Villa vacation rentals in Panama City
Find and book unique villas on Airbnb
Top-rated villa rentals in Panama City
Guests agree: these villas are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama City villa rentals
Private villa rentals
Villa in Panamá
Villa Monos and Momotos in Cerro Azul
Villa in Panamá
5 out of 5 average rating, 34 reviewsBreathtaking Views Mansion w/King Beds
Villa in Punta Pacifica
4.98 out of 5 average rating, 50 reviewsBeautiful House in Panama w/ King Beds + Pool
Villa in Panamá
4.89 out of 5 average rating, 27 reviewsVilla La Vista-Panama's majestic mountain hideaway
Villa in Panamá
New place to staySummit View Guest House + apartment family of 14
Villa in Veracruz
4.29 out of 5 average rating, 7 reviewsLuxurious Beach House
Villa in Panamá
4.75 out of 5 average rating, 16 reviewsSpacious Mountain Getaway in Paradise Rainforest
Villa in Panamá
5 out of 5 average rating, 3 reviewsVilla Helena Los Altos Cerro Azul-2 bedrms & pool
Villa rentals with a pool
Villa in Panamá
5 out of 5 average rating, 4 reviewsVilla Helena Los Altos Cerro Azul-1 bdrm and pool
Villa in Panamá
5 out of 5 average rating, 34 reviewsBreathtaking Views Mansion w/King Beds
Villa in Punta Pacifica
4.98 out of 5 average rating, 50 reviewsBeautiful House in Panama w/ King Beds + Pool
Villa in Panamá
4.89 out of 5 average rating, 27 reviewsVilla La Vista-Panama's majestic mountain hideaway
Villa in Panamá
New place to staySummit View Guest House + apartment family of 14
Villa in Veracruz
4.29 out of 5 average rating, 7 reviewsLuxurious Beach House
Villa in Panamá
4.5 out of 5 average rating, 6 reviewsIn the Last Lugar del Mundo (6 guests)
Villa in Panamá
4.75 out of 5 average rating, 16 reviewsSpacious Mountain Getaway in Paradise Rainforest
Villa rentals with a hot tub
Villa in Panamá
4.89 out of 5 average rating, 27 reviewsVilla La Vista-Panama's majestic mountain hideaway
Villa in Panamá
New place to staySummit View Guest House + apartment family of 14
Villa in Veracruz
4.29 out of 5 average rating, 7 reviewsLuxurious Beach House
Villa in Panamá
4.75 out of 5 average rating, 16 reviewsSpacious Mountain Getaway in Paradise Rainforest
Quick stats about villa rentals in Panama City
Total rentals
10 properties
Rentals with a pool
10 properties have a pool
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
10 properties are a good fit for families
Total number of reviews
320 reviews
Nightly prices starting at
$40 before taxes and fees
Destinations to explore
- Punta Chame Vacation rentals
- Maria Chiquita Vacation rentals
- Playa Blanca Vacation rentals
- Nueva Gorgona Vacation rentals
- Colón Vacation rentals
- Playa Santa Clara Vacation rentals
- Contadora Island Vacation rentals
- La Guaira Vacation rentals
- Anton Valley Vacation rentals
- Chicá Vacation rentals
- San Andrés Vacation rentals
- Cartagena Vacation rentals
- Beach condo rentals Panama City
- Kid-friendly rentals Panama City
- Apartment rentals Panama City
- Beachfront rentals Panama City
- Rentals with outdoor seating Panama City
- Fitness-friendly rentals Panama City
- Rentals with a patio Panama City
- Rentals with an EV charger Panama City
- Rentals with a fire pit Panama City
- Guesthouse rentals Panama City
- Beach house rentals Panama City
- Rentals with an accessible height bed Panama City
- Wheelchair accessible rentals Panama City
- Hotel rentals Panama City
- Rentals with a washer and dryer Panama City
- Rentals with a home theater Panama City
- Rentals with a sauna Panama City
- Rentals with pools Panama City
- Bed and breakfasts Panama City
- Ski-in/ski-out rentals Panama City
- Hostel rentals Panama City
- Monthly Rentals Panama City
- Smoking-friendly rentals Panama City
- Rentals with beach access Panama City
- Waterfront rentals Panama City
- Rentals with breakfast Panama City
- Pet-friendly rentals Panama City
- Serviced apartment rentals Panama City
- Condo rentals Panama City
- Family-friendly rentals Panama City
- Rentals with a fireplace Panama City
- Rentals with a hot tub Panama City
- House rentals Panama City
- Rentals with lake access Panama City
- Villa rentals Panama
- Villa rentals Panama
- Villa rentals Playa Coronado
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes