
Vacation rentals in Santiago
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Top-rated vacation rentals in Santiago
Guests agree: these stays are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Santiago vacation rentals
Other great vacation rentals in Santiago

Comfortable rooms in Santiago
I think it's very good choice in terms of quality and price if you go through Santiago. The host is very friendly. Recommended!.

cozy home, room and kitchen, rest on your trip.
I loved my stay with Federico’s family. They were all super welcoming and friendly. They cooked for me and we enjoyed the food while having great conversations. They also showed me around a bit despite the rainy weather. My room was clean and spacious, and the bed big and comfortable. They also gave me a towel, which is always highly appreciated. I would definitely come back next time I’m passing by Santiago. Special thanks to Diana and that amazing walk under the rain we had together!

Main room-San Miguel Clean House, Santiago.
I made a mistake in my booking and Linssi was so kind and understanding on helping me fix it :) i would highly recommend staying with her as she is lovely and i know i will return .

Standard Room - Hotel El Huésped
a nice friendly place to stay in Santiago. I stayed here between busses to Boquete and I walked from the station to the hotel and back in the morning. I found some amazing food nearby and slept well in the quiet cool room with great air-conditioning. I used the provided desk area for some writing, a pleasant surprise. if you need a stop in Santiago you can't go wrong here.

Private Room in Nata, Cocle, Panama
If you’re looking for a unique hostel experience, this is the place! It’s more like staying in a large, very unique home and building, with multiple rooms and shared spaces. I stayed on the top floor, which I thought the most interesting with its wooden, attic-like yet charming feel, as it opened onto a big deck with wonderful views and a hammock. The folks living there who receive you are wonderful, very friendly and welcoming. Lots of animals about which is fun, and beautiful trees. The breakfast which is included is also great and very complete. We had a little trouble getting into the place after hours since it’s a farm and there’s a shared main gate which is closed to keep cows in etc, at the lower part of the property - so maybe arrive earlier (before 6 pm) unless you make plans with Hermann to arrive later. Also, Hermann can take a few hours to respond, so book a bit in advance to handle all necessary communications. Was a great one night stay over for me and happy to recommend.

Casa Pueblo Ocú Herrera 2 (Ocú Herrera 2 House)
Quick stats about vacation rentals in Santiago
Total rentals
60 properties
Nightly prices starting at
$10 before taxes and fees
Total number of reviews
460 reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
30 properties allow pets
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Frequently Asked Questions
Are there vacation rentals with a dedicated workspace in Santiago?
Yes! Work meets play with ease at over 20 vacation rentals in Santiago featuring dedicated workspaces. Stay connected and productive in your home away from home.
Do house rentals in Santiago have air conditioning?
Absolutely! We offer over 20 house rentals with air conditioning in Santiago. Enjoy a tailored experience with all the comforts you desire.
Are there family-friendly vacation rentals in Santiago?
Santiago has more than 10 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.
What are the most popular amenities for Apartment Rentals in Santiago?
Enhance your stay in our Apartment Rentals with the most popular amenities: over 10 homes with air conditioning, over 10 homes with wifi, and more. Indulge in the ultimate retreat, tailored to your preferences.
Do house rentals in Santiago have wifi?
Absolutely! We offer over 10 house rentals with wifi in Santiago. Enjoy a tailored experience with all the comforts you desire.
Are there pet-friendly vacation rentals in Santiago?
Four-legged friends are welcome in Santiago. Choose from more than 30 vacation rentals for guests traveling with pets.
How much does it cost to stay in apartment rentals in Santiago?
Experience the best of Santiago with our apartment rentals, starting at about $30 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do house rentals in Santiago have a kitchen?
Absolutely! We offer over 20 house rentals with a kitchen in Santiago. Enjoy a tailored experience with all the comforts you desire.
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