Hotel vacation rentals in Central Illinois

Find and book unique hotel rentals on Airbnb

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Popular amenities for Central Illinois hotel rentals

Family-friendly hotel rentals

Hotel room in Muscatine
4.8 out of 5 average rating, 5 reviews

The Loft Room at Strawberry Farm Bed and Breakfast

BettieRating, 5 stars44 months ago
This spot was so perfect for us! The loft was great for two people and we loved breakfast the following morning. The location was beautiful and a close drive from restaurants and breweries.
Guest favorite
Hotel room in St. Louis
4.9 out of 5 average rating, 892 reviews

King Redwood Bedroom at BnB in CWE!

NathanRating, 5 stars2 weeks ago
Excellent place, I will try and stay in this room every time I am in town here. It was clean and relatively quiet. I appreciate the room themes as well
Hotel room in Savoy
4.63 out of 5 average rating, 43 reviews

Dunlap Single Queen or King #3

ShirleyRating, 5 stars2 weeks ago
Had a hard time with the key card. Nice room, great location, and great price!
Guest favorite
Hotel room in St. Louis
4.87 out of 5 average rating, 713 reviews

Blue Spruce Room Queen Bed at BnB in CWE!

ChristopherRating, 5 stars3 weeks ago
We enjoyed our stay and would recommend for those who are staying in St. Louis or plan to. Be sure to plan ahead and secure one of the parking places, as it was difficult to find parking spot on the street.
Private room in Princeton
4.67 out of 5 average rating, 12 reviews

The B & B Suites at Chapel Hill . (Whole House)

MasonRating, 5 stars18 months ago
We went up to get married there! The hosts went above and beyond! 10/10 we all had our own bathroom to get ready in and we all piled into room 2 and played card games that they had provided and were able to get cozy all together and had a memorable trip. The balancing was amazing for pictures, and beautiful first thing in the morning watching the sunrise and looking at the scenery. The church was stunning, so perfect for a small intimate ceremony. It was just perfect, price was awesome for everything that came along with using the B&B. Jordan and her husband are amazing! Have recommended this place to everyone, we will be returning here to celebrate our anniversary & hopefully play a round of golf.
Guest favorite
Hotel room in Hermann
4.95 out of 5 average rating, 44 reviews

Hermann Crown's New Pet Friendly Shepherd's Suite

CassieRating, 5 stars4 days ago
The place was just a described. We liked the location was walkable and that we had access to the hotel amenities, but felt like we had a private space.
Guest favorite
Hotel room in Washington
4.93 out of 5 average rating, 28 reviews

Family Suite - Dodici Night Suites

AlanRating, 5 stars1 month ago
Never disappoints! We love staying at Lorraine’s properties! Love the quaint town square with shops and restaurants. Perfect destination for a getaway weekend. We will definitely be back.
Guest favorite
Resort in Grafton
4.94 out of 5 average rating, 69 reviews

River View Guest House, The Fishing Hole

LeeAnneRating, 5 stars6 months ago
place was fresh and very clean. walkable distance to all the bars and nightlife. I loved that there was a menu to the restaurant next door it really wrapped the night up great.

Hotel rentals with a pool

Superhost
Hotel room in Hannibal
5 out of 5 average rating, 4 reviews

Exquisite Chicago 105

KristianRating, 5 stars7 months ago
Close to town and very comfortable. Would definitely recommend and stay again!
Hotel room in Urbana
4.63 out of 5 average rating, 98 reviews

The Atrium Bedroom/Bathroom #4

SusanRating, 5 stars1 week ago
Ryan’s place was clean and just what we needed for a quick trip to UIUC. It was a great value and hope to use his place for future visits during my child’s college era. 😀
Superhost
Hotel room in Berkeley
4.46 out of 5 average rating, 13 reviews

Luxury Stay Near Airport | 2 Pools, Free Shuttle

SkylarRating, 5 stars2 days ago
Always an easy travel day when staying at renaissance!
Superhost
Hotel room in Joliet
4.55 out of 5 average rating, 20 reviews

Pure Relaxation - Breakfast Included

BryanRating, 5 stars2 weeks ago
Worth the price!! Great stay and very responsive host. Heated pool although no hot tub like in the pool picture. Would stay here again!!
Superhost
Hotel room in Perry
4.85 out of 5 average rating, 13 reviews

