Guesthouse vacation rentals in Charleston
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Top-rated guesthouse rentals in Charleston
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Charleston guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Charleston
Spacious Daniel Island Apartment
Guesthouse in James Island
Island Oasis—Near Downtown
Guesthouse in Ridgeville
Pond House Bungalow at Natural Gathering Grounds
Guesthouse in Summerville
Nina's Cottage -Historic Downtown Summerville
Guesthouse in Park Circle
Park Circle Jungalow Loft
Guesthouse in Johns Island
Private waterfront apt in the oaks
Guesthouse in Mount Pleasant
5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!
Guesthouse in Mount Pleasant
Green Garden Studio @greengardenstudio2017
Guest house rentals with a patio
Guesthouse in Johns Island
Cozy Cottage! 5 mins from Kiawah!
Guesthouse in West Ashley
Studio Apartment Minutes to Downtown Charleston
Guesthouse in West Ashley
Private Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Hanahan
The Violet Villa w/ no cleaning fee
Guesthouse in West Ashley
Spacious 1 bedroom cottage in Avondale
Guesthouse in West Ashley
BoHo styled casita in adorable neighborhood...
Guesthouse in Mount Pleasant
Coastal Charm: Village Hideaway
Guesthouse in James Island
1/1 sleeps 3 ADU Modern+Amazing!
Guest house rentals with a washer and dryer
Guesthouse in Summerville
Tiny Oak Cottage in Historic Downtown Summerville
Guesthouse in James Island
James Island "La Casita" Nestled btw Beach & City
Guesthouse in Mount Pleasant
Cozy Apartment in Mount Pleasant
Guesthouse in Park Circle
Newly Renovated Studio in Park Circle
Guesthouse in Mount Pleasant
#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Guesthouse in Mount Pleasant
Beach, downtown, Alhambra Hall weddings so close!
Guesthouse in Charleston
Detached Guest Suite
Guesthouse in Mount Pleasant
Old Mt. Pleasant/Shem Creek close to Sullivans/DT
Quick stats about guesthouse rentals in Charleston
Total rentals
230 properties
Rentals with dedicated workspaces
100 properties have a dedicated workspace
Rentals with a pool
10 properties have a pool
Pet-friendly rentals
50 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
23K reviews
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