Guesthouse vacation rentals in Mississippi

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Mississippi guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
Guesthouse in Oxford
5 out of 5 average rating, 41 reviews

Clear Creek House

JimRating, 5 stars6 months ago
Beth’s place was absolutely beautiful . While being quiet and private, it was an easy, quick drive to Ole Miss. It was very clean and well stocked with anything we needed. The beds were super comfortable, and the whole place was cozy. Beth is the sweetest. We will be back!
Top guest favorite
Guesthouse in Laurel
4.98 out of 5 average rating, 742 reviews

Mallorie's Carriage House - Rated Top 1% Worldwide

MelissaRating, 5 stars2 days ago
Had a wonderful visit at Mallorie’s Carriage House! The communications and recommendations were excellent along with detailed directions to get there and get ourselves in. So many extra touches -she really went all out to make our stay comfortable. Beautiful neighborhood and we were able to walk into downtown Laurel very easily. We would definitely stay again!
Top guest favorite
Guesthouse in Oxford
4.97 out of 5 average rating, 29 reviews

The Hawk's Nest II ** 1 mile walk to square

HollyRating, 5 stars3 weeks ago
Priscilla was a great host. She was very response and gave very detailed information about the house. The location doesnt get much better. Very quiet neighborhood and close to everything. The unit was very large and spacious and the beds were very comfortable. It is downstairs from their house so you will hear the pidder padder of little feet upstairs during normal hours but we did not mind at all. We had a great stay!
Guest favorite
Private room in Tishomingo
4.91 out of 5 average rating, 260 reviews

Bear Creek Saloon Guesthouse/ 1st Floor Studio Apt

AliceRating, 5 stars4 days ago
This is a convenient overnight if you’re cycling the Natchez Trace. We were doing it without a support vehicle and it worked out very well, especially as the local grocery store could shuttle us to shop for our groceries. The studio apartment and porch are comfortable.
Top guest favorite
Guesthouse in Clarksdale
4.93 out of 5 average rating, 67 reviews

Honey Hill Carriage House

PamelaRating, 5 stars3 weeks ago
Great host, very accommodating and responsive to questions.
Guest favorite
Guesthouse in Oxford
5 out of 5 average rating, 56 reviews

Farm View Guest House

MattRating, 5 stars4 months ago
Margaret’s guest house is the perfect place to stay when visiting Ole Miss/Oxford. Located only ten minutes from town, once on the property you feel like you are a thousand miles away. Extremely comfortable lodging on a former cattle farm, this was the perfect place for me, my wife and daughter to stay while visiting our son for Thanksgiving and the Egg Bowl. The guest house has all comforts of home, and the surroundings proved to be a great place to take a walk and relax. With my son being a senior, I only wish we had discovered Margaret’s place earlier and could have stayed here more.
Guest favorite
Guesthouse in Long Beach
4.96 out of 5 average rating, 150 reviews

Relaxing getaway in a peaceful resort setting.

JacobRating, 5 stars8 months ago
Great place. Much nicer than I expected. Cozy and had all the creature comforts you could ask for. Games and movies available. Wifi. Super nice pool with a friendly dog that occasionally comes and says hello. But doesn't stick around long and definitely doesn't bother you. Actually kind of stand off ish. My wife was in love! We really enjoyed ourselves.

Guest house rentals with a patio

Top guest favorite
Guesthouse in Laurel
5 out of 5 average rating, 52 reviews

The Little Manor on 7th

DebraRating, 5 stars2 months ago
The Little Manor on 7th Ave was the perfect place to spend our long weekend in Laurel. It was so charming and peaceful yet close to downtown Laurel. Suzi decorated the bungalow to be cozy and comfortable with every detail thought of… right down to the snacks, water and coffee.
Guest favorite
Guesthouse in Madison
4.95 out of 5 average rating, 22 reviews

Adorable one bedroom guesthouse with lake

MarkRating, 5 stars1 month ago
This place is truly a slice of heaven and Kathy and her husband were Godsends in a time of need. Next time we need an escape we’ll be looking at this place.
Guest favorite
Guesthouse in Long Beach
4.91 out of 5 average rating, 134 reviews

The Cottage at Pino (Low clean fee)

EvanRating, 5 stars2 weeks ago
Great place to stay. The pool wasn’t open but when it is it will be the icing on the cake for ppl.
Top guest favorite
Guesthouse in Poplarville
5 out of 5 average rating, 53 reviews

Adorable cottage with pool and hot tub

JoRating, 5 stars1 day ago
The guest house is a true gem! It has a charming interior and is located in a peaceful setting. Cindy, the hostess, is friendly and responsive. She lives nearby, which I find comforting because I usually travel to Poplarville alone. However, she allows her guests privacy. This is a wonderful place to stay.
Top guest favorite
Guesthouse in Laurel
4.99 out of 5 average rating, 282 reviews

