Hotel vacation rentals in Upstate South Carolina

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Top-rated hotel rentals in Upstate South Carolina

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Hostel in Sunset

4.93 out of 5 average rating, 14 reviews

"White Skunk: Room at Lakeside Hostel

Your Hostel Room in Lakeside Lodge is located at Heart Ridge Retreat Center. It borders the Jocassee Gorges Wilderness and is central to lakes: Jocassee and Keowee; State Parks: Table Rock, Devil's Fork, Keowee; Waterfalls: Twin, The Narrows, Beech Bottom; hikes: Palmetto Trail Eastatoe Branch, Nine Times Preserve; cycling, mountain biking, and fishing! Your room not only has comfortable bedding, but includes access to all shared spaces in the lodge like the kitchen, family room, and patios.

Superhost

Hotel room in Sylva

4.79 out of 5 average rating, 164 reviews

204 (SMALL R00M) Click on photos for larger room.

The Tahimek Mountain Lodge is located in a secluded, pristine, mountain cove. Surrounded by tall hardwood trees, with views of the sunset and surrounding mountains. A peaceful retreat for guests seeking a quiet place to relax and enjoy nature. This room is cozy, yet small. If you prefer a larger room please click on photos to see other rooms. WiFi Tahimek Password Asheville1954 Check-in instructions provided when booked. If you require assistance please ring doorbell at Office Door.

Superhost

Nature lodge in Greenville County

4.88 out of 5 average rating, 8 reviews

Cabin near Pretty Place!

Are you tired of the business of every day life? Do you feel the need to get away and just relax? Well, you found the right place! With a queen size bedroom, this Cabin near Pretty Place is just the place for you. 10 minutes away from anything you would need for the weekend. It is only 20 minutes away Table Rock State Park and from the town of Travelers Rest with fun restaurants and the Swamp Rabbit trail. It is also 50 minutes from the beautiful city of Greenville and Pretty Place Chapel.

Superhost

Hotel room in Saluda

4.81 out of 5 average rating, 26 reviews

Beautiful Pine Room w/ View

Hey there, and welcome to our cozy little motel perched in the mountains of Saluda, NC! You'll be absolutely swept away by the breathtaking views. Our place has a snug, rustic cabin feel and we're just 5 minutes from charming Saluda, filled with quirky shops and restaurants. For adventurers, you'll be thrilled with the hiking trails, mountain biking, and zip-lining... and if you just want to kick back and relax, our courtyard is the perfect spot to hang out. Can't wait for you to join us!

Guest favorite

Shared room in Greenville

4.91 out of 5 average rating, 75 reviews

TwinXL Bed in 4-Person Female Shared Rm in Hostel

PLEASE TYPE IN "MODAL HOSTEL" IN ANY SEARCH ENGINE TO LEARN MORE ABOUT OUR PROPERTY PRIOR TO BOOKING You're booking a single Twin XL bed in a 4-person FEMALE shared room in a 20-bed, bespoke hostel, coffee shop, and art gallery in historic downtown Greenville, South Carolina. Modal serves as a hub for traveling artisans with a mixture of shared bunk-style rooms and private hotel accommodations. Our sweet spot is communal living and artistic osmosis for creative professionals & travelers.

Guest favorite

Nature lodge in Whittier

4.92 out of 5 average rating, 76 reviews

Buffalo Room at The Lodge at Smoky Cove

Nestled in the Western North Carolina Mountains. A hidden gem conveniently located just off Hwy 74 up a paved road. Enjoy the serenity of the Smokies and take in the view from a rocking chair from our front porch. Perfectly situated overlooking GSMNP, a short drive to Blue Ridge Parkway. Amazing waterfall hikes nearby for a novice or advanced hiker. Abundant trout in nearby rivers. The sweet little towns of Sylva, Dillsboro and Bryson City, Cherokee Casino just 10 minutes away.

Guest favorite

Boutique hotel in Glenville

4.91 out of 5 average rating, 67 reviews

Charles Dickens Suite By The Lake

Two Night Minimum. Welcome to Innisfree Boutique Inn By-The-Lake. Queen bed has nightstand on each side and cozy chair beside two-sided fireplace. On other side of bed there's a round table with two chairs. Wi-Fi and 55 inch high definition TV near foot of bed. Wet bar has small refrig. with creamers for Keurig Coffee Machine (bring K cups). Bathing Chamber is exquisite with large Garden Tub with view and separate shower. Veranda looks over gardens and mountains and stars.

Guest favorite

Boutique hotel in Cashiers

4.84 out of 5 average rating, 62 reviews

Boutique Hotel - Premium King Room. Best Location!

Hotel Cashiers is an upscale and conveniently located inn just a brief walk from the center of Cashiers, and a short drive from Lake Glenville, Highlands and Sapphire and nearby attractions in the Blue Ridge and Smoky Mountains. Our newly renovated Luxury King Room is a perfect blend of modern and rustic design. Our Luxury King Rooms feature light oak floors, custom furniture, heavenly bedding and luxurious toiletries. Located in the heart of Cashiers, North Carolina.

Guest favorite

Nature lodge in Sylva

5.0 out of 5 average rating, 37 reviews

Cabin Suite at the Dillsboro Inn

This cozy, one-room efficiency has a large stone fireplace and private deck. Our Riverfront Inn is on a whitewater river with sights and sounds of flowing immediately in front of each suite. We have nightly campfires and are within walking distance to our town's fine dining options and craft shops. Our region has some of the finest eco-tourism opportunities in the eastern US and our neighborhood is ' Where the Blue Ridge Mountains meets the Smokies '.

Guest favorite

Boutique hotel in Cashiers

4.88 out of 5 average rating, 247 reviews

King Room at our Boutique Bed & Brewery

Our King Room, located in the heart of Cashiers, North Carolina, is the perfect base camp for your mountain adventure! Whether you prefer to explore the beauty of the surrounding area or would rather explore a few locally crafted brews from our on-site brewery, Whiteside Brewing Co., we guarantee this room will cure what “ales” you. ;) Come dwell with us!

Hotel room in South Carolina

4.74 out of 5 average rating, 173 reviews

Furnished King Apt Nightly Brand New Facility

500+ Sq. Feet Suites With a Dedicated Living Room, Full Kitchen and Separate Bedroom From enjoying your morning coffee and breakfast in the kitchen to walking down the hall and getting ready for the day in the bedroom and separate bathroom, we’ve created an environment where guests can go about their day as if they were at home and not a hotel.

Superhost

Resort in Etowah

4.75 out of 5 average rating, 53 reviews

Standard Room at Etowah Valley Golf and Resort

Etowah Valley Golf and Resort offers pristine golf course views, low prices, accommodations, and legendary service. We strive to offer guests a great and memorable experience, as well as close proximity to Asheville, Brevard, Hendersonville, and DuPont State Forest. Catering and facility rentals available upon request.