Cannon Dam Cabins - Motel Rooms

Dr. JRating, 5 stars7 months ago
Kurt’s place at Cannon Dam Cabins was very welcoming and clean. The beds were so comfortable! We will be back♥️
Hotel room in Joliet
5 out of 5 average rating, 3 reviews

Spacious 1 bedroom suite

CharlesRating, 5 stars1 month ago
This was a good spot. Get some much needed rest. Nice to have maid service and fresh sheets and towels. Staff was nice. It was the biggest room in a best western I’ve ever had plenty of space comfy bed and nice desk to work

Hotel rentals with a patio

Private room in St. Louis
5 out of 5 average rating, 10 reviews

Lovely spacious 2 room King suite, super quiet

KathyRating, 5 stars19 months ago
I'm a repeat visitor at Tim's. I have occasional work in the area and appreciate that his place is so close to my destination. The place is clean and comfortable. Appliances are all new. Wifi was solid for me to stream a show and maintain fast remote connection to my client's site for after hours work. There's Aldi's grocery a few blocks away so I shop and eat in for time and cost savings. Tim is super responsive, always helpful.
Hotel room in St. Louis
4.56 out of 5 average rating, 9 reviews

The West End by Cortex, Forest Park, BJC & Zoo

EarlRating, 5 stars1 month ago
Loved the repackaging of an old historical building the way you did it. Super boho spot, very rad boho decor. So cool. See you again soon!
Top guest favorite
Hotel room in Saint Charles
5 out of 5 average rating, 12 reviews

#3 Betty Bloomer Le Velo Inn

KristaRating, 5 stars2 weeks ago
We had never been to St. Louis or the surrounding area prior to booking our stay - and honestly would come back again just to book at Le Velo Inn! It is a great launch for day trips into St. Louis, but it could easily be the primary destination itself. There are many neat shops, cafes, and restaurants within close proximity, yet we found it to be very peaceful and relaxing. It is evident that the owners care about the history and character of the building. As individuals who were new to the area, we felt like we were invited into the history of St. Charles and were able to see what makes it so special. The room/suite itself was wonderful and extremely well-equipped with everything you would need for a getaway, and a luxurious one at that! It was nice to have our own private entrance to the street as well and parking was very easy and convenient. We highly recommend and would absolutely stay here again! Le Velo Inn was a gem that made our trip even more memorable!
Private room in Ferguson
5 out of 5 average rating, 4 reviews

Haunted 1905 Victorian home

JocelynRating, 5 stars18 months ago
From the moment we arrived, Melanie made us feel welcomed and ensured our comfort during our stay. One of the most memorable aspects was her willingness to share stories and engage in conversation about the house’s haunted history. Her enthusiasm surrounding the subject was admirable and intrigued me to want to know more about the paranormal. While sleeping in our room, I felt a chill travel my spine. At first, I saw a figure of man at the end of my bed and wondered if it had been a ghost or just my imagination. After falling back asleep for a while, I awoke again to look around the room. My boyfriend and I spoke to let them know we welcomed contact. A few minutes later, I head what faintly sounded like a little girl saying “Hello.” Though we only stayed here for one night, it was a memorable experience that we won’t soon forget. If I could visit here again in the future - I would. I would love to experience more of the paranormal activity of the entities that inhabit it
Top guest favorite
Hotel room in St. Louis
5 out of 5 average rating, 18 reviews

Napoleon's Retreat Burgundy Room

DavidRating, 5 stars4 months ago
Matthew was super quick to respond . Lafayette Square is a quiet secret inside of St Louis. Not a huge amount of restaurants around but covers the gambit from pub, French, ice cream and chocolate bar. All walkable. And all super friendly. Was perfect. Except should have planned two nights not one.
Guest favorite
Hotel room in Rockville
4.93 out of 5 average rating, 15 reviews

The Old Jail Inn the Bonnie and Clyde Suite

JessiRating, 5 stars1 month ago
Really awesome stay, cozy beds, can't really feel more secure than in a jail cell.
Guest favorite
Hotel room in St. Louis
5 out of 5 average rating, 17 reviews

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

LaurieRating, 5 stars2 weeks ago
10 out of 10! We briefly met the extremely friendly host. The place was amazing, unique, peaceful, everything we could have wanted. The bell tower hot tub did not disappoint. The Arch view was superb! Our room was quaint and the bathroom was beautiful! Loved the heated floor!

Destinations to explore