Vacation rentals in Des Moines County
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Des Moines County
Guests agree: these stays are highly rated for location, cleanliness, and more.
Home in Burlington
5 out of 5 average rating, 37 reviewsThe Happy, Hippie Homestead 3BRM Sleeps up to 10
This was a nice place to stay in Burlington while we were visiting family for the holidays. There was a small fenced area that our dogs were able to use outside, which was very helpful.
Apartment in Burlington
4.94 out of 5 average rating, 18 reviewsBrand New 2 BR Downtown Burlington! 302N
My family had an absolutely wonderful stay at this Airbnb! The space was spotless, beautifully maintained, and felt so inviting. The location couldn’t have been more perfect—right in the heart of Burlington, close to everything we wanted to explore. What made it even more special was the charming Christmas decor, which added a magical touch to our trip and made us feel right at home for the holidays. Every little detail was thought of, and it’s clear the host takes great pride in making their guests feel welcome. This property is easily at the top of our list for Burlington stays, and we can’t wait for our next visit.
Home in Oquawka
4.91 out of 5 average rating, 35 reviewsOquawka Cottage With River View
This is the second time we’ve stayed there. Always clean, and definitely a relaxing place to stay!
Townhouse in Burlington
4.97 out of 5 average rating, 34 reviewsMosquito Park Condo
John did an awesome job of making sure we had all the information needed to check in and recommendations. The condo is impressively well stocked and it is very apparent he cares about the guest experience.
Home in Burlington
4.87 out of 5 average rating, 101 reviewsCheerful Bungalow with original woodwork
Beautiful home, and nice neighborhood. Very close to downtown and everything else you would need.
Loft in Burlington
4.99 out of 5 average rating, 244 reviewsThe Peacock Loft / Spacious Artistic Loft
A great overnight stay! A beautiful space with privacy and lots of room. Would definitely stay here again!
Home in Burlington
4.99 out of 5 average rating, 175 reviewsSnake Alley Inn, a one-of-a-kind location.
Snake Alley Inn was great. Even better than the description. The old house has been completely renovated and is in excellent condition. It was a great place for our family. The only negative is the walk up beautiful Snake Alley. Taking luggage and supplies up and down was hard, no driving during winter months. Snake Alley was decorated beautifully for the Holidays. We had our private light show.
Home in Burlington
4.91 out of 5 average rating, 133 reviewsThe Fleetwood Bungalow with Dreamy Porch
Great place to stay. I saved money rather than getting a hotel. Felt like home. Easy to use tv. The lock to get in was easy to use and secure. Excellent communication with the host. I will stay here again if I’m in town.
Home in Oquawka
4.85 out of 5 average rating, 13 reviewsWarm & inviting 3 BR/4 beds, pet friendly home
Very comfortable place to stay with my family. The living room was super cozy and a great space for us all to hang out and catch up.
Apartment in Burlington
4.94 out of 5 average rating, 113 reviewsRiverview Upstairs Apartment
Space was exactly as described. Safe neighborhood. Comfortable beds. Clean. Pet friendly was very important to us and we and our dog felt right at home! We will be back to Burlington often to visit family and hope to stay at Katrina’s again.
Home in Sperry
4.92 out of 5 average rating, 13 reviewsPorches and Pines Farmhouse
Amazing place. Made lifetime memories in this amazing space. Thank you so much for making such a warm inviting space in our area! We don’t have many locations like this around eastern/south eastern Iowa!
Loft in Burlington
4.98 out of 5 average rating, 115 reviewsStudio in Downtown Burlington with river view
Always a great place to stay.
Vacation rentals for every style
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Popular amenities for Des Moines County vacation rentals
Other great vacation rentals in Des Moines County
Home in Burlington
4.73 out of 5 average rating, 90 reviewsCheerful 2 bedroom home, outside deck, parking
David’s place was great! My wife and kids and I came in to town for a basketball tournament and the location was perfect.
Private room in Danville
4.94 out of 5 average rating, 48 reviewsGeode Retreat
We used Janet’s place for a cousin’s reunion of 6 people. One of our group grew up in Danville so she was our tour guide for 2 days. Janet’s place is very comfortable and spacious, we all agreed we would have no problems using her place again if we needed to.
Home in Burlington
5 out of 5 average rating, 77 reviewsMiss Victoria- T.L. Porter House
Thank you for another lovely stay! We really enjoy celebrating Christmas with our family here, the house is decorated beautifully and it's the prefect size for our family of 4.
Apartment in Burlington
5 out of 5 average rating, 261 reviewsDowntown Living
This is my family's "go-to" place when we visit Burlington. Great location, plenty of space, always spotless, and Jeff is great to work with.
Private room in West Burlington
4.97 out of 5 average rating, 64 reviewsFalcon Place
I had an amazing stay at Melanie and Steve place! The room was exactly as described—clean, cozy, and in a fantastic location. Melanie and Steve were incredibly responsive and helpful, making the check-in process smooth and hassle-free. The place had all the amenities I needed, and the attention to detail was evident in every corner. I especially appreciated the comfortable bed, well-stocked bathroom, and tranquility environment. The neighborhood was lovely. I felt right at home during my stay, and I would definitely recommend Melanie and Steve to anyone visiting Burlington/West Burlington, Iowa. Thank you, Melanie and Steve, for being such a great host!
Home in Burlington
4.92 out of 5 average rating, 52 reviewsThe EmeraldFirefly
We’ve been coming to Burlington for years to see relatives and never thought to rent an AirBNB, so this was our first. Great spot. Clean. Convenient. Deb, the host, was a tremendous communicator and very hospitable.
Apartment in Burlington
4.94 out of 5 average rating, 16 reviewsSpacious New 2 BR Downtown Burlington! 301S
Our "Thanksgiving" stay at Danielle's in Burlington, Iowa was great! Home was cozy, clean, and comfortable and the surrounding had so much to do and walkable! We will definitely stay here again when we come back to visit family!
Home in Burlington
4.83 out of 5 average rating, 80 reviewsMagnolia cottage
We enjoyed our time in this cozy house. Everything was very clean, the couches are super comfortable, and I liked how easy it was to work the TV. The backyard is perfect for a dog. We will book here again in the future.
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