Mansion vacation rentals in Florida Keys
Find and book unique mansions on Airbnb
Top-rated mansion rentals in Florida Keys
Guests agree: these mansions are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Florida Keys mansion rentals
Luxury mansion rentals
Home in Miami
4.99 out of 5 average rating, 131 reviewsBy Luhos: Luxury House w/HeatedPool ,Jacuzzi & BBQ
Nov 24 – Dec 1
Home in Marathon
4.92 out of 5 average rating, 24 reviewsSerenity Bay Estate-FL Keys Best Kept Secret! Beau
Oct 12 – 19
Home in Marathon
5.0 out of 5 average rating, 6 reviewsSalty kisses beach house
Apr 10 – 17
Home in Marathon
4.97 out of 5 average rating, 32 reviews2023 New Modern Private Dock+Heated Pool+Jacuzzi
Nov 26 – Dec 3
Home in Cudjoe Key
4.95 out of 5 average rating, 22 reviewsWhite Vacation Home. Free cancellation see details
Nov 16 – 23
Home in Marathon
4.89 out of 5 average rating, 9 reviews4BR Sombrero Beach House on Canal w Dock & Pool
Jun 12 – 19
Home in Marathon
5.0 out of 5 average rating, 8 reviewsWaterfront Escape -VACA-23-408
Sep 2 – 9
Home in Marathon
4.98 out of 5 average rating, 48 reviewsIsland Dreamz Bay House -Modern 5 Star, Pool/Dock
Mar 19 – 26
Pet-friendly mansion rentals
Home in Marco Island
4.97 out of 5 average rating, 137 reviewsTigertail Beach House
Jun 8 – 15
Home in Hialeah
4.94 out of 5 average rating, 213 reviewsVIP Home located in the heart of sunny Miami
Apr 16 – 23
Home in Cutler Bay
4.99 out of 5 average rating, 149 reviewsLuxe 5BR Pool Jacuzzi Basketball
Feb 23 – Mar 2
Home in Miami
4.86 out of 5 average rating, 110 reviewsNew house with heated pool, basketball court.
Oct 4 – 11
Home in Miami
4.94 out of 5 average rating, 142 reviewsEnjoy our Beautiful Home on a Fun Canal! Hot tub!
Sep 28 – Oct 5
Home in Marathon
4.82 out of 5 average rating, 66 reviewsWelcome to Luna Island in the Florida Keys
Oct 17 – 24
Home in Key Colony Beach
4.87 out of 5 average rating, 39 reviews*Newly Renovated Single Family Home w/Private Pool
Sep 18 – 25
Home in Marathon
4.97 out of 5 average rating, 79 reviewsCoco Plum Waterfront Hideaway Home in Marathon
Sep 21 – 28
Mansion rentals with a pool
Home in Marco Island
4.96 out of 5 average rating, 136 reviewsNew Luxe Home Island Getaway, Pool & 2018 Minivan
Aug 19 – 26
Home in Marco Island
4.92 out of 5 average rating, 134 reviewsCasa De Mar- Escape to Paradise!
Aug 10 – 17
Home in Marco Island
4.94 out of 5 average rating, 52 reviewsQuick Walk to beach- Waterfront- Heated Pool-4 Bdr
Oct 25 – Nov 1
Home in Key Largo
4.97 out of 5 average rating, 60 reviewsLuxury Heated Pool/Jacuzzi, Games & Nice Backyard.
Nov 30 – Dec 7
Home in Marathon
5.0 out of 5 average rating, 9 reviewsBeautiful Home w/ Pool, Kayaks, & Golfcart
Oct 7 – 14
Home in Cudjoe Key
5.0 out of 5 average rating, 3 reviewsLatitudes-Ocean Front Pool
Nov 9 – 16
Home in Marathon
4.95 out of 5 average rating, 22 reviewsVaca Cove (C) Reel Paradise, Ocean View with Dock
Oct 10 – 17
Villa in Key Colony Beach
5.0 out of 5 average rating, 9 reviewsFabulous Canal Front Villa, Private Pool in KCB!
Jan 18 – 25
Destinations to explore
- Miami Vacation rentals
- Miami Beach Vacation rentals
- Fort Lauderdale Vacation rentals
- Boca Raton Vacation rentals
- Key West Vacation rentals
- Naples Vacation rentals
- West Palm Beach Vacation rentals
- Varadero Vacation rentals
- Havana Vacation rentals
- Nassau Vacation rentals
- Sarasota Vacation rentals
- Anna Maria Island Vacation rentals
- Mansion rentals Miami
- Mansion rentals Florida
- Mansion rentals Fort Lauderdale
- Campsite rentals Florida Keys
- Rentals with an accessible height toilet Florida Keys
- Resort rentals Florida Keys
- Pet-friendly rentals Florida Keys
- Beach condo rentals Florida Keys
- Rentals with a washer and dryer Florida Keys
- Beachfront rentals Florida Keys
- Rentals with a kayak Florida Keys
- Rentals with a fireplace Florida Keys
- Waterfront rentals Florida Keys
- Boutique hotel rentals Florida Keys
- House rentals Florida Keys
- Rentals with a fire pit Florida Keys
- Rentals with beach access Florida Keys
- Bungalow rentals Florida Keys
- Condo rentals Florida Keys
- Guesthouse rentals Florida Keys
- Fitness-friendly rentals Florida Keys
- Rentals with lake access Florida Keys
- Bed and breakfasts Florida Keys
- Monthly Rentals Florida Keys
- Boat rentals Florida Keys
- Rentals with outdoor seating Florida Keys
- Rentals with a hot tub Florida Keys
- RV rentals Florida Keys
- Rentals with a sauna Florida Keys
- Villa rentals Florida Keys
- Rentals with breakfast Florida Keys
- Rentals with a home theater Florida Keys
- Townhouse rentals Florida Keys
- Beach house rentals Florida Keys
- Apartment rentals Florida Keys
- Houseboat rentals Florida Keys
- Smoking-friendly rentals Florida Keys
- Rentals with pools Florida Keys
- Hotel rentals Florida Keys
- Rentals with an accessible height bed Florida Keys
- Kid-friendly rentals Florida Keys
- Rentals with a patio Florida Keys
- Serviced apartment rentals Florida Keys
- Private suite rentals Florida Keys
- Rentals with an EV charger Florida Keys
- Tiny house rentals Florida Keys
- Cottage rentals Florida Keys
- Family-friendly rentals Florida Keys
- Wheelchair accessible rentals Florida Keys
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes