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Guesthouse vacation rentals in Orange County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Orange County guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
Guesthouse in Apex
4.93 out of 5 average rating, 385 reviews

Country place close to all Triangle locations

TriciaRating, 5 stars2 weeks ago
So thankful I found this gem 💎 for my stay in North Carolina. When I checked in Nancy & her husband were outside and they were both very sweet and helpful with check-in. When we were settled, they had no problems introducing us to their horses & chickens as a city girl I was so excited lol overall great stay, they’re friendly people with a beautiful suite in a very quite neighborhood.I would definitely stay again 😊
Guesthouse in Chapel Hill
5 out of 5 average rating, 4 reviews

Chapel Hill Airstream Hotel

StacieRating, 5 stars11 months ago
Definitely glamping We had a lovely visit Very nice people and A lovely airstream. A fun adventure
Top guest favorite
Guesthouse in Cary
4.93 out of 5 average rating, 340 reviews

Central to Everything, Renovated, Dog Friendly.

ElliottRating, 5 stars2 weeks ago
Thank you so much for welcoming us into your lovely home. It was a very comfortable stay for the pup as well as myself!! I’ll be sure to keep you in mind for future travels. Marianne was a wonderful hostess!!
Guest favorite
Guesthouse in Rougemont
4.9 out of 5 average rating, 205 reviews

Cozy Cottage on a Hilltop

LioninaRating, 5 stars1 week ago
My stay was very pleasant. I was too busy to enjoy everything as I was buying a house for myself. The only thing I regret that I missed super interesting talks with Mary. She is an amazing human being! Thank you!
Top guest favorite
Guesthouse in Chapel Hill
4.96 out of 5 average rating, 378 reviews

Cozy Secluded Accessible West Wing

JoshRating, 5 stars2 weeks ago
This place is great! Close drive to Chapel Hill + surrounding area. Once you get to the house it feels like a totally different world.
Guesthouse in Carrboro
4.96 out of 5 average rating, 71 reviews

Seomra Guestsuite in Carrboro

LaurelRating, 5 stars2 weeks ago
We loved staying at Seomra Guestsuite. Very comfortable, clean, attractive, great snacks! Aja is very friendly and helpful. This was one of our best airbnb experiences. Am recommending it to local friends who might need accommodation for visitors.
Guest favorite
Guesthouse in Saxapahaw
4.92 out of 5 average rating, 761 reviews

The Yurt at Frog Pond Farm

AdamRating, 5 stars6 days ago
Really peaceful spot surrounded by nature—great place to relax. Loved the hot tub and the nature art walk. Linda and Steven were super friendly and helpful. Would definitely recommend!
Top guest favorite
Guesthouse in Durham
4.99 out of 5 average rating, 259 reviews

LaCasita, charming 2-story guest house near Duke

BrynnRating, 5 stars2 weeks ago
Sally was a wonderful host. She went out of her way to give us coffee and make us feel comfortable. Amazing experience. I highly recommend staying at this peaceful & beautiful spot!

Guest house rentals with a patio

Top guest favorite
Guesthouse in Holly Springs
5 out of 5 average rating, 121 reviews

"Wit's End" welcomes you! 2BR comfy guest house

WolfRating, 5 stars4 weeks ago
Wish I could give it 10 stars. The accommodation was very clean, super comfortable and in a beautiful and quiet location. It’s easy to access independently. She should be granted beyond super host status. She is very accommodating and helped us in many ways. We are truly appreciative of you Jennifer.
Top guest favorite
Guesthouse in Chapel Hill
5 out of 5 average rating, 81 reviews

Carolina Cottage

MarthaRating, 5 stars1 week ago
We booked Kirsten’s cottage for a weekend reunion in Chapel Hill with some of my dearest friends. There was ample room and amenities that made it easy for everyone to be comfortable and reconnect. Kirsten was a fabulous host that made checking in/checking out a breeze and made sure we had everything we needed to make this weekend possible. I would a hundred times over book her again (and most likely will!) anytime my friends and I are looking for a getaway back home. Go Heels and go Kirsten!
Top guest favorite
Guesthouse in Durham
5 out of 5 average rating, 24 reviews

“Meelie Doll”~ Private - Cozy Stdio Apt abv garage

JoseRating, 5 stars2 weeks ago
this place was super homey. Camille went above and beyond by providing all the basic essentials. she had signs around the house that were super helpful. all around very welcoming and the perfect spot for out stay. I'm looking forward to staying here again the next time I'm in the area
Guest favorite
Guesthouse in Durham
5 out of 5 average rating, 16 reviews

Guesthouse in the heart of South Durham

DebRating, 5 stars6 days ago
Lovely light filled space in a peaceful wooded setting. As a retired chef, I really appreciated the well equipped kitchen with full sized appliances. Looking forward to staying here again!
Top guest favorite
Guesthouse in Durham
4.98 out of 5 average rating, 116 reviews

Gordon Guesthouse Studio Suite w/ hot tub & pool!

