months, and the apartment super nice and comfortable, 100% recommended.
Guest favorite

Private room in Panamá

4.87 out of 5 average rating, 54 reviews

Spacious, comfortable with beautiful view for executives.

AllyssaRating, 5 stars2 weeks ago
Mariela was a great host, always kind and helpful. Amazing response times and recommended places to see and/or eat. She's lovely and I highly recommend 👌🏽

Private room in Marbella

4.64 out of 5 average rating, 14 reviews

Save $$$ Panamas Best Studio: Cadillac Location!

FaroukRating, 5 stars14 months ago
Great place will stay again
Guest favorite

Private room in El Cangrejo

5 out of 5 average rating, 8 reviews

Comfortable room private bathroom, only women.

JacquelynRating, 5 stars3 months ago
Carolina was a great host. Very attentive to my needs even though there was a language barrier. Google translate was definitely my friend. Her place is located in an area where you can walk to pretty much everything and Ubers are affordable if needed. Overall, great stay.

Apartment in Panamá

4.54 out of 5 average rating, 13 reviews

Apartamentos-Brisas del Mirador - Panamá Campestre

GilRating, 5 stars5 months ago
Great, around the area to go by car, many trails and activities can be done. Comfortable and ideal place.

Private room in Panamá

4.93 out of 5 average rating, 14 reviews

Private room in luxurious building

RodrigoRating, 5 stars35 months ago
Everything was excellent! The apartment is located in a good neighborhood of Panama, pretty close of restaurants, pubs, gym clubs, etc… the hosts were really kind.. I truly recommend it

Quick stats about serviced apartment rentals in Panama City

  • Total rentals

    230 properties

  • Nightly prices starting at

    $10 before taxes and fees

  • Total number of reviews

    6K reviews

  • Family-friendly rentals

    90 properties are a good fit for families

  • Pet-friendly rentals

    90 properties allow pets

  • Rentals with a pool

    160 properties have a pool

Destinations to explore