
Lake house vacation rentals in Lake Moultrie
Find and book unique lake houses on Airbnb
Top-rated lake house rentals in Lake Moultrie
Guests agree: these lake houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Lake Moultrie lake house rentals
Waterfront lakehouse rentals

Lovin’ Lake Life

Riverhouse Retreat on the Edisto River

Lake House on the Water with Boat Ramp!

Santee lakefront home, big water right off I-95

Beautiful renovated home in the Charleston area

Lake Living

Cozy 3 bed 2 bath on the waterfront

Million dollar view, close to everything. Kayaking
Pet-friendly lake house rentals

Beautiful and spacious 5/3, near I95 /I 26.highway

Shady Cove on Fountain Lake

A Lake Slice of Heaven

Hideaway on Lake front for 7 guests

Cozy 3 bed 2 bath waterfront lake house

Cutest Cottage on the Lake

No Wake Zone-Edisto River-*Dock&Boat Landing*

Lake House Retreat - Pet Friendly - Private Dock
Private lake house rentals

The Fishnet

Santee/Lizzie's Creek Lakefront

Paradise on Lake Marion

Fisherman’s stay! Lake Getaway!

Charleston-themed House for 10!

Lake Side Retreat

SANTEE LAKE MARION GOAT ISLAND AREA NEWLY UPDATED

Manning Majesty - Main house and Cottage
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- Sullivan's Island Beach
- White Point Garden
- Middleton Place
- Hampton Park
- The Charleston Museum
- Waterfront Park
- Angel Oak Tree
- The Beach Club
- Sandy Point Beach
- Yeamans Hall Club
- Shem Creek Park
- Isle of Palms Beach
- Deep Water Vineyard
- Front Beach IOP
- Gibbes Museum of Art
- Children's Museum of the Lowcountry
- The Golf Club at Wescott Plantation
- Splash Island Waterpark
- Splash Zone Waterpark At James Island County Park
- James Island County Park
- Whirlin' Waters Adventure Waterpark
- Charleston Aqua Park
- Morris Island Lighthouse
- Family travel hub Tips and inspiration
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- Outdoor adventure Explore nature with the family
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- Kid-friendly state parks Check out these family-friendly hikes