
House vacation rentals in Mesilla
Find and book unique houses on Airbnb
Top-rated house rentals in Mesilla
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mesilla house rentals
House rentals with a pool

Casita at the Mediterranean Palms Estate
This was a perfect stay, and I'd give more stars if I could, especially having been to over 30 AirBnbs. Even better than the pictures and description. Access to the yard and pool house felt like a fancy hotel, with the beautiful sky and mountains in the distance. Incredible value. Everything was comfortable, clean, and we had what we needed provided by the hosts. The snacks and all of the helpful instructions were so appreciated. Very convenient to the missile range, beautiful parks and national park areas, and local essentials were always nearby. We loved so many of the host's recommendations. We felt safe and like we had complete privacy. The property is beautiful. Thank you to Theodore and his wife. They were excellent communicators, and their dog brought us so much happiness. Already wishing we didn't have to leave, but we would go back in a heartbeat, and hope to soon.

Casa Luna | Pool | Breathtaking Views
What can I say about Casa Luna? That is not only beautiful, it had everything you needed for your visit. We felt right at home the moment we walked in. This was our second leg of our trip and I wish I would have had an extra day or two to enjoy the home and the area. The views are outstanding and the sunrise was beautiful from the patio. The pool was and added bonus. I will definitely choose Casa Luna as my go to place to stay while visiting friends in the Las Cruces.

Private Oasis Near Old Mesilla with Pool/Jacuzzi!
Over all this was a peaceful and beautiful experience. The home was spotless, and the bed was incredibly comfy, ensuring a restful stay. The hosts were very kind and responsive, which made the experience even better. However, I was a bit disappointed with a few things. The home is listed as a 3-bedroom property, we were limited on bedrooms we actually had access to. Since I rented the entire house, I expected access to all the bedrooms(I did find this listed in the add.rules). Regardless if the entire home is rented the entire home should be accessible. Additionally, the listing mentions a hot tub and heated pool, but you have to pay extra for the hot tub to be hot and for the pool to be heated. The website states that all fees are included, so this felt a bit misleading. Again this was mentioned in the additional rules , however very misleading in title of the listing. Had I had access to all 3 bedrooms and the hot tub and pool been heated w/o additional fees, it would be 10/10 stay

Desert Escape Year Round Pool,Hot Tub&Game Room
Booked this beautiful home for my family. My mother-in-law is hard to please and she had nothing but great things to say about this house. There were plenty of toys and games for my boys to enjoy inside and out. Pool toys were available and easily accessible. When a request was made someone was there to assist promptly. I would recommend this house to any family visiting Cruces or White Sands.

Family-Friendly Escape with Pool & Play Area
Beautiful home! Enough room to make it comfortable for a week stay. Had everything we needed.

Desert Paradise, with hot tub
The home was beautiful and spacious for our family of 5. We really enjoyed the backyard, hot tub and pool (which we paid to have heated). The pool volleyball was also a big hit. The backyard abuts a desert nature park, which has some nice walking trails. The home is in a great location to visit White Sands National Park, downtown Las Cruces and great hiking at Organ Mountain. Ary was a very friendly and responsive host. We would highly recommend staying here!

Desert Oasis with Pool
Veronica and Jorge's place is INCREDIBLE!!! So well decorated, comfortable and clean! They actually have comfortable and nice seating spaces and it was perfect for our family of 4 (+1 friend). We used it as our hub with my parents who were renting nearby as it had everything we needed and room to spread out. What an amazing house! WOULD 110% SUGGEST booking this GEM!

Year Round Heated Pool, Fast Wifi, Pet Friendly
Wow! What a magical place to stay for Christmas. Lisa went out of her way to make it feel Christmasy for my son that was feeling homesick. House was better than described, everything you could possibly need or want was thought of. We loved our stay!! One thing not mentioned is there are 7 saucer sleds for sledding in White Sands National Park. We had a blast doing that, be sure to buy the wax at the gift shop to make the sleds fly. The hosts were extremely responsive to a small issue we had, sending a plumber over within minutes to save the day. We had lots of fun in the pool and liked scampering over to the hot tub after to warm up. This place was a hit for everyone in the family from grandparents, to us, to our son. Also, the kitchen was really nice and very well equipped. We were able to make a beautiful Christmas dinner easily. There are so many extra sweet touches in this place, you will have a blast discovering them all. Stop searching, just stay here!!!
Weekly house rentals

Cozy & Comfortable New Mexico Home
Clean, comfortable home, nice for a family traveling with a small dog. Neighborhood felt safe. Easy to get in and out, and garage parking is available

Cozy Mountain View near White Sands
We felt at home at Lori’s house! The house was clean, the beds were comfy, and it was a great location. We even found sleds to borrow to take to the sand dunes! We are looking forward to staying again in the future.

Crimson Cottage near NMSU
Jannea was a fabulous host for our corporate healthcare traveler. She really enjoyed her time in Las Cruces and beautiful and safe home. We appreciated her communication and accommodations!

*Colorful Rustic Casita w/3BR
Beautiful clean home, very grateful for them to have opens their home to us o such short notice.

Southwestern Comfort Stay 2
The house is stunning and very well decorated. The kitchen is fully stocked with anything a cook might want or need. He has nice furniture. Gorgeous decorations. The master bath is amazing. Love the backyard. The location is secluded but close to mesilla.

Your modern home away from home 3BR 2 BTH
Great place to stay- Everything was in good working order. Monster TV!! Comfortable beds. didn't use the grill or outside but it was as described. would highly recommend!

Jade House! HotTub&Game Room Close to White Sands
Our stay was very comfortable. The house could have been a bit cleaner but other than that it was very roomy. The location was perfect for us and we will definitely keep this house in mind for future trips to Las Cruces

Hot Tub + Arcade Games, Brand New Modern Home
Wonderful stay here while we visited our kids. Safe and secure. Appreciate being able to park in the garage. Beautiful,clean, bright house.
Private house rentals

Spacious Valley Cottage
The home is an older home, but Esther has made it very homey and comfortable! I love the way she has decorated it.

Lotus Blossom: serene, quiet, relaxing!
Great place to stay for what we needed. Kyle is an excellent host! We enjoyed our stay very much.

Elite Casita w/ indoor Jet Tub & EV
We made a last minute reservation because my dad was moved to the hospice unit in Las cruces. This was a very sad time for us, but Polly's house gave us refuge. the house was ready and clean and sparkling for us. It provided a safe place for us to land. We are grateful.

Modern Luxury Home
This was our 2nd time at this beautiful home, and we were very happy to stay here. Our whole family commented on the luxurious beds, as well as the cleanliness of the home. It smells so fresh, has everything you need, and has great spaces to relax in. If you want to treat yourself and your loved ones to a top-rate place to stay, look no further.

Cozy Las Cruces Home
One of the best airbnb experiences ever. The house was well equipped with everything my family needed for our short stay in Las Cruces.

Lus Solar Tranquila gated community/golf course
We love staying at Kurt's Las Cruces home. He's so easy to communicate with and the house has everything we need for an extended stay. We particularly enjoy the view as well as the feeling of security and privacy.

Entire Home- Vista Montaña (your White Sands Base)
We loved the home, Erika was also very quick to respond and very friendly. The home was near dripping springs and not too far from white sands! 10/10

Sweet Escape with Spa bath
Krystal was responsive and went out of her way to make sure we had everything we needed. The house was comfortable and had everything we needed and more! I would recommend her place, you have ever you need.
Quick stats about house rentals in Mesilla
Total rentals
30 properties
Nightly prices starting at
$60 before taxes and fees
Total number of reviews
2.2K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Destinations to explore
- El Paso Vacation rentals
- Ciudad Juárez Vacation rentals
- Ruidoso Vacation rentals
- Las Cruces Vacation rentals
- Cloudcroft Vacation rentals
- Truth or Consequences Vacation rentals
- Silver City Vacation rentals
- Alamogordo Vacation rentals
- White Sands Vacation rentals
- Elephant Butte Vacation rentals
- Deming Vacation rentals
- Salt River Vacation rentals
- Pet-friendly rentals Mesilla
- Rentals with a patio Mesilla
- Rentals with a fireplace Mesilla
- Rentals with a fire pit Mesilla
- Rentals with pools Mesilla
- Rentals with outdoor seating Mesilla
- Rentals with a washer and dryer Mesilla
- House rentals Doña Ana County
- House rentals New Mexico
- House rentals United States
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes