Vacation rentals in Santa Cruz

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Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Costa Esmeralda

4.97 out of 5 average rating, 134 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise. Majestic Sands is located in a private beach community in Costa Esmeralda, San Carlos District, Panama. It is located a few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, Santa Clara and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.

Guest favorite

Condo in Chame

4.96 out of 5 average rating, 149 reviews

Exclusive Beachfront apartment 1Hour from Pma City

ESPECTACULAR apartamento de lujo FULL EQUIPADO con 3 recamaras (todas con vista directa al mar), 2 baños completos y medio baño de visita; cuarto y baño de servicio. Finos acabados, cocina 100% de acero inoxidable y aires acondicionados en todo el apartamento de alta eficiencia. Condominio con concepto "Hotel Style Living"; Restaurante y Bar para las noches (de Jueves a Domingo), snack bar en el area de la piscina y un Tiki Bar en la playa, ademas de cancha de Volleyball , Tenis, basketball.

Guest favorite

Townhouse in Las Lajas

4.9 out of 5 average rating, 186 reviews

Casa Inteligente Coronado Pool/Jacuzzi Private

Cozy smart beach house with a beautiful PRIVATE illuminated Pool , Jacuzzi & Waterfall. Near Coronado's main road and just 900 mts away from the closest beach. The house has 2 rooms and a comfortable living room all with a/c, 55 “ TV with Cable TV and fully equipped kitchen . Big Terrace w/ceiling fans. Up to 8 people can sleep in the house. You also can enjoy a high speed WIFI and as a option use ALEXA to control some lights, the pool, the TV and Netflix or Spotify just using your VOICE.

Guest favorite

Cabin in Chicá

4.96 out of 5 average rating, 138 reviews

Cabaña Horizonte by Casa Amaya

Relax at this unique and peaceful getaway in Cabaña Horizonte. Casa Amaya is a complex of 6 cabins located in Chicá de Chame, cool climate between 18 and 24 degrees, where you can contact nature and relax with your partner, friends or family. https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya We have an electric generator in case of outage.

Guest favorite

Villa in Punta Chame

4.99 out of 5 average rating, 110 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Guest favorite

Home in Taboga Island

4.97 out of 5 average rating, 159 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Guest favorite

Rental unit in Nueva Gorgona

4.87 out of 5 average rating, 160 reviews

Condo Nueva Gorgona Beach Front for 4

Condo Gorgona Beach Front is located on the 6th floor of Royal Palm, facing the beach with ocean views from the balcony and the room. It has 3 swimming pools, direct access to the beach, restaurant, address and more. This cozy apartment for a family or friends of 4 is an excellent economic option to enjoy luxurious amenities within the building. We treat each property like a hotel, so we invite you to enjoy this cozy apartment as you deserve. Book now!

Superhost

Home in Vista Mar Golf, Beach & Marina

4.88 out of 5 average rating, 236 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets. any inquiry please contact 66168596

Guest favorite

Rental unit in Nueva Gorgona- Panamá Oeste

4.8 out of 5 average rating, 270 reviews

Lovely Beach Apart. seafront*Royal Palm*P.Gorgona

Private beach apartment, on high floor, with ocean view, two bedrooms, one bathroom, high quality appliances, remote lighting control on any mobile devices, A/C in bedrooms and living room. Netflix and Amazon Prime services on televisions. Tennis courts, basketball, soccer, gym, barbecue area and playground, two floors of social area, swimming pool for exercise and recreation for adults & children's pool) direct access to the beach.

Guest favorite

Treehouse in Panamá Oeste

4.91 out of 5 average rating, 115 reviews

Abuela Totas Cabin #3 by AcoModo

Spectacular cabin ideal for families at Hacienda Pavo Real. A true dream refuge surrounded by fauna and animals that make this place a truly unique experience. The space was designed by the best interior designer: La Abuela Tota. Charming, cozy, quiet, this cabin is the perfect place for a romantic getaway. the songbirds will be the best wake up alarm to enjoy a beautiful day in the nature

Guest favorite

Cottage in Altos del Maria

4.93 out of 5 average rating, 116 reviews

Mountain Cottage with Great View and Heated Pool

Casa de Montaña, with spectacular views of the mountains of Altos del María, perfect to rest or spend it with family, with heated pool, spacious outdoor spaces, Smart TV and A/A in all rooms, WIFI throughout the property and fully equipped. Includes Prime Video service. It has fire pit and a gas fired BBQ. For weekend rentals saliendo Domingo, se da da late check out complimentary.

Guest favorite

Cottage in Sorá

4.94 out of 5 average rating, 105 reviews

Luxury Private Cottage in Altos del Maria

This property is situated within the gated community of Altos del Maria. Surrounded by lush forest and rivers, the loft @ Londolozi is for guests who appreciate a sense of luxury while being close to nature. While Altos del Maria enjoys a warm tropical climate, there is a cooling breeze in the mountains that is not often present in the coastal areas.