Guesthouse vacation rentals in Charleston
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Top-rated guesthouse rentals in Charleston
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Charleston guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Park Circle
5 out of 5 average rating, 116 reviewsThe Park Circle Clerestory Studio Guest House
Guesthouse in Park Circle
4.93 out of 5 average rating, 352 reviewsCozy Park Circle, Charleston Guest House
Guesthouse in Charleston
4.99 out of 5 average rating, 264 reviewsSpacious Daniel Island Apartment
Guesthouse in Ridgeville
4.82 out of 5 average rating, 215 reviewsPond House Bungalow at Natural Gathering Grounds
Guesthouse in West Ashley
4.95 out of 5 average rating, 337 reviewsThe White House of Avondale
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 103 reviews5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!
Guesthouse in Summerville
4.94 out of 5 average rating, 217 reviewsNina's Cottage -Historic Downtown Summerville
Guesthouse in Park Circle
4.86 out of 5 average rating, 448 reviewsPark Circle Jungalow Loft
Guest house rentals with a patio
Guesthouse in West Ashley
4.96 out of 5 average rating, 134 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in Johns Island
4.91 out of 5 average rating, 117 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in West Ashley
4.98 out of 5 average rating, 132 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in James Island
4.83 out of 5 average rating, 102 reviewsGuest Suite by the Beach
Guesthouse in Hanahan
4.99 out of 5 average rating, 89 reviewsThe Violet Villa w/ no cleaning fee
Guesthouse in West Ashley
4.94 out of 5 average rating, 84 reviewsSpacious 1 bedroom cottage in Avondale
Guesthouse in James Island
5 out of 5 average rating, 18 reviewsGas Light Carriage House James Island
Guesthouse in West Ashley
4.95 out of 5 average rating, 97 reviewsBoHo styled casita in adorable neighborhood...
Guest house rentals with a washer and dryer
Guesthouse in Summerville
4.97 out of 5 average rating, 221 reviewsTiny Oak Cottage in Historic Downtown Summerville
Guesthouse in Park Circle
4.94 out of 5 average rating, 122 reviewsNewly Renovated Studio in Park Circle
Guesthouse in West Ashley
4.99 out of 5 average rating, 152 reviewsLarge Guesthouse with Private Dock & Marsh Views
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 121 reviewsBeach, downtown, Alhambra Hall weddings so close!
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 261 reviews#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Guesthouse in Charleston
4.98 out of 5 average rating, 247 reviewsDetached Guest Suite
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 445 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Guesthouse in James Island
5 out of 5 average rating, 223 reviewsJames Island "La Casita" Nestled btw Beach & City
Quick stats about guesthouse rentals in Charleston
Total rentals
230 properties
Rentals with dedicated workspaces
100 properties have a dedicated workspace
Rentals with a pool
10 properties have a pool
Pet-friendly rentals
50 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
23K reviews
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