Vacation rentals in Mission District, San Francisco

Book unique vacation rentals, houses, and more on Airbnb

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Popular amenities for Mission District, San Francisco vacation rentals

Stay near Mission District, San Francisco's top sights

Mission District355 locals recommend
Oracle Park596 locals recommend
Mission Dolores Park1,244 locals recommend
Philz Coffee908 locals recommend
Whole Foods Market903 locals recommend
Tartine Bakery767 locals recommend

Other great vacation rentals in Mission District, San Francisco

Top guest favorite
Home in Oakland
4.99 out of 5 average rating, 120 reviews

Beautiful Home. Gorgeous Views. Five Bedrooms.

MarielaRating, 5 stars1 week ago
The house is very cozy and comfortable. The area is quiet and feels safe. We were allowed to arrive early without even asking. The house seems decorated with love, and the view is incredible. We went to visit UC Berkeley with our 5 teenage kids and dog, and everyone loved the house. We would love to stay there again.
Guest favorite
Cabin in Bolinas
4.95 out of 5 average rating, 64 reviews

The Biggest, Little, Surf Cabin

KimRating, 5 stars1 week ago
Christina's place was the perfect getaway that made us feel right at home. The space was clean, light, bright, comfortable and just what we needed for our weary NYC souls. The area is absolutely beautiful and a short walk to Agate beach which I fell involve with. Christina was so responsive and her place is extremely private and is exactly as described. It exceeded our expectations. My only wish is that we could have stayed longer. I would 100% say there again and again and again!!!
Guest favorite
Apartment in South San Francisco
4.92 out of 5 average rating, 37 reviews

Sparkling Clean Newly Remodeled 1BR near SF/SFO+EV

AlyssaRating, 5 stars1 month ago
We found George's place last minute on our way into San Francisco and it was the perfect place for a restful night after a long day of flying. In the morning it was a nice 10 minute for some delicious breakfast, would definitely book again!
Superhost
Home in North Oakland
4.81 out of 5 average rating, 63 reviews

Charming Temescal Retreat

KayaRating, 5 stars1 month ago
Kathryn’s place was a perfect place to stay for a night. There was a communal feel in the kitchen and living room space, yet enough space and privacy (we were traveling with two other couples) and all amenities we needed. Super clean, light, and airy space with a sweet backyard garden. Very walkable and safe area too!
Superhost
Tiny home in Mill Valley
4.94 out of 5 average rating, 235 reviews

Base Camp Muir Woods

HollyRating, 5 stars3 weeks ago
Beautiful place to stay, hike, wake up over looking Muir Woods-can’t beat it! Easy to relax, enjoy nature, go to the beach or drive into Mill Valley for anything you want. Fun to stay in a Tiny home -thank you
Guest favorite
Home in Richmond
4.96 out of 5 average rating, 74 reviews

Quiet Gem w/city access 2BR 1BA

JanRating, 5 stars1 week ago
Charming, quiet and spacious with a beautiful backyard. Lots of natural light, beautiful original hardwood floors, comfortable beds. Big dining room table ideal for games, well equipped kitchen. We loved this quiet neighborhood convenient to services including a nearby Trader Joe's. It's also just a few minutes walk from El Cerrito Natural Grocery and Annex, a fantastic spot. Friendly, responsive hosts. We will definitely stay here again when we're in the area!
Superhost
Apartment in Daly City
4.9 out of 5 average rating, 20 reviews

SF Coast Work/Play/Hike + HotTub

NelsonRating, 5 stars1 month ago
We had a great stay at this Airbnb! The place was clean, comfortable, and well-equipped with all the essentials, including strong WiFi, parking, and bathroom amenities. The location made it easy to get into San Francisco while still having a quiet place to return to. Also great views and near to hiking. What really stood out, though, was the host’s incredible responsiveness. We had a lock issue during our stay, and they went above and beyond—driving an hour and a half to personally bring us a key to the side door to ensure we felt safe. That level of dedication and care made all the difference, and we truly appreciated it. Highly recommend this stay to anyone looking for a convenient and well-hosted experience!
Guest favorite
Home in Noe Valley
4.92 out of 5 average rating, 169 reviews

Noe Valley entire guest suite overlooking downtown

TrishaRating, 5 stars6 days ago
Our stay at Veronica's exceeded all expectations. The location was perfect—everything we wanted to see was just a short 10–15 minute drive away. The home itself was spotless, spacious, and looked exactly like the photos. Veronica was an exceptional host, always quick to respond and incredibly kind throughout our stay. We couldn’t have asked for a better experience!

Quick stats about vacation rentals in Mission District, San Francisco

  • Total rentals

    890 properties

  • Total number of reviews

    37K reviews

  • Family-friendly rentals

    280 properties are a good fit for families

  • Pet-friendly rentals

    160 properties allow pets

  • Rentals with a pool

    50 properties have a pool

  • Rentals with dedicated workspaces

    510 properties have a dedicated workspace

Destinations to explore