Guesthouse vacation rentals in Charleston County
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Top-rated guesthouse rentals in Charleston County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Charleston County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in North Charleston
4.94 out of 5 average rating, 351 reviewsCozy Park Circle, Charleston Guest House
Guesthouse in Charleston
4.92 out of 5 average rating, 311 reviewsMother in Law in James Island Riverland Terrace
Guesthouse in Summerville
4.98 out of 5 average rating, 651 reviews★Delightful guest house near historic plantations★
Guesthouse in Summerville
4.94 out of 5 average rating, 217 reviewsNina's Cottage -Historic Downtown Summerville
Guesthouse in Ridgeville
4.82 out of 5 average rating, 215 reviewsPond House Bungalow at Natural Gathering Grounds
Guesthouse in Charleston
4.93 out of 5 average rating, 714 reviewsCharleston's Coolest Neighborhood
Guesthouse in Charleston
4.91 out of 5 average rating, 656 reviewsIsland Oasis—Near Downtown
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 232 reviewsGreen Garden Studio @greengardenstudio2017
Guest house rentals with a patio
Guesthouse in Charleston
4.96 out of 5 average rating, 133 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in Johns Island
4.91 out of 5 average rating, 116 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in Charleston
4.98 out of 5 average rating, 132 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Charleston
4.83 out of 5 average rating, 100 reviewsGuest Suite by the Beach
Guesthouse in Goose Creek
4.94 out of 5 average rating, 53 reviewsThe Blue Secret
Guesthouse in Hanahan
4.99 out of 5 average rating, 86 reviewsThe Violet Villa w/ no cleaning fee
Guesthouse in Charleston
4.94 out of 5 average rating, 84 reviewsSpacious 1 bedroom cottage in Avondale
Guesthouse in Charleston
4.95 out of 5 average rating, 97 reviewsBoHo styled casita in adorable neighborhood...
Guest house rentals with a washer and dryer
Guesthouse in Charleston
4.99 out of 5 average rating, 152 reviewsLarge Guesthouse with Private Dock & Marsh Views
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 415 reviewsGuesthouse Convenient to Charleston, Shem Creek, and Beaches
Guesthouse in Charleston
4.99 out of 5 average rating, 214 reviewsGuest suite w/ patio, 12min to city, pet-friendly
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 261 reviews#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Guesthouse in Charleston
5.0 out of 5 average rating, 223 reviewsJames Island "La Casita" Nestled btw Beach & City
Guesthouse in Charleston
5.0 out of 5 average rating, 148 reviewsThe Guesthouse at Old Orchard
Guesthouse in Charleston
4.98 out of 5 average rating, 246 reviewsDetached Guest Suite
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 121 reviewsBeach, downtown, Alhambra Hall weddings so close!
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