Villa vacation rentals in Isle of Palms
Find and book unique villas on Airbnb
Top-rated villa rentals in Isle of Palms
Guests agree: these villas are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Isle of Palms villa rentals
Villa rentals with a pool
Villa in Seabrook Island
4.92 out of 5 average rating, 89 reviewsGreat Rates! Screen Porch! Pool!
Villa in Seabrook Island
4.84 out of 5 average rating, 61 reviewsPrivate island villa with luxury resort amenities!
Villa in Seabrook Island
4.91 out of 5 average rating, 33 reviewsUpscale Villa, Amenity Included! Dog Friendly
Villa in Seabrook Island
4.86 out of 5 average rating, 37 reviewsSeabrook Golf View Villa: Pickleball, Pool, Bike
Villa in Seabrook Island
4.93 out of 5 average rating, 57 reviewsNewly Remodeled Villa, 5 Minute Walk to Beach
Villa in Edisto Island
4.96 out of 5 average rating, 23 reviewsWaves of Change
Villa in Seabrook Island
4.95 out of 5 average rating, 60 reviewsBeautiful and Spacious 2 Bedroom Courtside Villa!
Villa in Folly Beach
4.82 out of 5 average rating, 62 reviewsComfy Cool-Pool-River Views-Beautifully Updated
Private villa rentals
Villa in Kiawah Island
4.96 out of 5 average rating, 98 reviewsSpacious new 2BR Villa across beach near Sanctuary
Villa in Seabrook Island
4.73 out of 5 average rating, 11 reviewsBeach and Golf Paradise | Vaughan Villa
Villa in Edisto Island
4.74 out of 5 average rating, 54 reviewsLoft-e-Lagoon *No Cleaning Fee*
Villa in Edisto Island
4.97 out of 5 average rating, 37 reviewsRelax in a Happy Place
Villa in Seabrook Island
4.87 out of 5 average rating, 54 reviews711 Spinnaker centrally located to EVERYTHING!
Villa in Kiawah Island
4.73 out of 5 average rating, 30 reviewsSpacious & Steps to the Beach at Kiawah Island
Villa in Mount Pleasant
4.94 out of 5 average rating, 16 reviewsCoastal 3BR in Old Village with patio & yard
Villa in Isle of Palms
4.92 out of 5 average rating, 12 reviewsPort O' Call B103 - Oceanfront Oasis! Walkout!
Luxury villa rentals
Villa in Seabrook Island
4.93 out of 5 average rating, 14 reviewsLuxury Seabrook Isl Beach Condo
Villa in Kiawah Island
5.0 out of 5 average rating, 26 reviewsOcean Front! Beach is steps away. Clean and Crisp!
Villa in Johns Island
Penthouse in popular, centrally located new constr
Villa in Seabrook Island
Seaside Therapy - An iTrip Vacations Home
Villa in Sullivan's Island
4.59 out of 5 average rating, 22 reviewsHaven by AvantStay | Luxury Beachfront Retreat
Villa in Kiawah Island
4.94 out of 5 average rating, 17 reviewsOceanfront Windswept Villa
Villa in Isle of Palms
5.0 out of 5 average rating, 5 reviewsOceanfront Villa in Wild Dunes! Community Pool!
Villa in Folly Beach
4.56 out of 5 average rating, 16 reviewsLarge 4BR Oceanfront 4th-Floor | Balcony | Pool
Quick stats about villa rentals in Isle of Palms
Total rentals
70 properties
Rentals with dedicated workspaces
40 properties have a dedicated workspace
Rentals with a pool
70 properties have a pool
Family-friendly rentals
60 properties are a good fit for families
Total number of reviews
1.3K reviews
Nightly prices starting at
$170 before taxes and fees
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- Rentals with pools Isle of Palms
- Rentals with a patio Isle of Palms
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