Guesthouse vacation rentals in San Diego
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in San Diego
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for San Diego guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Chula Vista
4.95 out of 5 average rating, 477 reviewsPrivate Casita in Great Eastlake Neighborhood
Guesthouse in San Diego
4.93 out of 5 average rating, 450 reviewsPrivate Cottage in Walkable North Park w/AC
Guesthouse in San Diego
4.97 out of 5 average rating, 295 reviewsPrivate Guest House with a View
Guesthouse in San Diego
4.95 out of 5 average rating, 479 reviewsRomantic Private Garden Studio Near Downtown
Guesthouse in San Diego
4.84 out of 5 average rating, 318 reviewsPacific Beach Guest House With Garage and A/C
Guesthouse in Oceanside
4.92 out of 5 average rating, 266 reviewsThe Sunshine House. Location, Location, Ocean.
Guesthouse in La Mesa
4.92 out of 5 average rating, 208 reviewsFig Tree Bungalow
Guesthouse in El Cajon
4.98 out of 5 average rating, 191 reviewsFletcher Hills - modern 1 BR.Easy, no step access.
Guest house rentals with a patio
Guesthouse in San Diego
5.0 out of 5 average rating, 111 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
Guesthouse in San Diego
4.92 out of 5 average rating, 155 reviewsCentral studio w/ private outdoor space & parking
Guesthouse in San Diego
4.98 out of 5 average rating, 102 reviewsStunning Patio! King Bed, Walkable, Games, Parking
Guesthouse in Lakeside
4.94 out of 5 average rating, 103 reviewsSky Mesa-Adorable Cottage on the Hill
Guesthouse in La Mesa
4.98 out of 5 average rating, 252 reviewsLa Mesa Suite
Guesthouse in San Diego
4.99 out of 5 average rating, 152 reviewsAdorable cottage in Talmadge
Guesthouse in San Diego
4.98 out of 5 average rating, 128 reviewsPrivate Studio Cottage with Outdoor Patio
Guesthouse in National City
4.9 out of 5 average rating, 100 reviewsPrivate Studio ONLY 4 Miles to SD Gaslamp Quarter!
Guest house rentals with a washer and dryer
Guesthouse in San Diego
4.95 out of 5 average rating, 296 reviews*BEAUTIFUL* Sunny Home in Golden Hill
Guesthouse in San Diego
4.95 out of 5 average rating, 111 reviewsRelax in a Centrally Located, Modern Guest House
Guesthouse in San Diego
4.87 out of 5 average rating, 420 reviewsThe Golden Hill mosaic "casita"
Guesthouse in San Diego
4.94 out of 5 average rating, 106 reviewsAdorable studio/self check-in & off street parking
Guesthouse in San Diego
4.98 out of 5 average rating, 118 reviewsCasita Hermosa - Close to everything in San Diego
Guesthouse in San Diego
4.95 out of 5 average rating, 120 reviews1BR Casita in the Heart of Kensington!
Guesthouse in San Diego
4.92 out of 5 average rating, 529 reviewsThe Best Cottage in North Park!
Guesthouse in San Diego
4.99 out of 5 average rating, 133 reviewsCarrie’s North Park Casita, in Heart of San Diego
Quick stats about guesthouse rentals in San Diego
Total rentals
980 properties
Rentals with dedicated workspaces
530 properties have a dedicated workspace
Rentals with a pool
90 properties have a pool
Pet-friendly rentals
240 properties allow pets
Family-friendly rentals
140 properties are a good fit for families
Total number of reviews
101K reviews
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