EmilyRating, 5 stars2 weeks ago
Angela & Bobby were so welcoming and helpful throughout our stay! The Airbnb itself was secluded and the perfect mix of feeling like you’re out in the woods but also close enough to things you may need! The hot tub was awesome and they did a wonderful job of keeping the grounds clean despite the environment working against them! Their list of recommendations was perfect! We would love to come back another time and explore Durham and Raleigh some more! They are in the perfect location to travel to either place!
Guest favorite
Guesthouse in Raleigh
5 out of 5 average rating, 42 reviews

Light & Bright Starlit Loft walking to Lenovo Cntr

KaleshaRating, 5 stars2 weeks ago
Ryan’s place was exactly as advertised! N surprisingly very private and quiet even though it’s the guest house above a garage. Ryan himself was very responsive. He graciously allowed us to park and sit our bags down early so we could make it to our event. N he gave us an uber driver recommendation, who was also great!
Superhost
Guesthouse in Durham
4.85 out of 5 average rating, 34 reviews

Boarding House

SaraRating, 5 stars2 weeks ago
Beautiful spot! So clean and tidy, and the shower was really amazing! Spacious and beautiful. It would have been nice to have a few things like side tables and lamps in the bedroom, mat at door, more kitchen utensils, etc. But overall excellent price for such a beautiful little home. Quiet and peaceful!! Washer and dryer also available, which is a great bonus for anyone staying extended amount of time.
Top guest favorite
Guesthouse in Durham
5 out of 5 average rating, 36 reviews

New Apt- walk to everything Rockwood

DyaniRating, 5 stars2 weeks ago
The guesthouse was beautiful. The pictures did not do it justice. The space is very roomy, high ceilings, beautiful natural lighting, and the air conditioning was efficient. The bed was also surprisingly very comfortable. I would definitely recommend.

Guest house rentals with a washer and dryer

Top guest favorite
Guesthouse in Cary
5 out of 5 average rating, 141 reviews

Guest House on the Cary Downtown Park!

JohnRating, 5 stars3 weeks ago
My review speaks well of this rental. I wouldn't hesitate to refer or to stay here again. Having said that there are a few things I think could be addressed and one thing that may concern others. First the temps inside the unit rose to over 80 degrees making sleeping a bit uncomfortable. I attempted to put on the AC with no avail. While there are ceiling fans, which do help, the one in the living room makes considerable noise and we couldn't use it. The alleyway that leads to the unit is a loose gravel cartway with rutts. Daytime walking is not too bad however it can be dicey after dark. It is also a dark isolated cartway that I would not feel safe having my wife or others used alone. I think that the property owner doesn't give an accurate description of where this unit is located and how to access it. While the main house is in front of this unit on a main street the tenant has to walk completely around the block traversing this gravel alleyway to get to the street.
Top guest favorite
Guesthouse in Pittsboro
4.98 out of 5 average rating, 46 reviews

The Sacred Cedar

LizRating, 5 stars3 weeks ago
I can’t rave about the Sacred Cedar enough. Beautiful spot, impeccably decorated with plenty of room, a glorious bathtub, a wonderful library, and fantastic hosts. Joyce and Vance made last-minute accommodations for me and were so lovely and helpful. I will absolutely be back!
Guest favorite
Guesthouse in Durham
4.93 out of 5 average rating, 90 reviews

Duplex filled with natural light

WilliamRating, 5 stars1 week ago
This is a nice, clean spot from which to explore Durham, whether downtown, Duke campus, or the Trinity Park neighborhood in which it is situated. Recommended.
Top guest favorite
Guesthouse in Apex
4.99 out of 5 average rating, 173 reviews

Tilly Guest House - Downtown Apex

PeterRating, 5 stars1 month ago
My wife and I came for the Tobacco Road Marathon. Joel and Shelli's place was perfect for us. They were friendly and welcoming hosts. Their place is one most comfortable well-equipped and attractive AirBnBs that we've stayed in. Would love to stay here again next time! Thank you!
Guest favorite
Guesthouse in Apex
4.94 out of 5 average rating, 18 reviews

Private 'Barn'dominium with No Cleaning Fee!

RobinRating, 5 stars1 week ago
Mark was an excellent host. He was available at all times with a smile and friendly word. I highly recommend this studio apartment. The location was perfect, and right near downtown Apex.
Guest favorite
Guesthouse in Durham
4.91 out of 5 average rating, 11 reviews

Bullish on Carolina

AbbyRating, 5 stars3 weeks ago
Great spot nestled right near Duke’s East Campus. We didn’t have a car, and we were able to access lots of great restaurants and get around easily without one. The Airbnb was also spotless, and in a super quiet area of town. Will definitely be telling our friends about this spot if they are visiting Duke and the surrounding areas!
Guest favorite
Guesthouse in Chapel Hill
4.96 out of 5 average rating, 134 reviews

Treehouse in the Woods

CatherineRating, 5 stars3 weeks ago
Josh's place suited me perfectly.The kitchen was well equipped as I needed to cook my meals to take to a retreat I was doing. The woods are beautiful, Josh was very helpful and quickly responsive. If you want peace and quiet yet a short drive from all the amenities of town, stay here!
Top guest favorite
Guesthouse in Blanch
5 out of 5 average rating, 32 reviews

Backwoods Guesthouse Near VIR

ElizabethRating, 5 stars2 weeks ago
I look at this as my home away from home. I always enjoy my stay.

Destinations to explore