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Vacation rentals in Santa Isabel District

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Top-rated vacation rentals in Santa Isabel District

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Home in La Guaira

4.25 out of 5 average rating, 4 reviews

Villa en Juan Gallego, in front of Isla Grande Colón

CatherineRating, 5 stars17 months ago

This is our second time staying at this location and it’s one of my favorite places to visit in Panama. The shallow swimming areas are great for little kids, making it very family friendly! Lanchas (local boats) can access the houses easily for you to go explore the island and surrounding areas. Bring your snorkeling gear to see all of the beautiful fish! We also loved the multiple sitting areas and hammocks outside the house for everyone to hang and enjoy the beautiful scenery. If you’re lucky, the howler monkeys will show up in the trees behind the house for you to see. We can’t wait to go back!

Home in Garrote

4.71 out of 5 average rating, 7 reviews

Cozy Cottage with garden AC/WIFI in Puerto Lindo

ChelseaRating, 5 stars8 months ago

I highly recommend! I stayed with my husband, and it was absolutely beautiful. The cabin was really cozy, extremely clean and well maintained. We came with our two dogs, and they were very pet friendly. It's such a nice environment in a peaceful tropical forest. We look forward to coming back sometime

Home in Palenque

4.83 out of 5 average rating, 12 reviews

Caribbean Paradise - Beachfront Getaway

AlexRating, 5 stars1 month ago

The place is wonderful. The house was perfect for a group of friendly families wanting to share a weekend on the beach. The rooms were spacious and the kitchen was perfect. The pool was well cared for. The gentlemen who worked for the house were very helpful and helped a lot. The only setback was a lock that there was in the area the last night, but this is out of control of the homeowners. A non-electric water pump or generator could support those moments if they happen often. Otherwise, they were all very attentive and the house was very comfortable. I would go back without thinking twice.

Apartment in Juan Gallego

4.87 out of 5 average rating, 104 reviews

Pebos Reef, apt #2, Amazing views !!

NathalieRating, 5 stars2 weeks ago

if I had or given 10 stars I would have done it. The accommodation is just paradise and fantastic, private beach, terrace overlooking the Caribbean, possibility to make a boat crossing to go to island big, what happiness. And especially Jesus, his welcome was beyond sympathy and efficiency. We arrived late and he welcomed us with a big smile. He helped us with everything, found transportation to go shopping, boat, Uber,.... Thank you Daniel also for all the information and your availability. Go ahead without hesitation!

Home in Viento Frío

5 out of 5 average rating, 5 reviews

Casa Canalú

MariaRating, 5 stars6 days ago

The house is exactly the same as the photos, with all amenities! It has everything for no leave the house, that if you have to bring everything you are going to consume because there are no restaurants in the area. We went to spend Christmas with the kids and they had a lot of fun, we used the kayak and paddle board and it was great! A pleasant stay!!

Villa in Palenque, Colón

5 out of 5 average rating, 8 reviews

Beach Front House Surrounded by 2 Private Beaches

JulieRating, 5 stars10 months ago

Leticia was wonderful. She offered many ways to make our stay what we wanted it to be. She was extremely helpful in responding to questions as we planned and offering suggestions with local insights. The roads to the house are rough. I highly recommend taking a vehicle with a higher ground clearance. Once you arrive, your private sanctuary has the amenities you need for a great stay. Other than sleeping, meals & a game around the big table, we didn't use the inside of the house much (which is how I like to spend my vacation). We snorkeled, we fished, we hamocked, we played croquette, we hiked in the jungle, we used the floating bar, we toured Portobelo, Turtle Cay, and Palenque. The on site staff was very helpful in every way. The listing for the house is very accurate. It was exactly what we wanted.

Tiny home in about 50 miles from Colon City

4.88 out of 5 average rating, 64 reviews

Cabaña de Playa

GustavoRating, 5 stars3 days ago

Spectacular place for a good rest. It exceeded our expectations. The cabin, the park, the direct access to the sea, the horses, and the landlord made everything pleasant.. Very clean everything and the beds very comfortable. Tristan was always very attentive to my inquiries and responded quickly. I recommend it without hesitation. We hope to come back someday!!!!

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Popular amenities for Santa Isabel District vacation rentals

Free parking on premises

Air conditioning

Other great vacation rentals in Santa Isabel District

Hotel room in Santa Isabel District

4.5 out of 5 average rating, 6 reviews

Hotel Macolla Beach

FrixilaRating, 5 stars18 months ago

Excellent paradise place, I recommend it. Very good service, friendly people, variety of entertainment, excellent restaurant, they have very good chefs , the manager of excellent.

Apartment in Juan Gallego

4.86 out of 5 average rating, 175 reviews

Pebos Reef, apt #1, Amazing location !

CarlosRating, 5 stars1 week ago

The stunning sea view is breathtaking. The apartment is well-maintained, comfortable, and equipped with everything needed for a relaxing stay. The personnel is excellent. Jesus –the handyman– is warm, attentive, and always ready to assist with a smile. His dedication to ensuring guests feel at home truly sets this place apart. Whether enjoying the sea view or appreciating the surroundings, this apartment is a gem. Highly recommended for a peaceful and memorable seaside retreat!

Private room in Puerto Lindo

4.52 out of 5 average rating, 66 reviews

Hostel Wunderbar Palm Room

FaeRating, 5 stars7 months ago

We have stayed at Hostal Wunderbar several times. Peter and Sylvia are always very helpful. The hostal is within walking distance of Puerto Lindo and Linton Bay Marina.

Vacation home in Juan Gallego

4.86 out of 5 average rating, 90 reviews

Pebos Reef, 12 guests, Amazing views!!

NiniRating, 5 stars2 months ago

Pebos Reef is a great place to stay. We loved that we were able to go with our dog. There were blackouts but that's not the responsibility of the house. We took advantage and left in a boat in the love tunnel, natural pools to spend the afternoon in Isla Mamey minutes from the house. We will definitely be back!

Apartment in Juan Gallego

4.83 out of 5 average rating, 6 reviews

Pebos Reef Amazing views-Suite

JosefRating, 5 stars4 months ago

Great place, the reef is beautiful the place right on the water, just fantastic! Genre again!

Villa in Juan Gallego

4.86 out of 5 average rating, 14 reviews

Fantastic KasaKai Villa

DanaRating, 5 stars5 months ago

the house expetacular super comfortable the beautiful beach,quiet,comfortable. Everything in the house comfortable and clean. We made an excellent grill. The truth is an expetacular place. 100% recommended the attention of Mr. Daniel excellent

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Monthly Rentals Santa Isabel District