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Seneca vacation rentals

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Top-rated vacation rentals in Seneca

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

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Shipping container in Walhalla

4.98 out of 5 average rating, 413 reviews

The Southern Cross at Hi Saw Gap

The quintessential Tiny Home experience at beautiful Hi Saw Gap! The Southern Cross is located cliff's edge with endless views over untouched natural beauty. Fabulous outdoor amenities compel you to be outside, including a glass enclosed shelter, propane fire pit, charcoal BBQ grill, and covered bistro deck with outdoor kitchen and prep station. Located just a half-mile from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and the World class Stumphouse Mountain Bike Park.

Guesthouse in Anderson

5.0 out of 5 average rating, 220 reviews

Game Day Cottage in the Woods

Great location just off of I-85 at Exit 14; less than 8 miles to Clemson University, 7 miles to Green Pond Landing, and 1000 feet to Eighteen Mile Creek Boat Landing. Our cottage is located behind our home with a beautiful wooded setting. You will find a tranquil and secluded space, yet be close enough to our areas best restaurants and entertainment. We are also close enough to the Blue Ridge Mountain for a nice day trip. Please note our rate is $240 per night during Clemson home games.

Cottage in Central

4.99 out of 5 average rating, 108 reviews

The Wildflower

Enjoy a relaxing experience at this centrally-located spot, away from the hustle and bustle but only 6 min from Clemson (10 min from Clemson University), nestled in the country in a peaceful, safe neighborhood with lots of privacy surrounding. The cottage has a front porch with 2 chairs, a 2 person hammock, grill, and a fire pit (wood is provided) with three lawn chairs. There’s a queen bed and also a CordaRoy beanbag (*bed #2) that opens up to a soft bed that sleeps 1 adult or two children.

Tiny home in West Union

4.96 out of 5 average rating, 221 reviews

Holliday's Inn Tiny Tree-house

Tiny Treehouse is a ‘container’ house set in a private wooded locale at the foothills of the mountains. Find yourself hiking at Oconee State park or Caesar's Head mountain along with a multitude of waterfalls within our county. 5 minutes from downtown historic Walhalla, 10 minutes to city of Seneca, and 20 minutes from Clemson University where tailgaters unite before the big football game! Explore the artistic venues and cultural scenes of Greenville just an hour away!

Cabin in Seneca

4.84 out of 5 average rating, 123 reviews

Getaway Lake Hartwell - Greenville

An easy drive from the city, Getaway is a new way to experience the great outdoors. Nestled across dozens of acres of private woodlands, our modern, tiny cabins have everything you need (comfy bed, bathroom, fresh linens) and nothing you don’t. Featuring a private outdoor area (hello, fire pit), each cabin is designed to help you relax, unwind and disconnect from the everyday. Plus, as part of your stay, you'll receive firewood, a s'mores kit, coffee and bottled water*.

Guesthouse in Salem

4.88 out of 5 average rating, 292 reviews

Mountain Edge Loft

Private loft apartment on 25 wooded acres, sits separate from main farm house. Private deck overlooking the woods. Everything you need for a cozy stay. Located on the edge of the Blue Ridge Escarpment with lakes Jocassee and Keowee just a few miles away. Numerous state parks, hiking, biking , waterfalls and kayaking or just peace and quiet. We are a sustainable homestead with an organic garden, chickens ,quail, dogs and cats. Our water comes from a natural spring.

Cottage in Westminster

4.98 out of 5 average rating, 431 reviews

Tiny house

BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.

Tiny home in Seneca

4.96 out of 5 average rating, 113 reviews

Windmill Cottage

You’ll treasure your time at this adorable, little cottage. It is a brand new 295 sq ft tiny house we built at the edge of the woods on our property. It has a full kitchen, bedroom with a queen bed, bathroom and living room. It is perfect for one or two people, for either a quiet get-away in the country or for someone who is in town for work and is looking for a more extended stay. We offer discounts for weekly/monthly stays!

Cottage in Townville

4.96 out of 5 average rating, 208 reviews

The Little Cottage on Pine/20 minutes to Clemson

The Cottage was created for the purpose of having a beautiful place to host our out-of-town family and friends. We chose to make it available for guests like you as well. It is tucked away in the quiet countryside of Upstate SC. Enjoy the peaceful farmland, your morning cup of coffee on the front porch, the nearby lakes and a short drive to downtown Clemson. Perfect for a relaxing weekend getaway.

Guesthouse in Westminster

4.99 out of 5 average rating, 151 reviews

Lit'l Bit O' Heaven- Rocky Top Lodge

Rocky Top Lodge is nestled in the Foothills of the Blue Ridge Mountains and was carefully designed and thoughtfully decorated. All of the décor was hand chosen over a 2 year period. Be sure to check out our sister cabin, The Farmhouse, also listed on Airbnb. Cabins are situated next to each other yet very private.

Cottage in Westminster

4.96 out of 5 average rating, 297 reviews

Chauga River Cottage

Freshly updated cottage sitting high above the Chauga River provides an intimate retreat. Come relax in the quiet setting in the woods with porches, open deck, and a river overlook. Numerous waterfalls and hiking trails nearby as well as quaint towns with coffee shops and restaurants. But staying in is highly rated.

Vacation rentals for every style

Get the amount of space that is right for you

Houses

A space thats all yours, with room for everyone

Hotels

Stylish accommodations and amenities

Unique stays

Spaces that are more than just a place to sleep

Popular amenities for Seneca vacation rentals

Laptop-friendly workspace

Air conditioning

Stay near Seneca's top sights

South Cove County Park26 locals recommend

The Escape Quest8 locals recommend

Seneca Escape Zones9 locals recommend

The Tiki Hut Lakeside Grill22 locals recommend

Oconee Lanes Inc5 locals recommend

Ingles Market17 locals recommend

Other great vacation rentals in Seneca

Home in Seneca

4.99 out of 5 average rating, 178 reviews

The Cozy Cottage

Home in Salem

4.86 out of 5 average rating, 113 reviews

Mountains and Lake Area

Condo in Clemson

4.93 out of 5 average rating, 126 reviews

Clemson Cedarwood Condo with a Deck

Home in Seneca

4.95 out of 5 average rating, 144 reviews

Private lake setting close to Clemson University

Guest suite in Seneca

4.99 out of 5 average rating, 113 reviews

Haven on the Lake-Entire downstairs, near Clemson

Guesthouse in Six Mile

4.98 out of 5 average rating, 127 reviews

Your Charming Country Cottage

Home in Pendleton

4.9 out of 5 average rating, 135 reviews

Comfort & Convenience Close to Campus

Cabin in Westminster

5.0 out of 5 average rating, 284 reviews

Lakefront Cabin Lake Hartwell *Hot Tub Dock Kayaks

Other great vacation rentals in Seneca

Home in Pendleton

4.99 out of 5 average rating, 134 reviews

3 BR/2BA Cottage in Pendleton - 9 Miles to Clemson

Cottage in Seneca

5.0 out of 5 average rating, 36 reviews

The Cottage

Tiny home in Seneca

5.0 out of 5 average rating, 32 reviews

Oak Hill Getaway

Cottage in Seneca

4.97 out of 5 average rating, 35 reviews

South Cove Cottage ~ Lake Keowee

Guest suite in Seneca

4.93 out of 5 average rating, 54 reviews

Clemson Davis Creek

Home in Westminster

4.92 out of 5 average rating, 93 reviews

Shady Rest

Home in Fair Play

5.0 out of 5 average rating, 6 reviews

Waterfall Cove - Prime

Cabin in Townville

5.0 out of 5 average rating, 26 reviews

The Frog Hollow

Quick stats about vacation rentals in Seneca

Total rentals
50 properties
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
1.7K reviews
Nightly prices starting at
$40 before taxes and fees

Frequently Asked Questions

Are there vacation rentals with a dedicated workspace in Seneca?
Yes! Work meets play with ease at over 20 vacation rentals in Seneca featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there pet-friendly vacation rentals in Seneca?
Four-legged friends are welcome in Seneca. Choose from more than 10 vacation rentals for guests traveling with pets.
How much does it cost to stay in house rentals in Seneca?
Experience the best of Seneca with our house rentals, starting at about $40 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do house rentals in Seneca have a bbq area?
Absolutely! We offer over 10 house rentals with a bbq area in Seneca. Enjoy a tailored experience with all the comforts you desire.
Are there family-friendly house rentals in Seneca?
Seneca has more than 30 family-friendly house rentals. Amenities on the property may include high chairs, travel cribs, or strollers.
Do house rentals in Seneca have wireless internet?
Absolutely! We offer over 30 house rentals with wireless internet in Seneca. Enjoy a tailored experience with all the comforts you desire.

Destinations to explore