Hotel vacation rentals in Panama Canal

Find and book unique hotel rentals on Airbnb

Top-rated hotel rentals in Panama Canal

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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Hotel room in San Felipe

5 out of 5 average rating, 33 reviews

4. Heart of the Old Town: Boutique Apart-Hotel

ChelseaRating, 5 stars15 months ago

This place is gorgeous and has all the amenities. We wish we could have stayed longer. we arrived with a car and had prepaid to park in their small ramp. We thought the car would have GPS but it didn't so we realized we needed SIM cards to get around the country. Rodrigo checked us in and it was five star service from the start. He then walked us to shops until we found and purchased a SIM for our phones. The instructions were in Spanish so he then helped us set up the SIM cards. He did an informal walking tour and showed us some recommended restaurants so we could have dinner. The location is awesome and surrounded by great restaurants and shops in the heart of Casco Viejo. The rooms are gorgeous and the balcony's are fantastic for watching the bustling town. We couldn't recommend this place more!

Superhost

A bright pink flamingo float is positioned in a refreshing plunge pool. Lush greenery surrounds the area, with a terracotta pot featuring a leafy plant in the foreground. The ocean view and cloudy sky are visible in the background.

Private room in Taboga Island

4.9 out of 5 average rating, 61 reviews

Eco Lodge Garden Room 5 Oceanview Plunge Pool

MorganRating, 5 stars1 month ago

We loved our stay on the island! We loved the location and the hospitality. The owners would mingle and were happy to offer recommendations and suggestions. They knew about some of the history and happenings of the island and we’re happy to impart that information. The breakfast was very handy since the island did not have a lot of options so that was appreciated. The island is lovely and peaceful and so beautiful. The locals were friendly and would greet you in passing. It was a little slice of paradise. We love to watch the sunrise from the patio. We love the hammock and the waiting pool. We love the hikes and the sounds of the birds and the sites of the beautiful flowers. The beaches were private and beautiful on the side of the island we were at and it was exactly what we wanted.

Colorful doors featuring whimsical character illustrations create a playful atmosphere. The vibrant artwork includes a varied cast of creatures, enhancing the lively ambiance of the shared spaces. Each door stands out with unique designs, inviting guests into a creative and welcoming environment.

Private room in Panama City

4.88 out of 5 average rating, 8 reviews

El Tornillo semi-private space.

KendraRating, 5 stars3 weeks ago

The pool and breakfast are a huge bonus for this place. I was in the semi-private room, you can still hear people on the other side, but it was so much better than being in a dorm as I could get changed and leave my stuff out without any concern. They also provided me with a lock for my door because I didn’t have one. Definitely worth it for the price. I also walked around at night after meeting people at a bar and felt very safe in this neighborhood.

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Popular amenities for Panama Canal hotel rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly hotel rentals

A bedside table is positioned next to a spacious bed, featuring a simple lamp with a circular base that casts a soft glow. An elegant vase with a flower adds a touch of nature, complementing the soothing color palette of the room.

Hotel room in San Felipe

4.9 out of 5 average rating, 40 reviews

3. Apart-Hotel Boutique- Heart of the Old City

TomasRating, 5 stars42 months ago

Absolutely amazing. Place was spaciouse, clean, well equipped. Location was right in the heart of Caso Viejo and Andres was a true gentlemen our whole stay there. I would highly recommend this place to anyone looking to stay in the heart of Casco Viejo. Dining, entertainment, sight seeing walking all walking distance. truly 5 out of 5 review.

Superhost

Private room in Taboga Island

4.69 out of 5 average rating, 51 reviews

Eco Lodge Garden Room 4, Oceanview Plunge Pool

ScottRating, 5 stars3 months ago

way better than described. authentic island feel, covered hammock area, literally against the jungle.beautiful

A spacious living area features a deep blue sofa positioned across from a large wooden coffee table. A sleek kitchen with wooden cabinetry and a granite bar offers modern appliances. Natural light floods the space, highlighting the elegant chandelier above.

Hotel room in San Felipe

4.9 out of 5 average rating, 48 reviews

6. Beautiful Boutique Apart-Hotel Views & Services

LeeRating, 5 stars26 months ago

Wonderful Airbnb in Casco. La Isabella Suites was located in the heart of CV. Apartment was very spacious and comfortable. A balcony overlooked a beautiful park. Great stay. Highly recommended!

Hotel room in San Felipe

4.89 out of 5 average rating, 38 reviews

2. Boutique Apart-Hotel- Heart Old City

AndreaRating, 5 stars24 months ago

isabella Suites is a lovely apartment, comfortable and very well situated. Andres and all the staff were friendly and very helpful. My family and I really enjoyed our stay at Isabella Suites and the Casco Antiguo of Ciudad de Panama.

Guest favorite

A covered outdoor area features colorful hammocks suspended between posts, offering a relaxed seating option. The floor is composed of mosaic tiles, and views of the lush garden filled with greenery are visible in the background. A ceiling fan is also present.

Private room in Taboga Island

5 out of 5 average rating, 5 reviews

Eco Lodge Mango Room 3 Queen Plus

AudreyRating, 5 stars1 month ago

I absolutely LOVED my stay! The area is so beautiful and the room was perfect. Every single person working at the hotel was lovely and so helpful, we had great conversations. The owner even picked me up from the port area. I will definitely be back!

A metal bunk bed with a simple design occupies a minimalist space. The upper and lower sleeping areas feature neutral-colored bedding. A small glass table is positioned nearby, enhancing the functionality of the room.

Private room in Panamá

4.33 out of 5 average rating, 3 reviews

Private Room #4. 3 people

RobertoRating, 5 stars25 months ago

Comfortable place and quite focused for backpackers. The photographs match the place. A good price.

A welcoming courtyard is presented, featuring cozy seating with colorful cushions. Potted plants contribute to the greenery, while a decorative wall piece and a small water feature enhance the tranquil atmosphere. The terracotta walls add warmth to the space.

Hotel room in San Felipe

4.95 out of 5 average rating, 43 reviews

1. Boutique Apart-Hotel - Old Town Center

AndrewRating, 5 stars38 months ago

Andres is an amazing host! He was super responsive, very helpful and was extremely easy to communicate and coordinate with. The apartment was exactly as pictured and the location was very close to all the best restaurants and bars. I would definitely come back and stay here again and recommend it for anyone visiting Casco Viejo in Panama City!

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Hotel rentals with a pool

A clear swimming pool reflects the surrounding high-rise buildings and blue sky. Sunlight illuminates the water, while a white table and chairs are positioned nearby, providing a calm area for relaxation.

Hotel room in Panamá

4.67 out of 5 average rating, 64 reviews

Your second home in Panama.

MarlenRating, 5 stars1 day ago

The truth is that I really liked it, I recommend it and I would come back. The clean facilities have the option of restaurants nearby, a swimming pool, the area is quiet at night and you can rest well. The only thing is that the customer should be given the option of whether or not they want daily cleaning in the room, otherwise everything is excellent.

Hotel room in Panamá

4.44 out of 5 average rating, 18 reviews

Rainforest Suite with Breakfast! 15 min from city

RogelioRating, 5 stars13 months ago

peacefully and beautiful place...

Hotel room in Panamá

4.75 out of 5 average rating, 12 reviews

Double Suite-Apartment Hotel Príncipe

DiegoRating, 5 stars25 months ago

Super attention and check-in

A spacious sleeping area is highlighted by a neatly made bed with light bedding and two pillows. A large dark cabinet and a black chair are present, while window coverings in deep brown add privacy. A flat-screen television is mounted on the wall opposite the bed.

Hotel room in Colón

3.67 out of 5 average rating, 3 reviews

Meryland Hotel

LeahRating, 5 stars11 months ago

After I got moved to room #120, everything improved for the better and I thoroughly enjoyed my stay at the hotel. The staff was VERY accommodating. They were extremely helpful and did whatever they could to assist me. When I come back next year, I would like to stay in the same room #120. 🙏🏾🇵🇦 Víva Panama! Arriba Colón! #C3

A well-lit bedroom features a spacious bed with neutral-toned bedding. Two bedside lamps provide soft lighting, while a small nightstand holds essentials. A window allows natural light to enter, and the minimalist decor emphasizes a calm ambiance.

Hotel room in Panamá

3.33 out of 5 average rating, 3 reviews

Hotel Room with one full bed

RobertoRating, 5 stars3 months ago

Excellent

Private room in Panamá

5 out of 5 average rating, 14 reviews

Mandalas Ecolodge, Altos de Cerro Azul

JaironRating, 5 stars1 month ago

We loved the peace and privacy, we managed to share as a couple with a beautiful view and surrounded by nature. Highly recommended

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Hotel rentals with a patio

Lush greenery surrounds the entrance, featuring hanging plants and colorful decorations. Ferns cascade from hanging baskets, creating a vibrant and inviting entrance to the hostal.

Private room in Panama City

4 out of 5 average rating, 3 reviews

Nice hostel, ideal for family trips.

DanielRating, 5 stars5 months ago

Helped us in need of a place to stay very quick and in national holiday

A path of smooth stones leads through a lush garden, flanked by vibrant green plants. The pathway is bordered by concrete edges, guiding towards a gated entrance. Natural light filters through the foliage, creating a serene atmosphere within the outdoor space.

Private room in Panamá

3.8 out of 5 average rating, 5 reviews

Kakún Room 12, Cable TV, Refrigerator, Air Conditioning.

JimmyRating, 5 stars38 months ago

Awesome place in a very nice neighbourhood. One of the most spacious rooms I had so far with a private bathroom and a fridge. Shared kitchen has everything you need and grocery stores and restaurants at walking distance. Friendly staff, fast and stable internet. Highly recommended great value for your money.