Woodland Cottages- Sycamore

GerryRating, 5 stars1 week ago
Fabulous location and great hosts. Great conversations with hosts about their place, their experience with Home Town. Felt like we’ve have been friends for years. Good recommendations for things to do and restaurants etc. around town. The Sycamore Cottage was a perfect comfortable place away from home. Felt very cozy and had everything you need. Great porch and rocking chairs to sit late afternoon in the sun. Wonderful shower and comfortable swivel rocking chairs inside. Great landscaped garden with unique carvings and art work. Isao picked us up with luggage in golf cart and took us short trip to room. No need to lug bags around. Great service. Would stay again at Kathy and Isao’s wonderful Airbnb.
Top guest favorite
Guesthouse in Meridian
4.94 out of 5 average rating, 119 reviews

Country Club Cottage - GREAT location!

IreneRating, 5 stars2 days ago
Second stay here and love it! Super comfortable and clean!
Superhost
Guesthouse in McComb
4.77 out of 5 average rating, 22 reviews

Oasis in the Country

RyanRating, 5 stars2 months ago
Thomas is a great host! We love staying at his little pool house.
Top guest favorite
Guesthouse in Bay St. Louis
4.97 out of 5 average rating, 63 reviews

Adorable One bedroom guest house with patio

MelissaRating, 5 stars4 months ago
A wonderful place to stay. The host are very nice and personable. We would stay here again if we are ever back in town.

Guest house rentals with a washer and dryer

Guest favorite
Guesthouse in Kiln
4.87 out of 5 average rating, 176 reviews

T-Bohn Bayou Bungalow

KarenRating, 5 stars4 days ago
It’s a peaceful place in the bayou. Tom was a great host. If I’m in the area again, I’d absolutely stay again. If you’re looking for a high end kitchen go elsewhere. Appliances are old but all were clean and worked perfectly. Well stocked with spices and cooking supplies. Sheets were so soft and the ac was cold. Enjoyed the pool and hot tub. And was so happy to let my pup get some off leash time. Thanks Tom!
Guest favorite
Guesthouse in Waveland
4.88 out of 5 average rating, 111 reviews

Close to the Beach / Lovely and peaceful

AmandaRating, 5 stars1 week ago
This place was amazing!!! Sean was awesome and responsive!! Even gave us some ideas on what was going on in the neighborhood! I loved that the showers had body wash and shampoo and conditioner!! I wish every host was as amazing as them!!!
Top guest favorite
Guesthouse in Gulfport
5 out of 5 average rating, 51 reviews

*Hidden Gem Arcade near Beach (guest house)*

AlanRating, 5 stars3 months ago
Came for New Years and a tournament. Close to town but far enough away to not hear a lot of noise.
Guest favorite
Guesthouse in Ocean Springs
4.91 out of 5 average rating, 253 reviews

Twin Oaks Tiny House

EmersonRating, 5 stars2 months ago
Absolutely the most lovely hosts we’ve ever had the pleasure of staying with! The tiny house is exactly as pictured. The outdoor photos don’t do it justice! Beautiful walking trails all around the property. Perfect distance to downtown Ocean Springs. My only wish would be more access to certain kitchen tools, but overall absolutely worth it. I hope to find the time to stay there again!!
Guest favorite
Guesthouse in Tupelo
4.94 out of 5 average rating, 201 reviews

Tupelo Guesthouse

CarolynRating, 5 stars5 days ago
Absolutely loved don's place !! The view was beautiful with the lake ! very relaxing & the bed swing was a great added resting spot !! It was close to town everything was clean & comfy!!!!! Don was exceptionally nice! 😊 we will be back
Top guest favorite
Guesthouse in Oxford
4.98 out of 5 average rating, 117 reviews

Magnolia Cottage

MariaRating, 5 stars3 weeks ago
Magnolia Cottage was absolutely charming, clean, welcoming, quiet and peaceful. Easy ride to Ole Miss. my stay was great. Host made communicating easy!
Top guest favorite
Guesthouse in Ocean Springs
5 out of 5 average rating, 11 reviews

Gulf Front Copper Pelican

ShaneRating, 5 stars6 months ago
Very friendly host. They had a plate of cookies made when we checked in. Met the host and they made sure we had everything that we needed.
Top guest favorite
Guesthouse in Brandon
4.99 out of 5 average rating, 681 reviews

The Cottage on College Street

TycerraRating, 5 stars1 week ago
This was an excellent spot for my siblings and me. There was plenty of space, and it was wonderfully peaceful. We received a warm welcome, and they even offered us some extra pizza they had & drinks. I will definitely come back, even if it's just for myself.

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